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Segmentation masks of pathological areas are useful in many medical applications, such as brain tumour and stroke management. Moreover, healthy counterfactuals of diseased images can be used to enhance radiologists' training files and to…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Alessandro Fontanella , Grant Mair , Joanna Wardlaw , Emanuele Trucco , Amos Storkey

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

Anomaly detection plays a vital role in industrial manufacturing. Due to the scarcity of real defect images, unsupervised approaches that rely solely on normal images have been extensively studied. Recently, diffusion-based generative…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Sungho Kang , Hyunkyu Park , Yeonho Lee , Hanbyul Lee , Mijoo Jeong , YeongHyeon Park , Injae Lee , Juneho Yi

Reconstruction-based methods have been commonly used for unsupervised anomaly detection, in which a normal image is reconstructed and compared with the given test image to detect and locate anomalies. Recently, diffusion models have shown…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Di Wu , Shicai Fan , Xue Zhou , Li Yu , Yuzhong Deng , Jianxiao Zou , Baihong Lin

Denoising diffusion probabilistic models (DDPMs) have been proven capable of synthesizing high-quality images with remarkable diversity when trained on large amounts of data. However, to our knowledge, few-shot image generation tasks have…

Computer Vision and Pattern Recognition · Computer Science 2023-03-08 Jingyuan Zhu , Huimin Ma , Jiansheng Chen , Jian Yuan

Few-shot anomaly detection streamlines and simplifies industrial safety inspection. However, limited samples make accurate differentiation between normal and abnormal features challenging, and even more so under category-agnostic…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Guangyao Zhai , Yue Zhou , Xinyan Deng , Lars Heckler , Nassir Navab , Benjamin Busam

Anomaly generation is often framed as few-shot fine-tuning with anomalous samples, which contradicts the scarcity that motivates generation and tends to overfit category priors. We tackle the setting where no real anomaly samples or…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Chaoran Xu , Chengkan Lv , Qiyu Chen , Yunkang Cao , Feng Zhang , Zhengtao Zhang

Unsupervised anomaly detection in brain images is crucial for identifying injuries and pathologies without access to labels. However, the accurate localization of anomalies in medical images remains challenging due to the inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Farzad Beizaee , Gregory Lodygensky , Christian Desrosiers , Jose Dolz

Recent advances in diffusion models have spurred research into their application for Reconstruction-based unsupervised anomaly detection. However, these methods may struggle with maintaining structural integrity and recovering the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Farzad Beizaee , Gregory A. Lodygensky , Christian Desrosiers , Jose Dolz

Time series anomaly detection (TSAD) has been an important area of research for decades, with reconstruction-based methods, mostly based on generative models, gaining popularity and demonstrating success. Diffusion models have recently…

Machine Learning · Computer Science 2026-03-02 Kohei Obata , Zheng Chen , Yasuko Matsubara , Lingwei Zhu , Yasushi Sakurai

Despite diffusion models' superior capabilities in modeling complex distributions, there are still non-trivial distributional discrepancies between generated and ground-truth images, which has resulted in several notable problems in image…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Yujian Liu , Yang Zhang , Tommi Jaakkola , Shiyu Chang

Denoising diffusion models are a powerful type of generative models used to capture complex distributions of real-world signals. However, their applicability is limited to scenarios where training samples are readily available, which is not…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Ayush Tewari , Tianwei Yin , George Cazenavette , Semon Rezchikov , Joshua B. Tenenbaum , Frédo Durand , William T. Freeman , Vincent Sitzmann

Detecting out-of-distribution (OOD) inputs is pivotal for deploying safe vision systems in open-world environments. We revisit diffusion models, not as generators, but as universal perceptual templates for OOD detection. This research…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Lemar Abdi , Amaan Valiuddin , Francisco Caetano , Christiaan Viviers , Fons van der Sommen

With the rise of generative models, there is a growing interest in unifying all tasks within a generative framework. Anomaly detection methods also fall into this scope and utilize diffusion models to generate or reconstruct normal samples…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Xiaofan Li , Xin Tan , Zhuo Chen , Zhizhong Zhang , Ruixin Zhang , Rizen Guo , Guannan Jiang , Yulong Chen , Yanyun Qu , Lizhuang Ma , Yuan Xie

Deep learning is widely applied in computer-aided pathological diagnosis, which alleviates the pathologist workload and provide timely clinical analysis. However, most models generally require large-scale annotated data for training, which…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Zeyu Liu , Tianyi Zhang , Yufang He , Yunlu Feng , Yu Zhao , Guanglei Zhang

Effectively addressing the challenge of industrial Anomaly Detection (AD) necessitates an ample supply of defective samples, a constraint often hindered by their scarcity in industrial contexts. This paper introduces a novel algorithm…

Computer Vision and Pattern Recognition · Computer Science 2024-03-27 Hanxi Li , Zhengxun Zhang , Hao Chen , Lin Wu , Bo Li , Deyin Liu , Mingwen Wang

The rapid advancements in machine learning have made its application to anomalous diffusion analysis both essential and inevitable. This review systematically introduces the integration of machine learning techniques for enhanced analysis…

Machine Learning · Computer Science 2025-04-01 Wenjie Cai , Yi Hu , Xiang Qu , Hui Zhao , Gongyi Wang , Jing Li , Zihan Huang

Reconstruction-based approaches have achieved remarkable outcomes in anomaly detection. The exceptional image reconstruction capabilities of recently popular diffusion models have sparked research efforts to utilize them for enhanced…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Haoyang He , Jiangning Zhang , Hongxu Chen , Xuhai Chen , Zhishan Li , Xu Chen , Yabiao Wang , Chengjie Wang , Lei Xie

We present a novel method for image anomaly detection, where algorithms that use samples drawn from some distribution of "normal" data, aim to detect out-of-distribution (abnormal) samples. Our approach includes a combination of encoder and…

Image and Video Processing · Electrical Eng. & Systems 2020-03-02 Nina Tuluptceva , Bart Bakker , Irina Fedulova , Anton Konushin

In medical imaging, the diffusion models have shown great potential for synthetic image generation tasks. However, these approaches often lack the interpretable connections between the generated and real images and can create anatomically…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Jian-Qing Zheng , Yuanhan Mo , Yang Sun , Jiahua Li , Fuping Wu , Ziyang Wang , Tonia Vincent , Bartłomiej W. Papież