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Use of medical data, also known as electronic health records, in research helps develop and advance medical science. However, protecting patient confidentiality and identity while using medical data for analysis is crucial. Medical data can…

Artificial Intelligence · Computer Science 2018-10-17 Vithya Yogarajan , Michael Mayo , Bernhard Pfahringer

Electronic Health Records (EHRs) have become the primary form of medical data-keeping across the United States. Federal law restricts the sharing of any EHR data that contains protected health information (PHI). De-identification, the…

Computation and Language · Computer Science 2021-03-26 Abdullah Ahmed , Adeel Abbasi , Carsten Eickhoff

Clinical notes often describe the most important aspects of a patient's physiology and are therefore critical to medical research. However, these notes are typically inaccessible to researchers without prior removal of sensitive protected…

Computation and Language · Computer Science 2018-03-08 Willie Boag , Tristan Naumann , Peter Szolovits

Background: Natural Language Processing (NLP) is widely used to extract clinical insights from Electronic Health Records (EHRs). However, the lack of annotated data, automated tools, and other challenges hinder the full utilisation of NLP…

Computation and Language · Computer Science 2023-06-23 Elias Hossain , Rajib Rana , Niall Higgins , Jeffrey Soar , Prabal Datta Barua , Anthony R. Pisani , Ph. D , Kathryn Turner}

De-identification is the process of removing 18 protected health information (PHI) from clinical notes in order for the text to be considered not individually identifiable. Recent advances in natural language processing (NLP) has allowed…

Computation and Language · Computer Science 2018-10-04 Kaung Khin , Philipp Burckhardt , Rema Padman

De-identification of electronic health records (EHR) is a vital step towards advancing health informatics research and maximising the use of available data. It is a two-step process where step one is the identification of protected health…

Computers and Society · Computer Science 2020-02-18 Vithya Yogarajan , Bernhard Pfahringer , Michael Mayo

The objective of this study is to address the critical issue of de-identification of clinical reports in order to allow access to data for research purposes, while ensuring patient privacy. The study highlights the difficulties faced in…

Computation and Language · Computer Science 2023-03-24 Xavier Tannier , Perceval Wajsbürt , Alice Calliger , Basile Dura , Alexandre Mouchet , Martin Hilka , Romain Bey

De-identification is the task of detecting protected health information (PHI) in medical text. It is a critical step in sanitizing electronic health records (EHRs) to be shared for research. Automatic de-identification classifierscan…

Computation and Language · Computer Science 2019-06-13 Max Friedrich , Arne Köhn , Gregor Wiedemann , Chris Biemann

Objective: to provide a scoping review of papers on clinical natural language processing (NLP) tasks that use publicly available electronic health record data from a cohort of patients. Materials and Methods: We searched six databases,…

The robust development of Electronic Health Records (EHRs) causes a significant growth in sharing EHRs for clinical research. However, such a sharing makes it difficult to protect patient's privacy. A number of automated de-identification…

Cryptography and Security · Computer Science 2012-11-19 Jie Qian , Nafees Qamar

Unstructured textual data is at the heart of healthcare systems. For obvious privacy reasons, these documents are not accessible to researchers as long as they contain personally identifiable information. One way to share this data while…

Cryptography and Security · Computer Science 2022-11-03 Yakini Tchouka , Jean-François Couchot , David Laiymani

Clinical trial eligibility matching is a critical yet often labor-intensive and error-prone step in medical research, as it ensures that participants meet precise criteria for safe and reliable study outcomes. Recent advances in Natural…

Machine Learning · Computer Science 2025-03-04 Muhammad Talha Sharif , Abdul Rehman

Background: Clinical natural language processing (NLP) refers to the use of computational methods for extracting, processing, and analyzing unstructured clinical text data, and holds a huge potential to transform healthcare in various…

Objective: This review aims to analyze the application of natural language processing (NLP) techniques in cancer research using electronic health records (EHRs) and clinical notes. This review addresses gaps in the existing literature by…

Computation and Language · Computer Science 2025-02-05 Muhammad Bilal , Ameer Hamza , Nadia Malik

Objective: Patient notes in electronic health records (EHRs) may contain critical information for medical investigations. However, the vast majority of medical investigators can only access de-identified notes, in order to protect the…

Computation and Language · Computer Science 2016-06-14 Franck Dernoncourt , Ji Young Lee , Ozlem Uzuner , Peter Szolovits

Background: More than half (57%) of pharma clinical research spend is in support of clinical trials. One reason is that Electronic Health Record (EHR) systems and HIPAA privacy rules often limit how broadly patient information can be…

Quantitative Methods · Quantitative Biology 2018-07-03 Andrew J McMurry , Richen Zhang , Alex Foxman , Lawrence Reiter , Ronny Schnel , DeLeys Brandman

The paper presents a systematic review of state-of-the-art approaches to identify patient cohorts using electronic health records. It gives a comprehensive overview of the most commonly de-tected phenotypes and its underlying data sets.…

Machine Learning · Statistics 2017-07-25 Norman Hiob , Stefan Lessmann

Automated deidentification of clinical text data is crucial due to the high cost of manual deidentification, which has been a barrier to sharing clinical text and the advancement of clinical natural language processing. However, creating…

Computation and Language · Computer Science 2023-11-07 Callandra Moore , Jonathan Ranisau , Walter Nelson , Jeremy Petch , Alistair Johnson

Free-text clinical notes detail all aspects of patient care and have great potential to facilitate quality improvement and assurance initiatives as well as advance clinical research. However, concerns about patient privacy and…

Computation and Language · Computer Science 2021-02-23 Nicholas Dobbins , David Wayne , Kahyun Lee , Özlem Uzuner , Meliha Yetisgen

De-identification in the healthcare setting is an application of NLP where automated algorithms are used to remove personally identifying information of patients (and, sometimes, providers). With the recent rise of generative large language…

Computation and Language · Computer Science 2025-09-19 Kiana Aghakasiri , Noopur Zambare , JoAnn Thai , Carrie Ye , Mayur Mehta , J. Ross Mitchell , Mohamed Abdalla
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