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Deep learning has been widely used for protein engineering. However, it is limited by the lack of sufficient experimental data to train an accurate model for predicting the functional fitness of high-order mutants. Here, we develop SESNet,…

Quantitative Methods · Quantitative Biology 2023-04-10 Mingchen Li , Liqi Kang , Yi Xiong , Yu Guang Wang , Guisheng Fan , Pan Tan , Liang Hong

As proteins with similar structures often have similar functions, analysis of protein structures can help predict protein functions and is thus important. We consider the problem of protein structure classification, which computationally…

Machine Learning · Statistics 2019-10-08 Hongyu Guo , Khalique Newaz , Scott Emrich , Tijana Milenkovic , Jun Li

In this paper we propose a novel augmentation technique that improves not only the performance of deep neural networks on clean test data, but also significantly increases their robustness to random transformations, both affine and…

Generative diffusion models offer a natural choice for data augmentation when training complex vision models. However, ensuring reliability of their generative content as augmentation samples remains an open challenge. Despite a number of…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Khawar Islam , Naveed Akhtar

The Mixup method (Zhang et al. 2018), which uses linearly interpolated data, has emerged as an effective data augmentation tool to improve generalization performance and the robustness to adversarial examples. The motivation is to curtail…

Machine Learning · Computer Science 2020-12-25 Minjin Kim , Young-geun Kim , Dongha Kim , Yongdai Kim , Myunghee Cho Paik

Data augmentation is a widely used training trick in deep learning to improve the network generalization ability. Despite many encouraging results, several recent studies did point out limitations of the conventional data augmentation…

Machine Learning · Computer Science 2020-10-06 Yi Xu , Asaf Noy , Ming Lin , Qi Qian , Hao Li , Rong Jin

Previous work showed empirically that large neural networks can be significantly reduced in size while preserving their accuracy. Model compression became a central research topic, as it is crucial for deployment of neural networks on…

Machine Learning · Computer Science 2020-01-06 Ben Mussay , Margarita Osadchy , Vladimir Braverman , Samson Zhou , Dan Feldman

Machine Learning methods have of late made significant efforts to solving multidisciplinary problems in the field of cancer classification using microarray gene expression data. Feature subset selection methods can play an important role in…

Computational Engineering, Finance, and Science · Computer Science 2013-03-04 G. Prat , Ll. Belanche

Our study investigates the impact of data augmentation on the performance of multivariate time series models, focusing on datasets from the UCR archive. Despite the limited size of these datasets, we achieved classification accuracy…

Machine Learning · Computer Science 2024-06-11 Romain Ilbert , Thai V. Hoang , Zonghua Zhang

Model compression techniques allow to significantly reduce the computational cost associated with data processing by deep neural networks with only a minor decrease in average accuracy. Simultaneously, reducing the model size may have a…

Machine Learning · Computer Science 2021-09-28 Sebastian Cygert , Andrzej Czyżewski

Anomaly detection under open-set scenario is a challenging task that requires learning discriminative fine-grained features to detect anomalies that were even unseen during training. As a cheap yet effective approach, data augmentation has…

Computer Vision and Pattern Recognition · Computer Science 2023-11-02 Jianan Ye , Yijie Hu , Xi Yang , Qiu-Feng Wang , Chao Huang , Kaizhu Huang

We present a method for expanding a dataset by incorporating knowledge from the wide distribution of pre-trained latent diffusion models. Data augmentations typically incorporate inductive biases about the image formation process into the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-13 Orest Kupyn , Christian Rupprecht

While deep learning holds great promise for disease diagnosis and prognosis in cardiac magnetic resonance imaging, its progress is often constrained by highly imbalanced and biased training datasets. To address this issue, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Grzegorz Skorupko , Richard Osuala , Zuzanna Szafranowska , Kaisar Kushibar , Vien Ngoc Dang , Nay Aung , Steffen E Petersen , Karim Lekadir , Polyxeni Gkontra

Over-parameterized deep neural networks have proven to be able to learn an arbitrary dataset with 100$\%$ training accuracy. Because of a risk of overfitting and computational cost issues, we cannot afford to increase the number of network…

Machine Learning · Computer Science 2019-04-08 Bukweon Kim , Sung Min Lee , Jin Keun Seo

We propose a novel algorithm for data augmentation in nonlinear over-parametrized regression. Our data augmentation algorithm borrows from the literature on causality and extends the recently proposed Anchor regression (AR) method for data…

Machine Learning · Computer Science 2023-11-29 Nora Schneider , Shirin Goshtasbpour , Fernando Perez-Cruz

ProBoost, a new boosting algorithm for probabilistic classifiers, is proposed in this work. This algorithm uses the epistemic uncertainty of each training sample to determine the most challenging/uncertain ones; the relevance of these…

Purpose: To allow fast and high-quality reconstruction of clinical accelerated multi-coil MR data by learning a variational network that combines the mathematical structure of variational models with deep learning. Theory and Methods:…

Computer Vision and Pattern Recognition · Computer Science 2017-04-04 Kerstin Hammernik , Teresa Klatzer , Erich Kobler , Michael P Recht , Daniel K Sodickson , Thomas Pock , Florian Knoll

In this work, we propose a data augmentation strategy aimed at improving the training phase of neural networks and, consequently, the accuracy of their predictions. Our approach relies on generating synthetic data through a suitable…

Numerical Analysis · Mathematics 2025-11-17 Giacomo Dimarco , Federica Ferrarese , Lorenzo Pareschi

Imbalanced regression arises when the target distribution is skewed, causing models to focus on dense regions and struggle with underrepresented (minority) samples. Despite its relevance across many applications, few methods have been…

Machine Learning · Computer Science 2025-08-05 Shayan Alahyari , Shiva Mehdipour Ghobadlou , Mike Domaratzki

3D softwares are now capable of producing highly realistic images that look nearly indistinguishable from the real images. This raises the question: can real datasets be enhanced with 3D rendered data? We investigate this question. In this…

Computer Vision and Pattern Recognition · Computer Science 2022-04-06 Shesh Narayan Gupta , Nicholas Bear Brown
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