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There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

Automatic text summarization (ATS) is an emerging technology to assist clinicians in providing continuous and coordinated care. This study presents an approach to summarize doctor-patient dialogues using generative large language models…

Computation and Language · Computer Science 2024-03-21 Mengxian Lyu , Cheng Peng , Xiaohan Li , Patrick Balian , Jiang Bian , Yonghui Wu

The progress in natural language processing (NLP) using large language models (LLMs) has greatly improved patient information extraction from clinical narratives. However, most methods based on the fine-tuning strategy have limited transfer…

Computation and Language · Computer Science 2024-03-20 Cheng Peng , Zehao Yu , Kaleb E Smith , Wei-Hsuan Lo-Ciganic , Jiang Bian , Yonghui Wu

Objective To develop soft prompt-based learning algorithms for large language models (LLMs), examine the shape of prompts, prompt-tuning using frozen/unfrozen LLMs, transfer learning, and few-shot learning abilities. Methods We developed a…

Computation and Language · Computer Science 2024-04-16 Cheng Peng , Xi Yang , Kaleb E Smith , Zehao Yu , Aokun Chen , Jiang Bian , Yonghui Wu

Natural language processing (NLP) is a key technology to extract important patient information from clinical narratives to support healthcare applications. The rapid development of large language models (LLMs) has revolutionized many NLP…

Computation and Language · Computer Science 2025-09-08 Cheng Peng , Xinyu Dong , Mengxian Lyu , Daniel Paredes , Yaoyun Zhang , Yonghui Wu

Large Language Models (LLMs) have revolutionized the field of Natural Language Processing thanks to their ability to reuse knowledge acquired on massive text corpora on a wide variety of downstream tasks, with minimal (if any) tuning steps.…

Computation and Language · Computer Science 2024-07-12 Flavio Petruzzellis , Alberto Testolin , Alessandro Sperduti

While large language models (LLMs), such as GPT-3, appear to be robust and general, their reasoning ability is not at a level to compete with the best models trained for specific natural language reasoning problems. In this study, we…

Computation and Language · Computer Science 2023-07-18 Zhun Yang , Adam Ishay , Joohyung Lee

Large language models (LLMs) enable system builders today to create competent NLP systems through prompting, where they only need to describe the task in natural language and provide a few examples. However, in other ways, LLMs are a step…

Computation and Language · Computer Science 2023-08-24 Vijay Viswanathan , Chenyang Zhao , Amanda Bertsch , Tongshuang Wu , Graham Neubig

There is an increasing interest in developing artificial intelligence (AI) systems to process and interpret electronic health records (EHRs). Natural language processing (NLP) powered by pretrained language models is the key technology for…

Large language models (LLMs) have gained considerable attention for Artificial Intelligence Generated Content (AIGC), particularly with the emergence of ChatGPT. However, the direct adaptation of continuous speech to LLMs that process…

Audio and Speech Processing · Electrical Eng. & Systems 2023-08-28 Haibin Wu , Kai-Wei Chang , Yuan-Kuei Wu , Hung-yi Lee

Objective: This paper aims to prompt large language models (LLMs) for clinical temporal relation extraction (CTRE) in both few-shot and fully supervised settings. Materials and Methods: This study utilizes four LLMs: Encoder-based…

Computation and Language · Computer Science 2024-12-09 Jianping He , Laila Rasmy , Haifang Li , Jianfu Li , Zenan Sun , Evan Yu , Degui Zhi , Cui Tao

This study introduces GPTA, a Large Language Model assistance training framework, that enhances the training of downstream task models via prefix prompt. By minimizing data exposure to LLM, the framework addresses the security and legal…

Computation and Language · Computer Science 2024-04-02 Xiao Liu , Jiawei Zhang

Over the past decade, extensive research efforts have been dedicated to the extraction of information from textual process descriptions. Despite the remarkable progress witnessed in natural language processing (NLP), information extraction…

Computation and Language · Computer Science 2024-07-29 Julian Neuberger , Lars Ackermann , Han van der Aa , Stefan Jablonski

AI tasks encompass a wide range of domains and fields. While numerous AI models have been designed for specific tasks and applications, they often require considerable human efforts in finding the right model architecture, optimization…

Computation and Language · Computer Science 2023-05-05 Shujian Zhang , Chengyue Gong , Lemeng Wu , Xingchao Liu , Mingyuan Zhou

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

Generative Pretrained Transformers (GPTs) are foundational Large Language Models (LLMs) for text generation. However, individual LLMs often produce inconsistent outputs and exhibit biases, limiting their representation of diverse language…

Computation and Language · Computer Science 2025-08-06 Mari Ashiga , Wei Jie , Fan Wu , Vardan Voskanyan , Fateme Dinmohammadi , Paul Brookes , Jingzhi Gong , Zheng Wang

Phenotype-driven gene prioritization is a critical process in the diagnosis of rare genetic disorders for identifying and ranking potential disease-causing genes based on observed physical traits or phenotypes. While traditional approaches…

Quantitative Methods · Quantitative Biology 2024-04-04 Junyoung Kim , Jingye Yang , Kai Wang , Chunhua Weng , Cong Liu

Research into methods for improving the performance of large language models (LLMs) through fine-tuning, retrieval-augmented generation (RAG) and soft-prompting has tended to focus on the use of highly technical or high-cost techniques,…

Entity Linking in natural language processing seeks to match text entities to their corresponding entries in a dictionary or knowledge base. Traditional approaches rely on contextual models, which can be complex, hard to train, and have…

Computation and Language · Computer Science 2025-05-23 Yifan Ding , Amrit Poudel , Qingkai Zeng , Tim Weninger , Balaji Veeramani , Sanmitra Bhattacharya

While Large Language Models (LLMs) are being quickly adapted to many domains, including healthcare, their strengths and pitfalls remain under-explored. In our study, we examine the effects of prompt engineering to guide Large Language…

Computation and Language · Computer Science 2024-09-04 Daniil Filienko , Yinzhou Wang , Caroline El Jazmi , Serena Xie , Trevor Cohen , Martine De Cock , Weichao Yuwen
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