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The recent success of large language models (LLMs) has paved the way for their adoption in the high-stakes domain of healthcare. Specifically, the application of LLMs in patient-trial matching, which involves assessing patient eligibility…

Artificial Intelligence · Computer Science 2023-12-18 Mauro Nievas , Aditya Basu , Yanshan Wang , Hrituraj Singh

Since the release of ChatGPT and GPT-4, large language models (LLMs) and multimodal large language models (MLLMs) have attracted widespread attention for their exceptional capabilities in understanding, reasoning, and generation,…

Computation and Language · Computer Science 2024-12-31 Hanguang Xiao , Feizhong Zhou , Xingyue Liu , Tianqi Liu , Zhipeng Li , Xin Liu , Xiaoxuan Huang

Large language models (LLMs) have rapidly advanced in clinical decision-making, yet the deployment of proprietary systems is hindered by privacy concerns and reliance on cloud-based infrastructure. Open-source alternatives allow local…

Computation and Language · Computer Science 2026-04-29 Alif Munim , Jun Ma , Omar Ibrahim , Alhusain Abdalla , Shuolin Yin , Leo Chen , Bo Wang

Incorporating large language models (LLMs) in medical question answering demands more than high average accuracy: a model that returns substantively different answers each time it is queried is not a reliable medical tool. Online health…

Information Retrieval · Computer Science 2026-04-14 Avi-ad Avraam Buskila

The use of large language models (LLMs) is expanding rapidly, and open-source versions are becoming available, offering users safer and more adaptable options. These models enable users to protect data privacy by eliminating the need to…

Machine Learning · Computer Science 2024-08-06 Hui Yin , Amir Aryani , Nakul Nambiar

Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

Computation and Language · Computer Science 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Computation and Language · Computer Science 2023-09-08 Supun Manathunga , Isuru Hettigoda

Large language models (LLMs) have shown impressive capabilities in natural language processing tasks, including dialogue generation. This research aims to conduct a novel comparative analysis of two prominent techniques, fine-tuning with…

Reasoning Large Language Models (LLMs) with enhanced accuracy and explainability are increasingly being adopted in the medical domain, as the life-critical nature of clinical decision-making demands reliable support. Despite these…

Computation and Language · Computer Science 2025-11-12 Sung-Min Lee , Siyoon Lee , Juyeon Kim , Kyoungmin Roh

Healthcare monitoring is crucial for early detection, timely intervention, and the ongoing management of health conditions, ultimately improving individuals' quality of life. Recent research shows that Large Language Models (LLMs) have…

Computation and Language · Computer Science 2024-10-01 Xin Wang , Ting Dang , Vassilis Kostakos , Hong Jia

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Large Language Models (LLMs) are central to the one-for-all intelligent paradigm, but they face a fundamental challenge when dealing with heterogeneous scientific data such as molecules: the inherent gap between discrete linguistic symbols…

Artificial Intelligence · Computer Science 2026-05-22 Yuxuan Chen , Changwei Lv , Yunduo Xiao , Zhongjing Du , Daquan Zhou , Yukun Yan , Zheni Zeng , Zhiyuan Liu

Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored,…

Computation and Language · Computer Science 2025-03-11 Pengcheng Qiu , Chaoyi Wu , Shuyu Liu , Weike Zhao , Zhuoxia Chen , Hongfei Gu , Chuanjin Peng , Ya Zhang , Yanfeng Wang , Weidi Xie

Large Language Models (LLMs) with reasoning capabilities have recently demonstrated strong potential in medical Question Answering (QA). Existing approaches are largely English-focused and primarily rely on distillation from general-purpose…

Computation and Language · Computer Science 2026-03-31 Pietro Ferrazzi , Aitor Soroa , Rodrigo Agerri

Medical multiple-choice question answering (MCQA) is particularly difficult. Questions may describe patient symptoms and ask for the correct diagnosis, which requires domain knowledge and complex reasoning. Standard language modeling…

Computation and Language · Computer Science 2023-03-14 Damien Sileo , Kanimozhi Uma , Marie-Francine Moens

We present Gazal-R1, a 32-billion-parameter language model that achieves state-of-the-art performance in medical reasoning while providing transparent, step-by-step explanations for clinical decision-making. Built upon Qwen3 32B, our model…

Computation and Language · Computer Science 2025-06-30 Ahmed M. Adly , Mostafa Samy , Amr Fawzy

Large Language Models (LLMs) hold promise in addressing complex medical problems. However, while most prior studies focus on improving accuracy and reasoning abilities, a significant bottleneck in developing effective healthcare agents lies…

Computation and Language · Computer Science 2025-10-06 Weikang Qiu , Tinglin Huang , Ryan Rullo , Yucheng Kuang , Ali Maatouk , S. Raquel Ramos , Rex Ying

Large Language Models (LLMs) have shown remarkable capabilities across various fields. However, their performance in technical domains such as telecommunications remains underexplored. This paper evaluates two open-source LLMs, Gemma 3 27B…

Networking and Internet Architecture · Computer Science 2025-09-29 Arina Caraus , Alessio Buscemi , Sumit Kumar , Ion Turcanu

Background: Large language models (LLMs) such as OpenAI's GPT-4 or Google's PaLM 2 are proposed as viable diagnostic support tools or even spoken of as replacements for "curbside consults". However, even LLMs specifically trained on medical…

Artificial Intelligence · Computer Science 2024-10-21 Gioele Barabucci , Victor Shia , Eugene Chu , Benjamin Harack , Nathan Fu

Artificially intelligent (AI) co-scientists must be able to sift through research literature cost-efficiently while applying nuanced scientific reasoning. We evaluate Small Language Models (SLMs, <= 8B parameters) for classifying medical…

Computational Engineering, Finance, and Science · Computer Science 2025-12-09 Muhammed Muaaz Dawood , Mohammad Zaid Moonsamy , Kaela Kokkas , Hairong Wang , Robert F. Breiman , Richard Klein , Emmanuel K. Sekyi , Bruce A. Bassett
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