Related papers: Interpretable Mechanistic Representations for Meal…
We present and critically discuss five commonly used mathematical models of the meal glucose rate of appearance in humans. Such models are key to simulation of the metabolism in healthy people, people with diabetes, and obese people, and…
Autonomous driving presents a complex challenge, which is usually addressed with artificial intelligence models that are end-to-end or modular in nature. Within the landscape of modular approaches, a bio-inspired neural circuit policy model…
Consumption of diets with low glycemic impact is highly recommended for diabetics and pre-diabetics as it helps maintain their blood glucose levels. However, laboratory analysis of dietary glycemic potency is time-consuming and expensive.…
Many real-world problems require reasoning across multiple scales, demanding models which operate not on single data points, but on entire distributions. We introduce generative distribution embeddings (GDE), a framework that lifts…
Learning Interpretable representation in medical applications is becoming essential for adopting data-driven models into clinical practice. It has been recently shown that learning a disentangled feature representation is important for a…
The paper describes the interaction design of a hand-held interface supporting the self-management of Type 1 diabetes. It addresses well-established clinical and human-computer interaction requirements. The design exploits three…
Multiplex Imaging (MI) enables the simultaneous visualization of multiple biological markers in separate imaging channels at subcellular resolution, providing valuable insights into cell-type heterogeneity and spatial organization. However,…
As AI-based medical devices are becoming more common in imaging fields like radiology and histology, interpretability of the underlying predictive models is crucial to expand their use in clinical practice. Existing heatmap-based…
Control of blood glucose is essential for diabetes management. Current digital therapeutic approaches for subjects with Type 1 diabetes mellitus (T1DM) such as the artificial pancreas and insulin bolus calculators leverage machine learning…
Unsupervised learning allows us to leverage unlabelled data, which has become abundantly available, and to create embeddings that are usable on a variety of downstream tasks. However, the typical lack of interpretability of unsupervised…
Distributed representations of medical concepts have been used to support downstream clinical tasks recently. Electronic Health Records (EHR) capture different aspects of patients' hospital encounters and serve as a rich source for…
Drug repositioning is an attractive cost-efficient strategy for the development of treatments for human diseases. Here, we propose an interpretable model that learns disease self-representations for drug repositioning. Our…
Type 1 Diabetes is a chronic autoimmune condition in which the immune system attacks and destroys insulin-producing beta cells in the pancreas, resulting in little to no insulin production. Insulin helps glucose in your blood enter your…
We propose an automated genomic interpretation module that transforms raw DNA sequences into actionable, interpretable decisions suitable for integration into medical automation and robotic systems. Our framework combines Chaos Game…
Detecting an ingestion environment is an important aspect of monitoring dietary intake. It provides insightful information for dietary assessment. However, it is a challenging problem where human-based reviewing can be tedious, and…
In this paper we investigate the use of model-based reinforcement learning to assist people with Type 1 Diabetes with insulin dose decisions. The proposed architecture consists of multiple Echo State Networks to predict blood glucose levels…
Pretrained encoders for mathematical texts have achieved significant improvements on various tasks such as formula classification and information retrieval. Yet they remain limited in representing and capturing student strategies for entire…
The research explores a novel mathematical model for closed loop insulin delivery systems, featuring a glucose sensitive membrane. It employs a sophisticated framework of nonlinear reaction diffusion equations and enzyme kinetics. Central…
Transformer-based models have become state-of-the-art tools in various machine learning tasks, including time series classification, yet their complexity makes understanding their internal decision-making challenging. Existing…
The prevalence of Diabetes mellitus (DM) in the Middle East is exceptionally high as compared to the rest of the world. In fact, the prevalence of diabetes in the Middle East is 17-20%, which is well above the global average of 8-9%.…