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Modern wearable devices can conveniently record various biosignals in the many different environments of daily living, enabling a rich view of individual health. However, not all biosignals are the same: high-fidelity biosignals, such as…

Machine Learning · Computer Science 2025-02-03 Salar Abbaspourazad , Anshuman Mishra , Joseph Futoma , Andrew C. Miller , Ian Shapiro

Photoplethysmography (PPG)-based foundation models are gaining traction due to the widespread use of PPG in biosignal monitoring and their potential to generalize across diverse health applications. In this paper, we introduce Pulse-PPG,…

Machine Learning · Computer Science 2025-07-25 Mithun Saha , Maxwell A. Xu , Wanting Mao , Sameer Neupane , James M. Rehg , Santosh Kumar

Blood pressure (BP) is a key indicator of cardiovascular health. As hypertension remains a global cause of morbidity and mortality, accurate, continuous, and non-invasive BP monitoring is therefore of paramount importance.…

Signal Processing · Electrical Eng. & Systems 2025-10-20 Bálint Tóth , Dominik Senti , Thorir Mar Ingolfsson , Jeffrey Zweidler , Alexandre Elsig , Luca Benini , Yawei Li

Wearable devices record physiological and behavioral signals that can improve health predictions. While foundation models are increasingly used for such predictions, they have been primarily applied to low-level sensor data, despite…

Cardiac biosignals, such as electrocardiograms (ECG) and photoplethysmograms (PPG), are of paramount importance for the diagnosis, prevention, and management of cardiovascular diseases, and have been extensively used in a variety of…

Wearable foundation models have the potential to transform digital health by learning transferable representations from large-scale biosignals collected in everyday settings. While recent progress has been made in large-scale pretraining,…

While ubiquitous wearable sensors capture a wealth of behavioral and physiological information, effectively transforming these signals into personalized health insights is challenging. Specifically, converting low-level sensor data into…

Photoplethysmography (PPG) is the leading non-invasive technique for monitoring biosignals and cardiovascular health, with widespread adoption in both clinical settings and consumer wearable devices. While machine learning models trained on…

Machine Learning · Computer Science 2025-02-06 Arvind Pillai , Dimitris Spathis , Fahim Kawsar , Mohammad Malekzadeh

Cardiovascular disease remains the leading cause of global mortality, yet scalable cardiac monitoring is hindered by the gap between diagnostic-rich ECG and ubiquitous wearable PPG. Bridging this gap requires representations that are…

Machine Learning · Computer Science 2026-05-12 Zhangdaihong Liu , Chang Liu , Fenglin Liu , Yixuan Chen , Yang Yang , David A. Clifton , Xiao Gu

Advances in wearable computing and AI have increased interest in leveraging PPG for health monitoring over the past decade. One of the biggest challenges in developing health algorithms based on such biosignals is the sparsity of clinical…

Recent biosignal foundation models (FMs) have demonstrated promising performance across diverse clinical prediction tasks, yet systematic evaluation on long-duration multimodal data remains limited. We introduce SignalMC-MED, a benchmark…

Machine Learning · Computer Science 2026-03-11 Fredrik K. Gustafsson , Xiao Gu , Mattia Carletti , Patitapaban Palo , David W. Eyre , David A. Clifton

Cardiac abnormalities affecting heart rate and rhythm are commonly observed in both healthy and acutely unwell people. Although many of these are benign, they can sometimes indicate a serious health risk. ECG monitors are typically used to…

Signal Processing · Electrical Eng. & Systems 2018-07-12 Stewart Whiting , Samuel Moreland , Jason Costello , Glen Colopy , Christopher McCann

Photoplethysmography (PPG) is widely used as a non-invasive and accessible modality for continuous health monitoring. However, despite being a peripheral hemodynamic signal intrinsically coupled with systemic circulation, existing research…

Signal Processing · Electrical Eng. & Systems 2026-03-20 Guangkun Nie , Xiaocheng Fang , Gongzheng Tang , Yujie Xiao , Jun Li , Bo Liu , Hongyan Li , Shenda Hong

Background: Photoplethysmography (PPG) is a non-invasive optical sensing technique widely used to capture hemodynamic information, with broad deployment in both clinical monitoring systems and wearable devices. In recent years, the…

Artificial Intelligence · Computer Science 2026-05-06 Guangkun Nie , Jiabao Zhu , Gongzheng Tang , Deyun Zhang , Shijia Geng , Qinghao Zhao , Shenda Hong

Photoplethysmography (PPG) is one of the most widely captured biosignals for clinical prediction tasks, yet PPG-based algorithms are typically trained on small-scale datasets of uncertain quality, which hinders meaningful algorithm…

Machine Learning · Computer Science 2026-03-24 Mohammad Moulaeifard , Philip J. Aston , Peter H. Charlton , Nils Strodthoff

Photoplethysmography (PPG) is widely used in wearable health monitoring, yet large PPG foundation models remain difficult to deploy on resource-limited devices. We present PPG-Distill, a knowledge distillation framework that transfers both…

Machine Learning · Computer Science 2025-11-10 Juntong Ni , Saurabh Kataria , Shengpu Tang , Carl Yang , Xiao Hu , Wei Jin

Time-series foundation models excel at tasks like forecasting across diverse data types by leveraging informative waveform representations. Wearable sensing data, however, pose unique challenges due to their variability in patterns and…

Machine Learning · Computer Science 2025-05-19 Yunfei Luo , Yuliang Chen , Asif Salekin , Tauhidur Rahman

The successes of foundation models such as ChatGPT and AlphaFold have spurred significant interest in building similar models for electronic medical records (EMRs) to improve patient care and hospital operations. However, recent hype has…

Photoplethysmogram (PPG) and electrocardiogram (ECG) are commonly recorded in intesive care unit (ICU) and operating room (OR). However, the high incidence of poor, incomplete, and inconsistent signal quality, can lead to false alarms or…

Machine Learning · Computer Science 2025-09-16 Zongheng Guo , Tao Chen , Manuela Ferrario

Specialized foundation models are beginning to emerge in various medical subdomains, but pretraining methodologies and parametric scaling with the size of the pretraining dataset are rarely assessed systematically and in a like-for-like…

Signal Processing · Electrical Eng. & Systems 2026-05-13 M A Al-Masud , Nils Strodthoff
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