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The detection of lesions in magnetic resonance imaging (MRI)-scans of human brains remains challenging, time-consuming and error-prone. Recently, unsupervised anomaly detection (UAD) methods have shown promising results for this task. These…

Image and Video Processing · Electrical Eng. & Systems 2022-04-13 Finn Behrendt , Marcel Bengs , Frederik Rogge , Julia Krüger , Roland Opfer , Alexander Schlaefer

Generative models have demonstrated significant success in anomaly detection and segmentation over the past decade. Recently, diffusion models have emerged as a powerful alternative, outperforming previous approaches such as GANs and VAEs.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Mehrdad Moradi , Marco Grasso , Bianca Maria Colosimo , Kamran Paynabar

Anomaly detection has garnered extensive applications in real industrial manufacturing due to its remarkable effectiveness and efficiency. However, previous generative-based models have been limited by suboptimal reconstruction quality,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Hui Zhang , Zheng Wang , Dan Zeng , Zuxuan Wu , Yu-Gang Jiang

Anomaly detection (AD) is the identification of data samples that do not fit a learned data distribution. As such, AD systems can help physicians to determine the presence, severity, and extension of a pathology. Deep generative models,…

Image and Video Processing · Electrical Eng. & Systems 2021-04-12 Jaime Simarro , Ezequiel de la Rosa , Thijs Vande Vyvere , David Robben , Diana M. Sima

Anomaly detection in medical imaging plays a crucial role in identifying pathological regions across various imaging modalities, such as brain MRI, liver CT, and carotid ultrasound (US). However, training fully supervised segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yuan Bi , Lucie Huang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab , Zhongliang Jiang

Due to the diversity of brain anatomy and the scarcity of annotated data, supervised anomaly detection for brain MRI remains challenging, driving the development of unsupervised anomaly detection (UAD) approaches. Current UAD methods…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Hao Li , Zhenfeng Zhuang , Jingyu Lin , Yu Liu , Yifei Chen , Qiong Peng , Lequan Yu , Liansheng Wang

T2 hyperintensities in spinal cord MR images are crucial biomarkers for conditions such as degenerative cervical myelopathy. However, current clinical diagnoses primarily rely on manual evaluation. Deep learning methods have shown promise…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Qi Zhang , Xiuyuan Chen , Ziyi He , Kun Wang , Lianming Wu , Hongxing Shen , Jianqi Sun

Unsupervised Anomalous Sound Detection (ASD) aims to design a generalizable method that can be used to detect anomalies when only normal sounds are given. In this paper, Anomalous Sound Detection based on Diffusion Models (ASD-Diffusion) is…

Sound · Computer Science 2024-09-25 Fengrun Zhang , Xiang Xie , Kai Guo

Unsupervised Anomaly Detection (UAD) methods aim to identify anomalies in test samples comparing them with a normative distribution learned from a dataset known to be anomaly-free. Approaches based on generative models offer…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Sergio Naval Marimont , Vasilis Siomos , Matthew Baugh , Christos Tzelepis , Bernhard Kainz , Giacomo Tarroni

Recent advances in diffusion models have spurred research into their application for Reconstruction-based unsupervised anomaly detection. However, these methods may struggle with maintaining structural integrity and recovering the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Farzad Beizaee , Gregory A. Lodygensky , Christian Desrosiers , Jose Dolz

Anomaly detection in medical imaging is a challenging task in contexts where abnormalities are not annotated. This problem can be addressed through unsupervised anomaly detection (UAD) methods, which identify features that do not match with…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Geoffroy Oudoumanessah , Carole Lartizien , Michel Dojat , Florence Forbes

Unsupervised anomaly detection (UAD) aims to detect anomalies without labeled data, a necessity in many machine learning applications where anomalous samples are rare or not available. Most state-of-the-art methods fall into two categories:…

Machine Learning · Computer Science 2025-07-30 Nicolas Pinon , Carole Lartizien

Pathological brain lesions exhibit diverse appearance in brain images, in terms of intensity, texture, shape, size, and location. Comprehensive sets of data and annotations are difficult to acquire. Therefore, unsupervised anomaly detection…

Diffusion magnetic resonance imaging (dMRI) is a crucial technique in neuroimaging studies, allowing for the non-invasive probing of the underlying structures of brain tissues. Clinical dMRI data is susceptible to various artifacts during…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Sheng Chen , Zihao Tang , Xinyi Wang , Chenyu Wang , Weidong Cai

Unsupervised anomaly segmentation aims to detect patterns that are distinct from any patterns processed during training, commonly called abnormal or out-of-distribution patterns, without providing any associated manual segmentations. Since…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 Ziyun Liang , Harry Anthony , Felix Wagner , Konstantinos Kamnitsas

Reconstruction-based approaches have achieved remarkable outcomes in anomaly detection. The exceptional image reconstruction capabilities of recently popular diffusion models have sparked research efforts to utilize them for enhanced…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Haoyang He , Jiangning Zhang , Hongxu Chen , Xuhai Chen , Zhishan Li , Xu Chen , Yabiao Wang , Chengjie Wang , Lei Xie

In medical applications, weakly supervised anomaly detection methods are of great interest, as only image-level annotations are required for training. Current anomaly detection methods mainly rely on generative adversarial networks or…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Julia Wolleb , Florentin Bieder , Robin Sandkühler , Philippe C. Cattin

Detection of various lesions in brain MRI is clinically critical, but challenging due to the diversity of lesions and variability in imaging conditions. Current unsupervised learning methods detect anomalies mainly through reconstructing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Tao Yang , Xiuying Wang , Hao Liu , Guanzhong Gong , Lian-Ming Wu , Yu-Ping Wang , Lisheng Wang

Deep unsupervised anomaly detection in brain magnetic resonance imaging offers a promising route to identify pathological deviations without requiring lesion-specific annotations. Yet, fragmented evaluations, heterogeneous datasets, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Alexander Frotscher , Christian F. Baumgartner , Thomas Wolfers

Unsupervised anomaly detection and segmentation methods train a model to learn the training distribution as `normal'. In the testing phase, they identify patterns that deviate from this normal distribution as `anomalies'. To learn the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Ziyun Liang , Xiaoqing Guo , Wentian Xu , Yasin Ibrahim , Natalie Voets , Pieter M Pretorius , J. Alison Noble , Konstantinos Kamnitsas