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Many scholars have called for raising statistical hurdles to guard against false discoveries in academic publications. I show these calls may be difficult to justify empirically. Published data exhibit bias: results that fail to meet…

General Finance · Quantitative Finance 2024-04-09 Andrew Y. Chen

For some variants of regression models, including partial, measurement error or error-in-variables, latent effects, semi-parametric and otherwise corrupted linear models, the classical parametric tests generally do not perform well. Various…

Statistics Theory · Mathematics 2015-03-25 Pranab K. Sen , Jana Jureckova , Jan Picek

This chapter demystifies P-values, hypothesis tests and significance tests, and introduces the concepts of local evidence and global error rates. The local evidence is embodied in \textit{this} data and concerns the hypotheses of interest…

Other Statistics · Statistics 2019-10-07 Michael J. Lew

The widespread use of generative models has created a feedback loop, in which each generation of models is trained on data partially produced by its predecessors. This process has raised concerns about model collapse: A critical degradation…

Machine Learning · Statistics 2026-03-27 Daniel Barzilai , Ohad Shamir

Current language generation models suffer from issues such as repetition, incoherence, and hallucinations. An often-repeated hypothesis is that this brittleness of generation models is caused by the training and the generation procedure…

Computation and Language · Computer Science 2023-01-11 Kushal Arora , Layla El Asri , Hareesh Bahuleyan , Jackie Chi Kit Cheung

The influential claim that most published results are false raised concerns about the trustworthiness and integrity of science. Since then, there have been numerous attempts to examine the rate of false-positive results that have failed to…

Applications · Statistics 2023-09-19 Ulrich Schimmack , František Bartoš

Clinical research should conform to high standards of ethical and scientific integrity, given that human lives are at stake. However, economic incentives can generate conflicts of interest for investigators, who may be inclined to withhold…

General Economics · Economics 2022-10-12 Jérôme Adda , Christian Decker , Marco Ottaviani

It has long been noticed that the efficacy observed in small early phase studies is generally better than that observed in later larger studies. Historically, the inflation of the efficacy results from early proof-of-concept studies is…

Methodology · Statistics 2020-06-11 Yongming Qu , Yu Du , Ying Zhang , Lei Shen

In research on eye movements in reading, it is common to analyze a number of canonical dependent measures to study how the effects of a manipulation unfold over time. Although this gives rise to the well-known multiple comparisons problem,…

Applications · Statistics 2016-10-11 Titus von der Malsburg , Bernhard Angele

We study the assessment of semiparametric and other highly-parametrised models from the perspective of foundational principles of parametric statistical inference. In doing so, we highlight the possibility of avoiding the usual…

Methodology · Statistics 2026-05-05 Heather Battey , Nancy Reid

For many applications, it is critical to interpret and validate groups of observations obtained via clustering. A common validation approach involves testing differences in feature means between observations in two estimated clusters. In…

Methodology · Statistics 2023-11-29 Yiqun T. Chen , Lucy L. Gao

There is a well-known problem in Null Hypothesis Significance Testing: many statistically significant results fail to replicate in subsequent experiments. We show that this problem arises because standard `point-form null' significance…

Methodology · Statistics 2025-02-06 Fintan Costello , Paul Watts

While P-values are widely abused, they are a useful tool for many purposes; banning them is analogous to banning scalpels because most people do not know how to perform surgery. Many reported P-values are not genuine P-values, for a variety…

Other Statistics · Statistics 2022-04-19 Philip B. Stark

The growing need for trustworthy machine learning has led to the blossom of interpretability research. Numerous explanation methods have been developed to serve this purpose. However, these methods are deficiently and inappropriately…

Machine Learning · Computer Science 2022-03-29 Yipei Wang , Xiaoqian Wang

The use of machine learning (ML) methods for prediction and forecasting has become widespread across the quantitative sciences. However, there are many known methodological pitfalls, including data leakage, in ML-based science. In this…

Machine Learning · Computer Science 2022-07-15 Sayash Kapoor , Arvind Narayanan

Quantitative research relies heavily on coding, and coding errors are relatively common even in published research. In this paper, we examine whether individuals are more or less likely to check their code depending on the results they…

General Economics · Economics 2025-09-26 Bruno Ferman , Lucas Finamor

Researchers are more likely to share notable findings. As a result, published findings tend to overstate the magnitude of real-world phenomena. This bias is a natural concern for asset pricing research, which has found hundreds of return…

General Finance · Quantitative Finance 2023-09-22 Andrew Y. Chen , Tom Zimmermann

Recent research has generated hope that inference scaling, such as resampling solutions until they pass verifiers like unit tests, could allow weaker models to match stronger ones. Beyond inference, this approach also enables training…

Machine Learning · Computer Science 2026-03-27 Benedikt Stroebl , Sayash Kapoor , Arvind Narayanan

Studies accumulate over time and meta-analyses are mainly retrospective. These two characteristics introduce dependencies between the analysis time, at which a series of studies is up for meta-analysis, and results within the series.…

Methodology · Statistics 2019-10-21 Judith ter Schure , Peter D. Grünwald

We show that some forms of p-hacking cannot be detected by examining the histogram of t-statistics or their p-values. Even when p-hacking is detectable, standard tests may lack power. We propose a novel test that detects every form of…

Econometrics · Economics 2026-05-14 Stefan Faridani
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