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Recent advances in artificial intelligence, particularly large language models LLMs, have shown promising capabilities in transforming rare disease research. This survey paper explores the integration of LLMs in the analysis of rare…

Computation and Language · Computer Science 2025-05-26 Valentina Carbonari , Pierangelo Veltri , Pietro Hiram Guzzi

Large Language Models(LLMs)have become effective tools for natural language processing and have been used in many different fields. This essay offers a succinct summary of various LLM subcategories. The survey emphasizes recent developments…

Computation and Language · Computer Science 2023-07-21 Saurabh Pahune , Manoj Chandrasekharan

Large Language Models (LLMs) are increasingly applied to medical imaging tasks, including image interpretation and synthetic image generation. However, these models often produce hallucinations, which are confident but incorrect outputs…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Anindya Bijoy Das , Shahnewaz Karim Sakib , Shibbir Ahmed

Large Language Models (LLMs) have recently demonstrated remarkable performance in general tasks across various fields. However, their effectiveness within specific domains such as drug development remains challenges. To solve these…

Artificial Intelligence · Computer Science 2024-10-16 Tengfei Ma , Xuan Lin , Tianle Li , Chaoyi Li , Long Chen , Peng Zhou , Xibao Cai , Xinyu Yang , Daojian Zeng , Dongsheng Cao , Xiangxiang Zeng

In the domain of data science, the predictive tasks of classification, regression, and imputation of missing values are commonly encountered challenges associated with tabular data. This research endeavors to apply Large Language Models…

Machine Learning · Computer Science 2026-04-23 Yazheng Yang , Yuqi Wang , Yaxuan Li , Sankalok Sen , Lei Li , Lin Qiu , Qi Liu

Recent breakthroughs in large language models (LLMs) offer unprecedented natural language understanding and generation capabilities. However, existing surveys on LLMs in biomedicine often focus on specific applications or model…

Large Language Models (LLMs) have exhibited remarkable capabilities in clinical scenarios. Despite their potential, existing works face challenges when applying LLMs to medical settings. Strategies relying on training with medical datasets…

Computation and Language · Computer Science 2025-10-10 Keer Lu , Zheng Liang , Da Pan , Shusen Zhang , Guosheng Dong , Zhonghai Wu , Huang Leng , Bin Cui , Wentao Zhang

We present Clinical Prediction with Large Language Models (CPLLM), a method that involves fine-tuning a pre-trained Large Language Model (LLM) for clinical disease and readmission prediction. We utilized quantization and fine-tuned the LLM…

Computation and Language · Computer Science 2024-05-03 Ofir Ben Shoham , Nadav Rappoport

Multimodal large language models (MLLMs) show promising performance on medical visual question answering (VQA) and report generation, but these generation and explanation abilities do not reliably transfer to disease-specific…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Li Wang , Xi Chen , XiangWen Deng , HuaHui Yi , ZeKun Jiang , Kang Li , Jian Li

Large Language Models (LLMs) have demonstrated exceptional proficiency in text understanding and embedding tasks. However, their potential in multimodal representation, particularly for item-to-item (I2I) recommendations, remains…

Information Retrieval · Computer Science 2025-01-22 Chao Zhang , Haoxin Zhang , Shiwei Wu , Di Wu , Tong Xu , Xiangyu Zhao , Yan Gao , Yao Hu , Enhong Chen

Large language models (LLMs) are a class of language models that have demonstrated outstanding performance across a range of natural language processing (NLP) tasks and have become a highly sought-after research area, because of their…

Digital Libraries · Computer Science 2023-04-06 Lizhou Fan , Lingyao Li , Zihui Ma , Sanggyu Lee , Huizi Yu , Libby Hemphill

Frontier large language models (LLMs), such as GPT-5, Claude 4.5, Gemini 3, Llama 4, and DeepSeek-R1, represent a transformative class of AI tools capable of revolutionizing various aspects of healthcare by generating human-like responses…

In the face of rapidly expanding online medical literature, automated systems for aggregating and summarizing information are becoming increasingly crucial for healthcare professionals and patients. Large Language Models (LLMs), with their…

Computation and Language · Computer Science 2024-03-07 Niraj Yagnik , Jay Jhaveri , Vivek Sharma , Gabriel Pila

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

Logs are important in modern software development with runtime information. Log parsing is the first step in many log-based analyses, that involve extracting structured information from unstructured log data. Traditional log parsers face…

Software Engineering · Computer Science 2024-04-30 Zeyang Ma , An Ran Chen , Dong Jae Kim , Tse-Hsun Chen , Shaowei Wang

Materials discovery and development are critical for addressing global challenges. Yet, the exponential growth in materials science literature comprising vast amounts of textual data has created significant bottlenecks in knowledge…

This position paper analyzes the evolving roles of open-source and closed-source large language models (LLMs) in healthcare, emphasizing their distinct contributions and the scientific community's response to their development. Due to their…

Computers and Society · Computer Science 2025-01-20 Jiawei Xu , Ying Ding , Yi Bu

Language is essentially a complex, intricate system of human expressions governed by grammatical rules. It poses a significant challenge to develop capable AI algorithms for comprehending and grasping a language. As a major approach,…

Large language models (LLMs), such as GPT4 and LLaMA, are creating significant advancements in natural language processing, due to their strong text encoding/decoding ability and newly found emergent capability (e.g., reasoning). While LLMs…

Computation and Language · Computer Science 2024-11-22 Bowen Jin , Gang Liu , Chi Han , Meng Jiang , Heng Ji , Jiawei Han

Large Language Models (LLMs) have become valuable assets in mental health, showing promise in both classification tasks and counseling applications. This paper offers a perspective on using LLMs in mental health applications. It discusses…

Computation and Language · Computer Science 2023-12-19 Shaoxiong Ji , Tianlin Zhang , Kailai Yang , Sophia Ananiadou , Erik Cambria