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Objective. This paper presents an overview of generalizable and explainable artificial intelligence (XAI) in deep learning (DL) for medical imaging, aimed at addressing the urgent need for transparency and explainability in clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Ahmad Chaddad , Yan Hu , Yihang Wu , Binbin Wen , Reem Kateb

Deep learning is becoming increasingly adopted in business and industry due to its ability to transform large quantities of data into high-performing models. These models, however, are generally regarded as black boxes, which, in spite of…

Machine Learning · Computer Science 2023-02-21 Stefan Druc , Peter Wooldridge , Adarsh Krishnamurthy , Soumik Sarkar , Aditya Balu

Explainable AI (XAI) is an active research area to interpret a neural network's decision by ensuring transparency and trust in the task-specified learned models. Recently, perturbation-based model analysis has shown better interpretation,…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Mahesh Sudhakar , Sam Sattarzadeh , Konstantinos N. Plataniotis , Jongseong Jang , Yeonjeong Jeong , Hyunwoo Kim

Explainable Artificial Intelligence (XAI) provides tools to help understanding how the machine learning models work and reach a specific outcome. It helps to increase the interpretability of models and makes the models more trustworthy and…

In this paper we propose a new framework for evaluating the performance of explanation methods on the decisions of a deepfake detector. This framework assesses the ability of an explanation method to spot the regions of a fake image with…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Konstantinos Tsigos , Evlampios Apostolidis , Spyridon Baxevanakis , Symeon Papadopoulos , Vasileios Mezaris

Computer Vision, and hence Artificial Intelligence-based extraction of information from images, has increasingly received attention over the last years, for instance in medical diagnostics. While the algorithms' complexity is a reason for…

Human-Computer Interaction · Computer Science 2020-07-14 Christian Meske , Enrico Bunde

The use of deep learning in computer vision tasks such as image classification has led to a rapid increase in the performance of such systems. Due to this substantial increment in the utility of these systems, the use of artificial…

Image and Video Processing · Electrical Eng. & Systems 2023-04-05 Vinay Jogani , Joy Purohit , Ishaan Shivhare , Seema C Shrawne

Explainable Artificial Intelligence (XAI) plays a crucial role in fostering transparency and trust in AI systems, where traditional XAI approaches typically offer one level of abstraction for explanations, often in the form of heatmaps…

Explainable AI (XAI) and interpretable machine learning methods help to build trust in model predictions and derived insights, yet also present a perverse incentive for analysts to manipulate XAI metrics to support pre-specified…

Machine Learning · Computer Science 2025-07-16 Rahul Sharma , Sergey Redyuk , Sumantrak Mukherjee , Andrea Šipka , Eyke Hüllermeier , Sebastian Vollmer , David Selby

An explainable AI (XAI) model aims to provide transparency (in the form of justification, explanation, etc) for its predictions or actions made by it. Recently, there has been a lot of focus on building XAI models, especially to provide…

Human-Computer Interaction · Computer Science 2022-01-11 Arjun Akula , Song-Chun Zhu

Black-box nature of Artificial Intelligence (AI) models do not allow users to comprehend and sometimes trust the output created by such model. In AI applications, where not only the results but also the decision paths to the results are…

Artificial Intelligence · Computer Science 2024-10-28 Ibrahim Kok , Feyza Yildirim Okay , Ozgecan Muyanli , Suat Ozdemir

EXplainable AI (XAI) is an essential topic to improve human understanding of deep neural networks (DNNs) given their black-box internals. For computer vision tasks, mainstream pixel-based XAI methods explain DNN decisions by identifying…

Computer Vision and Pattern Recognition · Computer Science 2023-05-18 Ao Sun , Pingchuan Ma , Yuanyuan Yuan , Shuai Wang

Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

Human understandable explanation of deep learning models is essential for various critical and sensitive applications. Unlike image or tabular data where the importance of each input feature (for the classifier's decision) can be directly…

Machine Learning · Computer Science 2025-04-07 Shahbaz Rezaei , Xin Liu

With the widespread use of sophisticated machine learning models in sensitive applications, understanding their decision-making has become an essential task. Models trained on tabular data have witnessed significant progress in explanations…

Machine Learning · Computer Science 2022-06-16 Aditya Lahiri , Kamran Alipour , Ehsan Adeli , Babak Salimi

Explainable artificial intelligence (XAI) methods lack ground truth. In its place, method developers have relied on axioms to determine desirable properties for their explanations' behavior. For high stakes uses of machine learning that…

Machine Learning · Computer Science 2022-09-02 Isha Hameed , Samuel Sharpe , Daniel Barcklow , Justin Au-Yeung , Sahil Verma , Jocelyn Huang , Brian Barr , C. Bayan Bruss

Artificial intelligence has become pervasive across disciplines and fields, and biomedical image and signal processing is no exception. The growing and widespread interest on the topic has triggered a vast research activity that is…

Machine Learning · Computer Science 2022-07-12 Guang Yang , Arvind Rao , Christine Fernandez-Maloigne , Vince Calhoun , Gloria Menegaz

Explainable AI (XAI) methods provide explanations of AI models, but our understanding of how they compare with human explanations remains limited. In image classification, we found that humans adopted more explorative attention strategies…

Human-Computer Interaction · Computer Science 2023-04-11 Ruoxi Qi , Yueyuan Zheng , Yi Yang , Caleb Chen Cao , Janet H. Hsiao

Deep Learning (DL) models processing images to recognize the health state of large infrastructure components can exhibit biases and rely on non-causal shortcuts. eXplainable Artificial Intelligence (XAI) can address these issues but…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Giovanni Floreale , Piero Baraldi , Enrico Zio , Olga Fink

The critical need for transparent and trustworthy machine learning in cybersecurity operations drives the development of this integrated Explainable AI (XAI) framework. Our methodology addresses three fundamental challenges in deploying AI…

Cryptography and Security · Computer Science 2026-02-24 Norrakith Srisumrith , Sunantha Sodsee
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