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Automatic relationship extraction (RE) from biomedical literature is critical for managing the vast amount of scientific knowledge produced each year. In recent years, utilizing pre-trained language models (PLMs) has become the prevalent…

Computation and Language · Computer Science 2025-11-04 Mario Sänger , Ulf Leser

Automatic disease diagnosis has become increasingly valuable in clinical practice. The advent of large language models (LLMs) has catalyzed a paradigm shift in artificial intelligence, with growing evidence supporting the efficacy of LLMs…

Rare diseases, including Inborn Errors of Metabolism (IEM), pose significant diagnostic challenges. Case reports serve as key but computationally underutilized resources to inform diagnosis. Clinical dense information extraction refers to…

Computation and Language · Computer Science 2025-05-26 Xiao Yu Cindy Zhang , Carlos R. Ferreira , Francis Rossignol , Raymond T. Ng , Wyeth Wasserman , Jian Zhu

Large language models (LLMs) show promise for supporting clinical decision-making in complex fields such as rheumatology. Our evaluation shows that smaller language models (SLMs), combined with retrieval-augmented generation (RAG), achieve…

Computation and Language · Computer Science 2025-07-11 Sabine Felde , Rüdiger Buchkremer , Gamal Chehab , Christian Thielscher , Jörg HW Distler , Matthias Schneider , Jutta G. Richter

The rapid advancement of Large Language Models (LLMs) has significantly influenced various domains, leveraging their exceptional few-shot and zero-shot learning capabilities. In this work, we aim to explore and understand the LLMs-based…

Artificial Intelligence · Computer Science 2024-10-24 Dawei Li , Zhen Tan , Huan Liu

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

Despite the impressive capabilities of Large Language Models (LLMs) in general medical domains, questions remain about their performance in diagnosing rare diseases. To answer this question, we aim to assess the diagnostic performance of…

Computational Engineering, Finance, and Science · Computer Science 2024-08-19 Guanchu Wang , Junhao Ran , Ruixiang Tang , Chia-Yuan Chang , Chia-Yuan Chang , Yu-Neng Chuang , Zirui Liu , Vladimir Braverman , Zhandong Liu , Xia Hu

Recent advancements in Large Language Models (LLMs) have drawn increasing attention since the learned embeddings pretrained on large-scale datasets have shown powerful ability in various downstream applications. However, whether the learned…

Computation and Language · Computer Science 2023-02-07 Jielin Qiu , William Han , Jiacheng Zhu , Mengdi Xu , Michael Rosenberg , Emerson Liu , Douglas Weber , Ding Zhao

This article investigates a zero-shot approach to hypernymy prediction using large language models (LLMs). The study employs a method based on text probability calculation, applying it to various generated prompts. The experiments…

Computation and Language · Computer Science 2024-01-10 Mikhail Tikhomirov , Natalia Loukachevitch

Alzheimer's disease (AD) has become a prevalent neurodegenerative disease worldwide. Traditional diagnosis still relies heavily on medical imaging and clinical assessment by physicians, which is often time-consuming and resource-intensive…

Computation and Language · Computer Science 2026-02-17 Tongze Zhang , Jun-En Ding , Melik Ozolcer , Fang-Ming Hung , Albert Chih-Chieh Yang , Feng Liu , Yi-Rou Ji , Sang Won Bae

With large training datasets and massive amounts of computing sources, large language models (LLMs) achieve remarkable performance in comprehensive and generative ability. Based on those powerful LLMs, the model fine-tuned with…

Computation and Language · Computer Science 2024-01-12 Xuyang Zhao , Qibin Zhao , Toshihisa Tanaka

Most of the existing medication recommendation models are predicted with only structured data such as medical codes, with the remaining other large amount of unstructured or semi-structured data underutilization. To increase the utilization…

Computation and Language · Computer Science 2024-07-16 Yu-Tzu Lee

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

This study concentrates on evaluating the efficacy of Large Language Models (LLMs) in healthcare, with a specific focus on their application in personal anomalous health monitoring. Our research primarily investigates the capabilities of…

Machine Learning · Computer Science 2023-11-22 Jiankai Tang , Kegang Wang , Hongming Hu , Xiyuxing Zhang , Peiyu Wang , Xin Liu , Yuntao Wang

Large language models (LLMs) are increasingly being used in a zero-shot fashion to assess mental health conditions, yet we have limited knowledge on what factors affect their accuracy. In this study, we utilize a clinical dataset of natural…

Large language models (LLMs) have demonstrated capabilities across diverse domains, yet their performance on rare disease diagnosis from narrative medical cases remains underexplored. We introduce a novel dataset of 176 symptom-diagnosis…

Computation and Language · Computer Science 2025-11-17 Arsh Gupta , Ajay Narayanan Sridhar , Bonam Mingole , Amulya Yadav

Financial sentiment analysis is critical for valuation and investment decision-making. Traditional NLP models, however, are limited by their parameter size and the scope of their training datasets, which hampers their generalization…

Computation and Language · Computer Science 2023-11-07 Boyu Zhang , Hongyang Yang , Tianyu Zhou , Ali Babar , Xiao-Yang Liu

The ability to predict drug overdose risk from a patient's medical records is crucial for timely intervention and prevention. Traditional machine learning models have shown promise in analyzing longitudinal medical records for this task.…

Artificial Intelligence · Computer Science 2025-04-17 Md Sultan Al Nahian , Chris Delcher , Daniel Harris , Peter Akpunonu , Ramakanth Kavuluru

The robust and accurate recognition of multicultural names, particularly those not previously encountered, is a critical challenge in an increasingly globalized digital landscape. Traditional methods often falter when confronted with the…

Computation and Language · Computer Science 2025-07-08 Thanakorn Phonchai , Surasakdi Siripong , Nicholas Patterson , Owen Campbell

Large language models (LLMs) have demonstrated exceptional capabilities in planning and tool utilization as autonomous agents, but few have been developed for medical problem-solving. We propose EHRAgent, an LLM agent empowered with a code…

Computation and Language · Computer Science 2024-10-07 Wenqi Shi , Ran Xu , Yuchen Zhuang , Yue Yu , Jieyu Zhang , Hang Wu , Yuanda Zhu , Joyce Ho , Carl Yang , May D. Wang