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A major open challenge in neuroscience is the ability to measure and perturb neural activity in vivo from well-defined neural sub-populations at cellular resolution anywhere in the brain. However, limitations posed by scattering and…

Biological Physics · Physics 2017-11-10 Shay Ohayon , Antonio Miguel Caravaca-Aguirre , Rafael Piestun , James J. DiCarlo

In this research, we reveal the inborn but hitherto ignored properties of quantitative differential phase contrast (qDPC) imaging: the phase transfer function being an edge detection filter. Inspired by this, we highlighted the duality of…

Optimization and Control · Mathematics 2023-06-30 Shuhe Zhang , Hao Wu , Tao Peng , Zeyu Ke , Meng Shao , Tos T. J. M. Berendschot , Jinhua Zhou

Large field-of-view (FOV) microscopic imaging with high lateral resolution (1-2 microns for high space-bandwidth product) plays a pivotal role in biomedicine and biophotonics, especially within the label-free regime, e.g., for whole slide…

The new technique, multi-frequency imaging (MFI) is developed. In VLBI, Multi-Frequency Imaging (MFI) consists of multi-frequency synthesis (MFS) and multi-frequency analysis (MFA) of the VLBI data obtained from observations on various…

Astrophysics · Physics 2007-05-23 S. Likhachev

We introduce the white light quantitative phase imaging unit (WQPIU) as a practical realization of quantitative phase imaging (QPI) on standard microscope platforms. The WQPIU is a compact stand-alone unit which measures sample induced…

Optics · Physics 2016-05-04 YoonSeok Baek , KyeoReh Lee , Jonghee Yoon , Kyoohyun Kim , YongKeun Park

Quantitative susceptibility mapping (QSM) is a valuable MRI post-processing technique that quantifies the magnetic susceptibility of body tissue from phase data. However, the traditional QSM reconstruction pipeline involves multiple…

Image and Video Processing · Electrical Eng. & Systems 2022-06-27 Yang Gao , Zhuang Xiong , Amir Fazlollahi , Peter J Nestor , Viktor Vegh , Fatima Nasrallah , Craig Winter , G. Bruce Pike , Stuart Crozier , Feng Liu , Hongfu Sun

Magnetic Resonance Fingerprinting (MRF) is a time-efficient approach to quantitative MRI for multiparametric tissue mapping. The reconstruction of quantitative maps requires tailored algorithms for removing aliasing artefacts from the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-19 Perla Mayo , Matteo Cencini , Carolin M. Pirkl , Marion I. Menzel , Michela Tosetti , Bjoern H. Menze , Mohammad Golbabaee

Due to its specificity, fluorescence microscopy (FM) has become a quintessential imaging tool in cell biology. However, photobleaching, phototoxicity, and related artifacts continue to limit FM's utility. Recently, it has been shown that…

We present a proof-of-concept end-to-end system for computational extended depth of field (EDOF) imaging. The acquisition is performed through a phase-coded aperture implemented by placing a thin wavelength-dependent optical mask inside the…

Computer Vision and Pattern Recognition · Computer Science 2016-08-04 Tal Remez , Or Litany , Shachar Yoseff , Harel Haim , Alex Bronstein

Phase retrieval, or the process of recovering phase information in reciprocal space to reconstruct images from measured intensity alone, is the underlying basis to a variety of imaging applications including coherent diffraction imaging…

Computer Vision and Pattern Recognition · Computer Science 2018-11-15 Mathew J. Cherukara , Youssef S. G. Nashed , Ross J. Harder

Ultra-thin multimode optical fiber imaging promises next-generation medical endoscopes reaching high image resolution for deep tissues. However, current technology suffers from severe optical distortion, as the fiber's calibration is…

Optics · Physics 2023-10-04 Yijie Zheng , George S. D. Gordon

A major hurdle in Quantum Image Processing (QIMP) is efficiently transferring classical, high-dimensional image data into quantum states. Current methods face trade-offs: amplitude encoding (FRQI) is computationally expensive in gate…

Recovering both amplitude and phase information from a system is a fundamental goal of optical imaging. At the same time, it is crucial to operate at low photon doses to avoid altering the sample, particularly in biological applications.…

Quantum Physics · Physics 2026-01-15 Alberto Paniate , Giuseppe Ortolano , Sarika Soman , Marco Genovese , Ivano Ruo-Berchera

Fourier ptychographic microscopy (FPM) is a pivotal computational imaging technique that achieves phase and amplitude reconstruction with high resolution and wide field of view, using low numerical aperture objectives and LED array…

Lensless illumination single-pixel imaging with a multicore fiber (MCF) is a computational imaging technique that enables potential endoscopic observations of biological samples at cellular scale. In this work, we show that this technique…

Signal Processing · Electrical Eng. & Systems 2023-07-18 Olivier Leblanc , Matthias Hofer , Siddharth Sivankutty , Hervé Rigneault , Laurent Jacques

Phase retrieval, the problem of recovering lost phase information from measured intensity alone, is an inverse problem that is widely faced in various imaging modalities ranging from astronomy to nanoscale imaging. The current process of…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Henry Chan , Youssef S. G. Nashed , Saugat Kandel , Stephan Hruszkewycz , Subramanian Sankaranarayanan , Ross J. Harder , Mathew J. Cherukara

Quantitative susceptibility mapping (QSM) estimates the underlying tissue magnetic susceptibility from MRI gradient-echo phase signal and typically requires several processing steps. These steps involve phase unwrapping, brain volume…

Image and Video Processing · Electrical Eng. & Systems 2019-05-16 Hongjiang Wei , Steven Cao , Yuyao Zhang , Xiaojun Guan , Fuhua Yan , Kristen W. Yeom , Chunlei Liu

As a critical component of coherent X-ray diffraction imaging (CDI), phase retrieval has been extensively applied in X-ray structural science to recover the 3D morphological information inside measured particles. Despite meeting all the…

Image and Video Processing · Electrical Eng. & Systems 2021-10-29 Longlong Wu , Shinjae Yoo , Ana F. Suzana , Tadesse A. Assefa , Jiecheng Diao , Ross J. Harder , Wonsuk Cha , Ian K. Robinson

Purpose: To introduce a combined machine learning (ML) and physics-based image reconstruction framework that enables navigator-free, highly accelerated multishot echo planar imaging (msEPI), and demonstrate its application in…

Finite Rate of Innovation (FRI) sampling theory enables reconstruction of classes of continuous non-bandlimited signals that have a small number of free parameters from their low-rate discrete samples. This task is often translated into a…

Signal Processing · Electrical Eng. & Systems 2023-07-21 Vincent C. H. Leung , Jun-Jie Huang , Yonina C. Eldar , Pier Luigi Dragotti