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Synthetic Electronic Health Records (EHRs) offer a valuable opportunity to create privacy preserving and harmonized structured data, supporting numerous applications in healthcare. Key benefits of synthetic data include precise control over…

Computation and Language · Computer Science 2025-04-28 Yihan Lin , Zhirong Bella Yu , Simon Lee

Generative models have recently achieved remarkable success and widespread adoption in society, yet they often struggle to generate realistic and accurate outputs. This challenge extends beyond language and vision into fields like…

Machine Learning · Computer Science 2024-12-03 Lyle Regenwetter , Giorgio Giannone , Akash Srivastava , Dan Gutfreund , Faez Ahmed

This paper presents a comprehensive systematic review of generative models (GANs, VAEs, DMs, and LLMs) used to synthesize various medical data types, including imaging (dermoscopic, mammographic, ultrasound, CT, MRI, and X-ray), text,…

Score-based generative models (SGMs) have demonstrated unparalleled sampling quality and diversity in numerous fields, such as image generation, voice synthesis, and tabular data synthesis, etc. Inspired by those outstanding results, we…

Machine Learning · Computer Science 2025-11-27 Haksoo Lim , Jaehoon Lee , Sewon Park , Minjung Kim , Noseong Park

Stable diffusion models represent the state-of-the-art in data synthesis across diverse domains and hold transformative potential for applications in science and engineering, e.g., by facilitating the discovery of novel solutions and…

Machine Learning · Computer Science 2025-10-23 Stefano Zampini , Jacob K. Christopher , Luca Oneto , Davide Anguita , Ferdinando Fioretto

High-quality synthetic data can support the development of effective predictive models for biomedical tasks, especially in rare diseases or when subject to compelling privacy constraints. These limitations, for instance, negatively impact…

Machine Learning · Computer Science 2023-01-24 Lorenzo Simone , Davide Bacciu

In real-world applications of natural language generation, there are often constraints on the target sentences in addition to fluency and naturalness requirements. Existing language generation techniques are usually based on recurrent…

Computation and Language · Computer Science 2019-02-05 Ning Miao , Hao Zhou , Lili Mou , Rui Yan , Lei Li

Data sparsity is a well-known problem for grammatical error correction (GEC). Generating synthetic training data is one widely proposed solution to this problem, and has allowed models to achieve state-of-the-art (SOTA) performance in…

Computation and Language · Computer Science 2022-08-23 Chowdhury Rafeed Rahman

Retrieval-augmented generation (RAG) systems trained using reinforcement learning (RL) with reasoning are hampered by inefficient context management, where long, noisy retrieved documents increase costs and degrade performance. We introduce…

Computation and Language · Computer Science 2025-10-14 Zhichao Xu , Minheng Wang , Yawei Wang , Wenqian Ye , Yuntao Du , Yunpu Ma , Yijun Tian

Many modern sequential recommender systems use deep neural networks, which can effectively estimate the relevance of items but require a lot of time to train. Slow training increases expenses, hinders product development timescales and…

Information Retrieval · Computer Science 2022-07-18 Aleksandr Petrov , Craig Macdonald

In recent years, deep learning has been successfully adopted in a wide range of applications related to electronic health records (EHRs) such as representation learning and clinical event prediction. However, due to privacy constraints,…

Machine Learning · Computer Science 2023-09-04 Chang Lu , Chandan K. Reddy , Ping Wang , Dong Nie , Yue Ning

Electronic health records contain valuable information for monitoring patients' health trajectories over time. Disease progression models have been developed to understand the underlying patterns and dynamics of diseases using these data as…

Neural conversation models tend to generate safe, generic responses for most inputs. This is due to the limitations of likelihood-based decoding objectives in generation tasks with diverse outputs, such as conversation. To address this…

Computation and Language · Computer Science 2018-09-06 Ashutosh Baheti , Alan Ritter , Jiwei Li , Bill Dolan

Synthetic data generation is a promising solution to address privacy issues with the distribution of sensitive health data. Recently, diffusion models have set new standards for generative models for different data modalities. Also very…

Signal Processing · Electrical Eng. & Systems 2023-06-16 Juan Miguel Lopez Alcaraz , Nils Strodthoff

Researchers require timely access to real-world longitudinal electronic health records (EHR) to develop, test, validate, and implement machine learning solutions that improve the quality and efficiency of healthcare. In contrast, health…

Machine Learning · Computer Science 2020-12-21 Siddharth Biswal , Soumya Ghosh , Jon Duke , Bradley Malin , Walter Stewart , Jimeng Sun

Human reasoning can often be understood as an interplay between two systems: the intuitive and associative ("System 1") and the deliberative and logical ("System 2"). Neural sequence models -- which have been increasingly successful at…

Artificial Intelligence · Computer Science 2021-12-16 Maxwell Nye , Michael Henry Tessler , Joshua B. Tenenbaum , Brenden M. Lake

Synthetic data is a standard component in training large language models, yet systematic comparisons across design dimensions, including rephrasing strategy, generator model, and source data, remain absent. We conduct extensive controlled…

Electronic health records (EHRs) are long, noisy, and often redundant, posing a major challenge for the clinicians who must navigate them. Large language models (LLMs) offer a promising solution for extracting and reasoning over this…

Computation and Language · Computer Science 2025-08-21 Skatje Myers , Dmitriy Dligach , Timothy A. Miller , Samantha Barr , Yanjun Gao , Matthew Churpek , Anoop Mayampurath , Majid Afshar

As smart homes become increasingly prevalent, intelligent models are widely used for tasks such as anomaly detection and behavior prediction. These models are typically trained on static datasets, making them brittle to behavioral drift…

Artificial Intelligence · Computer Science 2025-08-06 Zhiyao Xu , Dan Zhao , Qingsong Zou , Qing Li , Yong Jiang , Yuhang Wang , Jingyu Xiao

Synchronous systems provide a basic model of embedded systems and industrial systems are modeled as Simulink diagrams and/or Lustre programs. Although the test generation problem is critical in the development of safe systems, it often…

Software Engineering · Computer Science 2021-12-13 Daisuke Ishii , Takashi Tomita , Kenji Onishi , Toshiaki Aoki