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There has been a growing interest in covariate adjustment in the analysis of randomized controlled trials in past years. For instance, the U.S. Food and Drug Administration recently issued guidance that emphasizes the importance of…

Methodology · Statistics 2023-06-12 Kelly Van Lancker , Frank Bretz , Oliver Dukes

In this note, we propose and study the notion of modified Fej\'{e}r sequences. Within a Hilbert space setting, we show that it provides a unifying framework to prove convergence rates for objective function values of several optimization…

Optimization and Control · Mathematics 2015-10-16 Junhong Lin , Lorenzo Rosasco , Silvia Villa , Ding-Xuan Zhou

Traditionally, spline or kernel approaches in combination with parametric estimation are used to infer the linear coefficient (fixed effects) in a partially linear mixed-effects model for repeated measurements. Using machine learning…

Methodology · Statistics 2023-04-03 Corinne Emmenegger , Peter Bühlmann

We propose a novel framework to study asynchronous federated learning optimization with delays in gradient updates. Our theoretical framework extends the standard FedAvg aggregation scheme by introducing stochastic aggregation weights to…

Machine Learning · Computer Science 2022-06-22 Yann Fraboni , Richard Vidal , Laetitia Kameni , Marco Lorenzi

Inferring unbiased treatment effects has received widespread attention in the machine learning community. In recent years, our community has proposed numerous solutions in standard settings, high-dimensional treatment settings, and even…

Machine Learning · Computer Science 2024-03-19 Krzysztof Kacprzyk , Samuel Holt , Jeroen Berrevoets , Zhaozhi Qian , Mihaela van der Schaar

Forced-choice conjoint designs have become a staple method in the experimentalist's toolkit. However, the forced-choice outcome is neither always consistent with the types of choices individuals make in real political contexts, nor is it…

Methodology · Statistics 2026-04-17 Thomas S. Robinson , Mats Ahrenshop , Spyros Kosmidis

Federated learning (FL) allows remote clients to train a global model collaboratively while protecting client privacy. Despite its privacy-preserving benefits, FL has significant drawbacks, including slow convergence, high communication…

Machine Learning · Computer Science 2026-02-18 Mohammad Partohaghighi , Roummel Marcia , YangQuan Chen

This paper introduces a novel approach for estimating heterogeneous treatment effects of binary treatment in panel data, particularly focusing on short panel data with large cross-sectional data and observed confoundings. In contrast to…

Methodology · Statistics 2024-06-05 Meijia Wang , Ignacio Martinez , P. Richard Hahn

For federated learning (FL) algorithms such as FedSAM, their generalization capability is crucial for real-word applications. In this paper, we revisit the generalization problem in FL and investigate the impact of data heterogeneity on FL…

Machine Learning · Computer Science 2026-04-21 Liu junkang , Yuanyuan Liu , Fanhua Shang , Hongying Liu , Jin Liu , Wei Feng

In randomized clinical trials, adjustments for baseline covariates at both design and analysis stages are highly encouraged by regulatory agencies. A recent trend is to use a model-assisted approach for covariate adjustment to gain…

Methodology · Statistics 2021-07-14 Ting Ye , Jun Shao , Yanyao Yi , Qingyuan Zhao

In this study, we compared two groups, in which subjects were assigned to either the treatment or the control group. In such trials, if the efficacy of the treatment cannot be demonstrated in a population that meets the eligibility…

Methodology · Statistics 2024-07-26 Shintaro Yuki , Kensuke Tanioka , Hiroshi Yadohisa

We present a general framework for using existing data to estimate the efficiency gain from using a covariate-adjusted estimator of a marginal treatment effect in a future randomized trial. We describe conditions under which it is possible…

Methodology · Statistics 2021-05-03 Xiudi Li , Sijia Li , Alex Luedtke

This paper develops a design-first econometric framework for event-study and difference-in-differences estimands under staggered adoption with heterogeneous effects, emphasising (i) exact probability limits for conventional two-way fixed…

Econometrics · Economics 2026-01-28 Craig S Wright

Weighted average derivative effects (WADEs) are nonparametric estimands with uses in economics and causal inference. Debiased WADE estimators typically require learning the conditional mean outcome as well as a Riesz representer (RR) that…

Methodology · Statistics 2024-04-10 Oliver Hines , Karla Diaz-Ordaz , Stijn Vansteelandt

Model-heterogeneous personalized federated learning (MHPFL) enables FL clients to train structurally different personalized models on non-independent and identically distributed (non-IID) local data. Existing MHPFL methods focus on…

Machine Learning · Computer Science 2024-04-30 Liping Yi , Han Yu , Chao Ren , Heng Zhang , Gang Wang , Xiaoguang Liu , Xiaoxiao Li

This article focuses on parameter estimation of multi-levels nonlinear mixed effects models (MNLMEMs). These models are used to analyze data presenting multiple hierarchical levels of grouping (cluster data, clinical trials with several…

Methodology · Statistics 2008-12-18 Xavière Panhard , Adeline Samson

The average treatment effect (ATE) is commonly used to quantify the main effect of a binary treatment on an outcome. Extensions to continuous treatments are usually based on the dose-response curve or shift interventions, but both require…

Statistics Theory · Mathematics 2026-03-02 Oliver J. Hines , Karla Diaz-Ordaz , Stijn Vansteelandt

Federated edge learning (FEEL) enables collaborative model training across distributed clients over wireless networks without exposing raw data. While most existing studies assume static datasets, in real-world scenarios clients may…

Machine Learning · Computer Science 2025-09-10 Yuxuan Bai , Yuxuan Sun , Tan Chen , Wei Chen , Sheng Zhou , Zhisheng Niu

Federated learning is a privacy-preserving machine learning technique that learns a shared model across decentralized clients. It can alleviate privacy concerns of personal re-identification, an important computer vision task. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2020-10-12 Weiming Zhuang , Yonggang Wen , Xuesen Zhang , Xin Gan , Daiying Yin , Dongzhan Zhou , Shuai Zhang , Shuai Yi

This paper considers the problem of design-based inference for the average treatment effect in finely stratified experiments. Here, by "design-based'' we mean that the only source of uncertainty stems from the randomness in treatment…

Econometrics · Economics 2025-05-08 Yuehao Bai , Xun Huang , Joseph P. Romano , Azeem M. Shaikh , Max Tabord-Meehan