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Related papers: Scaling a Variant Calling Genomics Pipeline with F…

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Chaining functions for longer workloads is a key use case for FaaS platforms in data applications. However, modern data pipelines differ significantly from typical serverless use cases (e.g., webhooks and microservices); this makes it…

Databases · Computer Science 2024-10-24 Jacopo Tagliabue , Tyler Caraza-Harter , Ciro Greco

Cloud computing offers on-demand, scalable computing and storage, and has become an essential resource for the analyses of big biomedical data. The usual approach to cloud computing requires users to reserve and provision virtual servers.…

Quantitative Methods · Quantitative Biology 2018-08-01 Dimitar Kumanov , Ling-Hong Hung , Wes Lloyd , Ka Yee Yeung

Enterprises and labs performing computationally expensive data science applications sooner or later face the problem of scale but unconnected infrastructure. For this up-scaling process, an IT service provider can be hired or in-house…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-10-12 Martin Uray , Eduard Hirsch , Gerold Katzinger , Michael Gadermayr

Serverless computing is a widely adopted cloud execution model composed of Function-as-a-Service (FaaS) and Backend-as-a-Service (BaaS) offerings. The increased level of abstraction makes vendor lock-in inherent to serverless computing,…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-03-29 Haidong Zhao , Zakaria Benomar , Tobias Pfandzelter , Nikolaos Georgantas

Serverless computing offers the potential to program the cloud in an autoscaling, pay-as-you go manner. In this paper we address critical gaps in first-generation serverless computing, which place its autoscaling potential at odds with…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-12-11 Joseph M. Hellerstein , Jose Faleiro , Joseph E. Gonzalez , Johann Schleier-Smith , Vikram Sreekanti , Alexey Tumanov , Chenggang Wu

Serverless functions provide high levels of parallelism, short startup times, and "pay-as-you-go" billing. These attributes make them a natural substrate for data analytics workflows. However, the impossibility of direct communication…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-07-26 Germán T. Eizaguirre , Marc Sánchez-Artigas , Pedro García-López

This paper provides a global picture about the deployment of networked processing services for genomic data sets. Many current research make an extensive use genomic data, which are massive and rapidly increasing over time. They are…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-09-27 Gianluca Reali , Mauro Femminella , Emilia Nunzi , Dario Valocchi

In an overloaded FaaS cluster, individual worker nodes strain under lengthening queues of requests. Although the cluster might be eventually horizontally-scaled, adding a new node takes dozens of seconds. As serving applications are tuned…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-11-01 Paweł Żuk , Bartłomiej Przybylski , Krzysztof Rzadca

Increasing popularity of the serverless computing approach has led to the emergence of new cloud infrastructures working in Container-as-a-Service (CaaS) model like AWS Fargate, Google Cloud Run, or Azure Container Instances. They introduce…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-23 Krzysztof Burkat , Maciej Pawlik , Bartosz Balis , Maciej Malawski , Karan Vahi , Mats Rynge , Rafael Ferreira da Silva , Ewa Deelman

Variant calling is a fundamental task in genomic research, essential for detecting genetic variations such as single nucleotide polymorphisms (SNPs) and insertions or deletions (indels). This paper presents an enhancement to DeepChem, a…

Quantitative Methods · Quantitative Biology 2025-07-29 Ankita Vaishnobi Bisoi , Shreyas V , Jose Siguenza , Bharath Ramsundar

Serverless computing with cloud functions is quickly gaining adoption, but constrains programmers with its limited support for state management. We introduce a shared file system for cloud functions. It offers familiar POSIX semantics while…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-09-22 Johann Schleier-Smith , Leonhard Holz , Nathan Pemberton , Joseph M. Hellerstein

Scalable and efficient processing of genome sequence data, i.e. for variant discovery, is key to the mainstream adoption of High Throughput technology for disease prevention and for clinical use. Achieving scalability, however, requires a…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-06-05 Nicholas Tucci , Jacek Cala , Jannetta Steyn , Paolo Missier

The application of serverless computing for alignment of RNA-sequences can improve many existing bioinformatics workflows by reducing operational costs and execution times. This work analyzes the applicability of serverless services for…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-08 Piotr Kica , Michał Orzechowski , Maciej Malawski

Genetic Algorithms (GAs) are a powerful technique to address hard optimisation problems. However, scalability issues might prevent them from being applied to real-world problems. Exploiting parallel GAs in the cloud might be an affordable…

Neural and Evolutionary Computing · Computer Science 2016-06-23 Pasquale Salza , Filomena Ferrucci

Serverless computing has become an important model in cloud computing and influenced the design of many applications. Here, we provide our perspective on how the recent landscape of serverless computing for scientific applications looks…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-09-06 Maciej Malawski , Bartosz Balis

Serverless computing has made it easier than ever to deploy applications over scalable cloud resources, all the while driving higher utilization for cloud providers. While this technique has worked well for easily divisible resources like…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-12-19 Nathan Pemberton , Anton Zabreyko , Zhoujie Ding , Randy Katz , Joseph Gonzalez

FaaS (Function as a Service) allows developers to upload and execute code in the cloud without managing servers. FaaS offerings from leading public cloud providers are based on system microVM or application container technologies such as…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-19 Ju Long , Hung-Ying Tai , Shen-Ta Hsieh , Michael Juntao Yuan

Advances in genome sequencing technologies generate massive amounts of sequence data that are increasingly analyzed and shared through public repositories. On-demand infrastructure services on cloud computing platforms enable the processing…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-20 Junseok Park , Eduardo A. Maury , Changhoon Oh , Donghoon Shin , Danielle Denisko , Eunjung Alice Lee

Data processing systems are increasingly deployed in the cloud. While monolithic systems run fully on virtual servers, recent systems embrace cloud infrastructure and utilize the disaggregation of compute and storage to scale them…

Databases · Computer Science 2025-01-15 Thomas Bodner , Theo Radig , David Justen , Daniel Ritter , Tilmann Rabl

Serverless computing significantly alters software development by abstracting infrastructure management and enabling rapid, modular, event-driven deployments. Despite its benefits, the distinct characteristics of serverless functions, such…

Software Engineering · Computer Science 2025-09-05 Amine Barrak , Emna Ksontini , Ridouane Atike , Fehmi Jaafar
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