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As machine learning methods gain prominence within clinical decision-making, addressing fairness concerns becomes increasingly urgent. Despite considerable work dedicated to detecting and ameliorating algorithmic bias, today's methods are…

Machine Learning · Computer Science 2023-08-01 Charles Jones , Daniel C. Castro , Fabio De Sousa Ribeiro , Ozan Oktay , Melissa McCradden , Ben Glocker

The rapid advancements in artificial intelligence (AI) have revolutionized smart healthcare, driving innovations in wearable technologies, continuous monitoring devices, and intelligent diagnostic systems. However, security, explainability,…

Machine Learning · Computer Science 2024-10-02 Prasenjit Maji , Amit Kumar Mondal , Hemanta Kumar Mondal , Saraju P. Mohanty

Deep neural networks excel in medical imaging but remain prone to biases, leading to fairness gaps across demographic groups. We provide the first systematic exploration of Human-AI alignment and fairness in this domain. Our results show…

Computer Vision and Pattern Recognition · Computer Science 2025-05-16 Haozhe Luo , Ziyu Zhou , Zixin Shu , Aurélie Pahud de Mortanges , Robert Berke , Mauricio Reyes

Artificial intelligence (AI) systems increasingly achieve expert-level predictive accuracy in healthcare, yet improvements in model performance often fail to produce corresponding gains in patient outcomes. We term this disconnect the…

Artificial Intelligence · Computer Science 2026-01-13 Rifa Ferzana

We propose Causal Interaction Trees for identifying subgroups of participants that have enhanced treatment effects using observational data. We extend the Classification and Regression Tree algorithm by using splitting criteria that focus…

Methodology · Statistics 2021-12-08 Jiabei Yang , Issa J. Dahabreh , Jon A. Steingrimsson

Context: This study explores how software professionals identify and address biases in AI systems within the software industry, focusing on practical knowledge and real-world applications. Goal: We aimed to understand the strategies…

Software Engineering · Computer Science 2024-09-05 Ronnie de Souza Santos , Luiz Fernando de Lima , Maria Teresa Baldassarre , Rodrigo Spinola

Sepsis is a severe condition responsible for many deaths in the United States and worldwide, making accurate prediction of outcomes crucial for timely and effective treatment. Previous studies employing machine learning faced limitations in…

Machine Learning · Computer Science 2025-01-03 Arseniy Shumilov , Yueting Zhu , Negin Ashrafi , Armin Abdollahi , Greg Placencia , Kamiar Alaei , Maryam Pishgar

The use of artificial intelligence (AI) in healthcare has become a very active research area in the last few years. While significant progress has been made in image classification tasks, only a few AI methods are actually being deployed in…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Ramon Correa , Jiwoong Jason Jeong , Bhavik Patel , Hari Trivedi , Judy W. Gichoya , Imon Banerjee

Decision trees are powerful machine learning algorithms, widely used in fields such as economics and medicine for their simplicity and interpretability. However, decision trees such as CART are prone to overfitting, especially when grown…

Machine Learning · Statistics 2026-01-13 Likun Zhang , Wei Ma

In the fight against hard-to-treat diseases such as cancer, it is often difficult to discover new treatments that benefit all subjects. For regulatory agency approval, it is more practical to identify subgroups of subjects for whom the…

Methodology · Statistics 2014-10-09 Wei-Yin Loh , Xu He , Michael Man

Artificial Intelligence (AI) is now firmly at the center of evidence-based medicine. Despite many success stories that edge the path of AI's rise in healthcare, there are comparably many reports of significant shortcomings and unexpected…

Aim: provide a methodological framework for the process of clinical tests, clinical acceptance, and scientific assessment of algorithms and software based on the artificial intelligence (AI) technologies. Clinical tests are considered as a…

Datasets can be biased due to societal inequities, human biases, under-representation of minorities, etc. Our goal is to certify that models produced by a learning algorithm are pointwise-robust to potential dataset biases. This is a…

Machine Learning · Computer Science 2021-10-12 Anna P. Meyer , Aws Albarghouthi , Loris D'Antoni

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

As Artificial Intelligence (AI) making advancements in medical decision-making, there is a growing need to ensure doctors develop appropriate reliance on AI to avoid adverse outcomes. However, existing methods in enabling appropriate AI…

Deep neural networks are increasingly employed in high-stakes medical applications, despite their tendency for shortcut learning in the presence of spurious correlations, which can have potentially fatal consequences in practice. Whereas a…

Artificial Intelligence · Computer Science 2025-07-30 Frederik Pahde , Thomas Wiegand , Sebastian Lapuschkin , Wojciech Samek

Fairness and accountability are two essential pillars for trustworthy Artificial Intelligence (AI) in healthcare. However, the existing AI model may be biased in its decision marking. To tackle this issue, we propose an adversarial…

Computer Vision and Pattern Recognition · Computer Science 2021-05-12 Xiaoxiao Li , Ziteng Cui , Yifan Wu , Lin Gu , Tatsuya Harada

In an era where artificial intelligence and machine learning algorithms increasingly impact human life, it is crucial to develop models that account for potential discrimination in their predictions. This paper tackles this problem by…

Machine Learning · Statistics 2024-10-10 Anna Gottard , Vanessa Verrina , Sabrina Giordano

Medical AI algorithms can often experience degraded performance when evaluated on previously unseen sites. Addressing cross-site performance disparities is key to ensuring that AI is equitable and effective when deployed on diverse patient…

Machine Learning · Computer Science 2021-11-17 Eric Wu , Kevin Wu , James Zou