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We consider the problem of building high-level, class-specific feature detectors from only unlabeled data. For example, is it possible to learn a face detector using only unlabeled images? To answer this, we train a 9-layered locally…

Machine Learning · Computer Science 2017-04-17 Quoc V. Le , Marc'Aurelio Ranzato , Rajat Monga , Matthieu Devin , Kai Chen , Greg S. Corrado , Jeff Dean , Andrew Y. Ng

Schizophrenia is a chronic neuropsychiatric disorder that causes distinct structural alterations within the brain. We hypothesize that deep learning applied to a structural neuroimaging dataset could detect disease-related alteration and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Junhao Zhang , Vishwanatha M. Rao , Ye Tian , Yanting Yang , Nicolas Acosta , Zihan Wan , Pin-Yu Lee , Chloe Zhang , Lawrence S. Kegeles , Scott A. Small , Jia Guo

Anomaly detection and localization in medical images is a challenging task, especially when the anomaly exhibits a change of existing structures, e.g., brain atrophy or changes in the pleural space due to pleural effusions. In this work, we…

Image and Video Processing · Electrical Eng. & Systems 2020-07-29 Julia Wolleb , Robin Sandkühler , Philippe C. Cattin

Anomaly detection plays a key role in industrial manufacturing for product quality control. Traditional methods for anomaly detection are rule-based with limited generalization ability. Recent methods based on supervised deep learning are…

Computer Vision and Pattern Recognition · Computer Science 2021-07-22 Ning Li , Kaitao Jiang , Zhiheng Ma , Xing Wei , Xiaopeng Hong , Yihong Gong

Camouflaged Object Detection (COD) is a challenging task in computer vision due to the high similarity between camouflaged objects and their surroundings. Existing COD methods primarily employ semantic segmentation, which suffers from…

Computer Vision and Pattern Recognition · Computer Science 2023-05-30 Zhongxi Chen , Ke Sun , Xianming Lin , Rongrong Ji

In biomedical and neurodegenerative disorders, accurate and early disease identification remains challenging due to the scarcity of labeled data and the complexity of imaging patterns. To address these challenges, we introduce ARMA-C3, a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 VSS Tejaswi Abburi , Saurabh J. Shigwan , Nitin Kumar

We propose a novel framework for Alzheimer's disease (AD) detection using brain MRIs. The framework starts with a data augmentation method called Brain-Aware Replacements (BAR), which leverages a standard brain parcellation to replace…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Mehmet Saygın Seyfioğlu , Zixuan Liu , Pranav Kamath , Sadjyot Gangolli , Sheng Wang , Thomas Grabowski , Linda Shapiro

So-called unsupervised anomaly detection is better described as semi-supervised, as it assumes all training data are nominal. This assumption simplifies training but requires manual data curation, introducing bias and limiting adaptability.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Muhammad Aqeel , Shakiba Sharifi , Marco Cristani , Francesco Setti

Lesion detection in brain Magnetic Resonance Images (MRIs) remains a challenging task. MRIs are typically read and interpreted by domain experts, which is a tedious and time-consuming process. Recently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Marcel Bengs , Finn Behrendt , Max-Heinrich Laves , Julia Krüger , Roland Opfer , Alexander Schlaefer

Unsupervised learning can discover various unseen abnormalities, relying on large-scale unannotated medical images of healthy subjects. Towards this, unsupervised methods reconstruct a 2D/3D single medical image to detect outliers either in…

Computer Vision and Pattern Recognition · Computer Science 2020-10-13 Changhee Han , Leonardo Rundo , Kohei Murao , Tomoyuki Noguchi , Yuki Shimahara , Zoltan Adam Milacski , Saori Koshino , Evis Sala , Hideki Nakayama , Shinichi Satoh

Anomaly detection is the problem of recognizing abnormal inputs based on the seen examples of normal data. Despite recent advances of deep learning in recognizing image anomalies, these methods still prove incapable of handling complex…

Computer Vision and Pattern Recognition · Computer Science 2021-09-14 Nina Shvetsova , Bart Bakker , Irina Fedulova , Heinrich Schulz , Dmitry V. Dylov

Detecting anomalies in electrocardiogram data is crucial to identifying deviations from normal heartbeat patterns and providing timely intervention to at-risk patients. Various AutoEncoder models (AE) have been proposed to tackle the…

Machine Learning · Computer Science 2023-10-10 Giacomo Verardo , Magnus Boman , Samuel Bruchfeld , Marco Chiesa , Sabine Koch , Gerald Q. Maguire , Dejan Kostic

Semi-supervised learning has made significant strides in the medical domain since it alleviates the heavy burden of collecting abundant pixel-wise annotated data for semantic segmentation tasks. Existing semi-supervised approaches enhance…

Computer Vision and Pattern Recognition · Computer Science 2021-12-03 Xu Zheng , Chong Fu , Haoyu Xie , Jialei Chen , Xingwei Wang , Chiu-Wing Sham

Detection of various lesions in brain MRI is clinically critical, but challenging due to the diversity of lesions and variability in imaging conditions. Current unsupervised learning methods detect anomalies mainly through reconstructing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Tao Yang , Xiuying Wang , Hao Liu , Guanzhong Gong , Lian-Ming Wu , Yu-Ping Wang , Lisheng Wang

Anomaly detection in medical imaging is to distinguish the relevant biomarkers of diseases from those of normal tissues. Deep supervised learning methods have shown potentials in various detection tasks, but its performances would be…

Image and Video Processing · Electrical Eng. & Systems 2021-12-01 Byungjai Kim , Kinam Kwon , Changheun Oh , Hyunwook Park

In real-world clinical practice, overlooking unanticipated findings can result in serious consequences. However, supervised learning, which is the foundation for the current success of deep learning, only encourages models to identify…

Current unsupervised anomaly localization approaches rely on generative models to learn the distribution of normal images, which is later used to identify potential anomalous regions derived from errors on the reconstructed images. However,…

Image and Video Processing · Electrical Eng. & Systems 2021-10-29 Julio Silva-Rodríguez , Valery Naranjo , Jose Dolz

Unsupervised Out-of-Distribution (OOD) detection consists in identifying anomalous regions in images leveraging only models trained on images of healthy anatomy. An established approach is to tokenize images and model the distribution of…

Computer Vision and Pattern Recognition · Computer Science 2023-08-04 Sergio Naval Marimont , Vasilis Siomos , Giacomo Tarroni

Automatic segmentation of brain abnormalities is challenging, as they vary considerably from one pathology to another. Current methods are supervised and require numerous annotated images for each pathology, a strenuous task. To tackle…

Image and Video Processing · Electrical Eng. & Systems 2021-01-27 Benjamin Lambert , Maxime Louis , Senan Doyle , Florence Forbes , Michel Dojat , Alan Tucholka

In the field of healthcare, precise skin lesion segmentation is crucial for the early detection and accurate diagnosis of skin diseases. Despite significant advances in deep learning for image processing, existing methods have yet to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Siyu Wang , Hua Wang , Huiyu Li , Fan Zhang
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