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High-throughput sequencing (HTS) technologies have revolutionized the field of genomics, enabling rapid and cost-effective genome analysis for various applications. However, the increasing volume of genomic data generated by HTS…

Hardware Architecture · Computer Science 2023-06-01 Onur Mutlu , Can Firtina

Multiple genome alignment remains a challenging problem. Effects of recombination including rearrangement, segmental duplication, gain, and loss can create a mosaic pattern of homology even among closely related organisms. We describe a…

Genomics · Quantitative Biology 2009-11-02 Aaron E. Darling , Bob Mau , Nicole T. Perna

Classification is one of the most important tasks in Machine Learning (ML) and with recent advancements in artificial intelligence (AI) it is important to find efficient ways to implement it. Generally, the choice of classification…

Machine Learning · Computer Science 2023-12-27 Anuja Dixit , Shreya Byreddy , Guanqun Song , Ting Zhu

The linked cell list algorithm is an essential part of molecular simulation software, both molecular dynamics and Monte Carlo. Though it scales linearly with the number of particles, there has been a constant interest in increasing its…

Computational Physics · Physics 2013-03-19 Ulrich Welling , Guido Germano

In genomics, pattern matching against a sequence of nucleotides plays a pivotal role for DNA sequence alignment and comparing genomes. This helps tackling some diseases, such as cancer in humans. The complexity of searching biological…

Quantitative Methods · Quantitative Biology 2017-10-04 Fereshte Mozafari , Hossein Babashah , Somayyeh Koohi , Zahra Kavehvash

Machine learning algorithms have enabled computers to predict things by learning from previous data. The data storage and processing power are increasing rapidly, thus increasing machine learning and Artificial intelligence applications.…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-09-14 Muhammad Fahad Saleem

Genomic data sets are growing dramatically as the cost of sequencing continues to decline and small sequencing devices become available. Enormous community databases store and share this data with the research community, but some of these…

Since the release of human genome sequences, one of the most important research issues is about indexing the genome sequences, and the suffix tree is most widely adopted for that purpose. The traditional suffix tree construction algorithms…

Databases · Computer Science 2015-05-20 Woong-Kee Loh , Yang-Sae Moon , Wookey Lee

This work proposes a novel approach to evaluate and analyze the behavior of multi-population parallel genetic algorithms (PGAs) when running on a cluster of multi-core processors. In particular, we deeply study their numerical and…

Neural and Evolutionary Computing · Computer Science 2025-08-05 Tomohiro Harada , Enrique Alba , Gabriel Luque

Most machine learning algorithms are configured by one or several hyperparameters that must be carefully chosen and often considerably impact performance. To avoid a time consuming and unreproducible manual trial-and-error process to find…

Genomic signal processing has been used successfully in bioinformatics to analyze biomolecular sequences and gain varied insights into DNA structure, gene organization, protein binding, sequence evolution, etc. But challenges remain in…

Genomics · Quantitative Biology 2022-11-04 Saish Jaiswal , Shreya Nema , Hema A Murthy , Manikandan Narayanan

Sorting is one of the most basic algorithms, and developing highly parallel sorting programs is becoming increasingly important in high-performance computing because the number of CPU cores per node in modern supercomputers tends to…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-09-08 Tomoyuki Tokuue , Tomoaki Ishiyama

Scientific investigations that incorporate next generation sequencing involve analyses of high-dimensional data where the need to organize, collate and interpret the outcomes are pressingly important. Currently, data can be collected at the…

Machine Learning · Statistics 2016-08-01 Stephen T Rush , Christine H Lee , Washington Mio , Peter T Kim

Multiple Sequences Alignment (MSA) of biological sequences is a fundamental problem in computational biology due to its critical significance in wide ranging applications including haplotype reconstruction, sequence homology, phylogenetic…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-05-13 Fahad Saeed , Ashfaq Khokhar

Multiple signal classification algorithm (MUSICAL) provides a super-resolution microscopy method. In the previous research, MUSICAL has enabled data-parallelism well on a desktop computer or a Linux-based server. However, the running time…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-06-14 Quan Do , Jon Ivar Kristiansen , Krishna Agarwal , Phuong Hoai Ha

Sequence alignment forms an important backbone in many sequencing applications. A commonly used strategy for sequence alignment is an approximate string matching with a two-dimensional dynamic programming approach. Although some prior work…

Databases · Computer Science 2023-01-24 Seongyeon Park , Hajin Kim , Tanveer Ahmad , Nauman Ahmed , Zaid Al-Ars , H. Peter Hofstee , Youngsok Kim , Jinho Lee

One of the most critical issues in machine learning is the selection of appropriate hyper parameters for training models. Machine learning models may be able to reach the best training performance and may increase the ability to generalize…

Machine Learning · Computer Science 2023-02-23 Caner Erden , Halil Ibrahim Demir , Abdullah Hulusi Kökçam

This work presents a comparison for the performance of sequential sorting algorithms under four different modes of execution, the sequential processing mode, a conventional multi-threading implementation, multi-threading with OpenMP Library…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-09-07 Mohammad Fasha

Design of printed circuit board (PCB) stack-up requires the consideration of characteristic impedance, insertion loss and crosstalk. As there are many parameters in a PCB stack-up design, the optimization of these parameters needs to be…

Other Statistics · Statistics 2019-11-12 Jiayi He , Aravind Sampath Kumar , Arun Chada , Bhyrav Mutnury , James Drewniak

Sorting is one of the most fundamental problems in the field of computer science. With the rapid development of manycore processors, it shows great importance to design efficient parallel sort algorithm on manycore architecture. This paper…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-02-18 Tianyi Yu , Wei Li