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The development of generative models in the past decade has allowed for hyperrealistic data synthesis. While potentially beneficial, this synthetic data generation process has been relatively underexplored in cancer histopathology. One…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Aakash Madhav Rao , Debayan Gupta

Objective: While recent advances in text-conditioned generative models have enabled the synthesis of realistic medical images, progress has been largely confined to 2D modalities such as chest X-rays. Extending text-to-image generation to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Daniele Molino , Camillo Maria Caruso , Filippo Ruffini , Paolo Soda , Valerio Guarrasi

Augmentation for dense prediction typically relies on either sample mixing or generative synthesis. Mixing improves robustness but misaligned masks yield soft label ambiguity. Diffusion synthesis increases apparent diversity but, when…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Pengyu Jie , Wanquan Liu , Rui He , Yihui Wen , Deyu Meng , Chenqiang Gao

The text-to-image synthesis by diffusion models has recently shown remarkable performance in generating high-quality images. Although performs well for simple texts, the models may get confused when faced with complex texts that contain…

Computer Vision and Pattern Recognition · Computer Science 2024-01-15 Chang Yu , Junran Peng , Xiangyu Zhu , Zhaoxiang Zhang , Qi Tian , Zhen Lei

Diffusion-based generative models have shown promise in synthesizing histopathology images to address data scarcity caused by privacy constraints. Diagnostic text reports provide high-level semantic descriptions, and masks offer…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Mahesh Bhosale , Abdul Wasi , Yuanhao Zhai , Yunjie Tian , Samuel Border , Nan Xi , Pinaki Sarder , Junsong Yuan , David Doermann , Xuan Gong

By decomposing the image formation process into a sequential application of denoising autoencoders, diffusion models (DMs) achieve state-of-the-art synthesis results on image data and beyond. Additionally, their formulation allows for a…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Robin Rombach , Andreas Blattmann , Dominik Lorenz , Patrick Esser , Björn Ommer

Multi-modal foundation models are typically trained on millions of pairs of natural images and text captions, frequently obtained through web-crawling approaches. Although such models depict excellent generative capabilities, they do not…

Computer Vision and Pattern Recognition · Computer Science 2023-01-03 Pierre Chambon , Christian Bluethgen , Curtis P. Langlotz , Akshay Chaudhari

We generate synthetic images with the "Stable Diffusion" image generation model using the Wordnet taxonomy and the definitions of concepts it contains. This synthetic image database can be used as training data for data augmentation in…

Computer Vision and Pattern Recognition · Computer Science 2022-11-07 Andreas Stöckl

Text-conditioned generative models for volumetric medical imaging provide semantic control but lack explicit anatomical guidance, often resulting in outputs that are spatially ambiguous or anatomically inconsistent. In contrast,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Daniele Molino , Camillo Maria Caruso , Paolo Soda , Valerio Guarrasi

Flow matching and diffusion models have shown impressive results in text-to-image generation, producing photorealistic images through an iterative denoising process. A common strategy to speed up synthesis is to perform early denoising at…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Jyun-Ze Tang , Chih-Fan Hsu , Jeng-Lin Li , Ming-Ching Chang , Wei-Chao Chen

Diffusion-based models have achieved state-of-the-art performance on text-to-image synthesis tasks. However, one critical limitation of these models is the low fidelity of generated images with respect to the text description, such as…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Qiucheng Wu , Yujian Liu , Handong Zhao , Trung Bui , Zhe Lin , Yang Zhang , Shiyu Chang

Deep learning-based image generation has seen significant advancements with diffusion models, notably improving the quality of generated images. Despite these developments, generating images with unseen characteristics beneficial for…

Diffusion models have recently achieved astonishing performance in generating high-fidelity photo-realistic images. Given their huge success, it is still unclear whether synthetic images are applicable for knowledge distillation when real…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Zheng Li , Yuxuan Li , Penghai Zhao , Renjie Song , Xiang Li , Jian Yang

Latent diffusion models (LDMs) dominate high-quality image generation, yet integrating representation learning with generative modeling remains a challenge. We introduce a novel generative image modeling framework that seamlessly bridges…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Theodoros Kouzelis , Efstathios Karypidis , Ioannis Kakogeorgiou , Spyros Gidaris , Nikos Komodakis

Controllable image synthesis models allow creation of diverse images based on text instructions or guidance from a reference image. Recently, denoising diffusion probabilistic models have been shown to generate more realistic imagery than…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Xihui Liu , Dong Huk Park , Samaneh Azadi , Gong Zhang , Arman Chopikyan , Yuxiao Hu , Humphrey Shi , Anna Rohrbach , Trevor Darrell

Image generation models trained on large datasets can synthesize high-quality images but often produce spatially inconsistent and distorted images due to limited information about the underlying structures and spatial layouts. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Hyundo Lee , Suhyung Choi , Inwoo Hwang , Byoung-Tak Zhang

In this research, we introduce an innovative method for synthesizing medical images using generative adversarial networks (GANs). Our proposed GANs method demonstrates the capability to produce realistic synthetic images even when trained…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Yinqiu Feng , Bo Zhang , Lingxi Xiao , Yutian Yang , Tana Gegen , Zexi Chen

Diffusion models are able to generate photorealistic images in arbitrary scenes. However, when applying diffusion models to image translation, there exists a trade-off between maintaining spatial structure and high-quality content. Besides,…

Computer Vision and Pattern Recognition · Computer Science 2023-02-07 Shiqi Sun , Shancheng Fang , Qian He , Wei Liu

In the medical domain, acquiring large datasets is challenging due to both accessibility issues and stringent privacy regulations. Consequently, data availability and privacy protection are major obstacles to applying machine learning in…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Wenwu Tang , Khaled Seyam , Bin Yang

Medical imaging plays a vital role in modern diagnostics and treatment. The temporal nature of disease or treatment progression often results in longitudinal data. Due to the cost and potential harm, acquiring large medical datasets…

Computer Vision and Pattern Recognition · Computer Science 2023-01-16 Julian Schön , Raghavendra Selvan , Lotte Nygård , Ivan Richter Vogelius , Jens Petersen