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Segmentation is an important analysis task for biomedical images, enabling the study of individual organelles, cells or organs. Deep learning has massively improved segmentation methods, but challenges remain in generalization to new…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Carolin Teuber , Anwai Archit , Constantin Pape

Weakly supervised semantic segmentation (WSSS) aims to bypass the need for laborious pixel-level annotation by using only image-level annotation. Most existing methods rely on Class Activation Maps (CAM) to derive pixel-level pseudo-labels…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Tianle Chen , Zheda Mai , Ruiwen Li , Wei-lun Chao

Few-Shot Semantic Segmentation (FSS) focuses on segmenting novel object categories from only a handful of annotated examples. Most existing approaches rely on extensive episodic training to learn transferable representations, which is both…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yi-Jen Tsai , Yen-Yu Lin , Chien-Yao Wang

Medical image segmentation often faces the challenge of prohibitively expensive annotation costs. While few-shot learning offers a promising solution to alleviate this burden, conventional approaches still rely heavily on pre-training with…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Jie Xu , Xiaokang Li , Chengyu Yue , Yuanyuan Wang , Yi Guo

The Segment Anything Model (SAM) has drawn significant attention from researchers who work on medical image segmentation because of its generalizability. However, researchers have found that SAM may have limited performance on medical…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Yihao Liu , Jiaming Zhang , Andres Diaz-Pinto , Haowei Li , Alejandro Martin-Gomez , Amir Kheradmand , Mehran Armand

Segmentation models such as Segment Anything Model (SAM) and SAM2 achieve strong prompt-driven zero-shot performance. However, their training on natural images limits domain transfer to medical data. Consequently, accurate segmentation…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Tal Grossman , Noa Cahan , Lev Ayzenberg , Hayit Greenspan

The emergence of large foundation models has propelled significant advances in various domains. The Segment Anything Model (SAM), a leading model for image segmentation, exemplifies these advances, outperforming traditional methods.…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Saurabh Yadav , Avi Gupta , Koteswar Rao Jerripothula

Segment Anything Model (SAM) has received remarkable attention as it offers a powerful and versatile solution for object segmentation in images. However, fine-tuning SAM for downstream segmentation tasks under different scenarios remains a…

Computer Vision and Pattern Recognition · Computer Science 2023-12-19 Zelin Peng , Zhengqin Xu , Zhilin Zeng , Xiaokang Yang , Wei Shen

Segment Anything Model (SAM) is a foundation model for semantic segmentation and shows excellent generalization capability with the prompts. In this empirical study, we investigate the robustness and zero-shot generalizability of the SAM in…

Image and Video Processing · Electrical Eng. & Systems 2023-05-01 An Wang , Mobarakol Islam , Mengya Xu , Yang Zhang , Hongliang Ren

Semantic segmentation is a critical step in automated image interpretation and analysis where pixels are classified into one or more predefined semantically meaningful classes. Deep learning approaches for semantic segmentation rely on…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Tushar Kataria , Beatrice Knudsen , Shireen Elhabian

The Segment Anything Model (SAM) family has become a widely adopted vision foundation model, but its ability to control segmentation granularity remains limited. Users often need to refine results manually - by adding more prompts or…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Junwei Yu , Trevor Darrell , XuDong Wang

Although SAM-based single-source domain generalization models for medical image segmentation can mitigate the impact of domain shift on the model in cross-domain scenarios, these models still face two major challenges. First, the…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Huanli Zhuo , Leilei Ma , Haifeng Zhao , Shiwei Zhou , Dengdi Sun , Yanping Fu

The Segment Anything Model (SAM) has exhibited outstanding performance in various image segmentation tasks. Despite being trained with over a billion masks, SAM faces challenges in mask prediction quality in numerous scenarios, especially…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Zhaozhi Xie , Bochen Guan , Weihao Jiang , Muyang Yi , Yue Ding , Hongtao Lu , Lei Zhang

Fully supervised deep learning (DL) models for surgical video segmentation have been shown to struggle with non-adversarial, real-world corruptions of image quality including smoke, bleeding, and low illumination. Foundation models for…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Yiqing Shen , Hao Ding , Xinyuan Shao , Mathias Unberath

Collective intelligence from multiple medical experts consistently surpasses individual expertise in clinical diagnosis, particularly for ambiguous medical image segmentation tasks involving unclear tissue boundaries or pathological…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Mingzhou Jiang , Jiaying Zhou , Junde Wu , Tianyang Wang , Yueming Jin , Min Xu

We introduce the Segment Anything (SA) project: a new task, model, and dataset for image segmentation. Using our efficient model in a data collection loop, we built the largest segmentation dataset to date (by far), with over 1 billion…

Computer Vision and Pattern Recognition · Computer Science 2023-04-06 Alexander Kirillov , Eric Mintun , Nikhila Ravi , Hanzi Mao , Chloe Rolland , Laura Gustafson , Tete Xiao , Spencer Whitehead , Alexander C. Berg , Wan-Yen Lo , Piotr Dollár , Ross Girshick

The recent wave of foundation models has witnessed tremendous success in computer vision (CV) and beyond, with the segment anything model (SAM) having sparked a passion for exploring task-agnostic visual foundation models. Empowered by its…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Chunhui Zhang , Yawen Cui , Weilin Lin , Guanjie Huang , Yan Rong , Li Liu , Shiguang Shan

The Segment-Anything Model (SAM) is a vision foundation model for segmentation with a prompt-driven framework. SAM generates class-agnostic masks based on user-specified instance-referring prompts. However, adapting SAM for automated…

Computer Vision and Pattern Recognition · Computer Science 2024-11-22 Hussni Mohd Zakir , Eric Tatt Wei Ho

Recent advances in vision foundation models, such as the Segment Anything Model (SAM) and its successor SAM2, have achieved state-of-the-art performance on general image segmentation benchmarks. However, these models struggle in adverse…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Dharsan Ravindran , Kevin Wang , Zhuoyuan Cao , Saleh Abdelrahman , Jeffery Wu

The Segment Anything Model (SAM) represents a significant breakthrough into foundation models for computer vision, providing a large-scale image segmentation model. However, despite SAM's zero-shot performance, its segmentation masks lack…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Xianjie Liu , Keren Fu , Yao Jiang , Qijun Zhao