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There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

Human doctors with well-structured medical knowledge can diagnose a disease merely via a few conversations with patients about symptoms. In contrast, existing knowledge-grounded dialogue systems often require a large number of dialogue…

Computation and Language · Computer Science 2020-12-23 Shuai Lin , Pan Zhou , Xiaodan Liang , Jianheng Tang , Ruihui Zhao , Ziliang Chen , Liang Lin

Medical AI, including clinical language models, vision-language models, and multimodal health record models, already summarizes notes, answers questions, and supports decisions. Their adaptation to new populations, specialties, or care…

Artificial Intelligence · Computer Science 2025-12-01 Michelle M. Li , Ben Y. Reis , Adam Rodman , Tianxi Cai , Noa Dagan , Ran D. Balicer , Joseph Loscalzo , Isaac S. Kohane , Marinka Zitnik

The medical conversational system can relieve the burden of doctors and improve the efficiency of healthcare, especially during the pandemic. This paper presents a medical conversational question answering (CQA) system based on the…

Computation and Language · Computer Science 2025-03-26 Fei Xia , Bin Li , Yixuan Weng , Shizhu He , Kang Liu , Bin Sun , Shutao Li , Jun Zhao

Large language models (LLMs) have shown amazing capabilities in knowledge memorization and the present. However, when it comes to domain-specific knowledge and downstream tasks like medical, general LLMs are often unable to give precise…

Computation and Language · Computer Science 2024-06-06 Maojun Sun

Medical Visual Question Answering (Med-VQA) represents a critical and challenging subtask within the general VQA domain. Despite significant advancements in general VQA, multimodal large language models (MLLMs) still exhibit substantial…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Hongyu Ge , Longkun Hao , Zihui Xu , Zhenxin Lin , Bin Li , Shoujun Zhou , Hongjin Zhao , Yihang Liu

Multimodal search-based dialogue is a challenging new task: It extends visually grounded question answering systems into multi-turn conversations with access to an external database. We address this new challenge by learning a neural…

Computation and Language · Computer Science 2018-11-22 Shubham Agarwal , Ondrej Dusek , Ioannis Konstas , Verena Rieser

The burgeoning size of Large Language Models (LLMs) has led to enhanced capabilities in generating responses, albeit at the expense of increased inference times and elevated resource demands. Existing methods of acceleration, predominantly…

Computation and Language · Computer Science 2024-05-31 Yao Yao , Zuchao Li , Hai Zhao

Generative Artificial Intelligence (AI), because of its emergent abilities, has empowered various fields, one typical of which is large language models (LLMs). One of the typical application fields of Generative AI is large language models…

Computation and Language · Computer Science 2024-02-12 Yan Zhao , Zhongyun Li , Yushan Pan , Jiaxing Wang , Yihong Wang

Two types of knowledge, triples from knowledge graphs and texts from documents, have been studied for knowledge aware open-domain conversation generation, in which graph paths can narrow down vertex candidates for knowledge selection…

Artificial Intelligence · Computer Science 2019-09-04 Zhibin Liu , Zheng-Yu Niu , Hua Wu , Haifeng Wang

The development of large language models (LLMs) has brought unprecedented possibilities for artificial intelligence (AI) based medical diagnosis. However, the application perspective of LLMs in real diagnostic scenarios is still unclear…

Computation and Language · Computer Science 2024-05-21 Zhoujian Sun , Cheng Luo , Ziyi Liu , Zhengxing Huang

Existing knowledge-grounded dialogue systems typically use finetuned versions of a pretrained language model (LM) and large-scale knowledge bases. These models typically fail to generalize on topics outside of the knowledge base, and…

Computation and Language · Computer Science 2022-03-17 Zihan Liu , Mostofa Patwary , Ryan Prenger , Shrimai Prabhumoye , Wei Ping , Mohammad Shoeybi , Bryan Catanzaro

Extractive question answering (QA) systems can enable physicians and researchers to query medical records, a foundational capability for designing clinical studies and understanding patient medical history. However, building these systems…

Computation and Language · Computer Science 2023-12-07 Joel Stremmel , Ardavan Saeedi , Hamid Hassanzadeh , Sanjit Batra , Jeffrey Hertzberg , Jaime Murillo , Eran Halperin

Extracting medical knowledge from healthcare texts enhances downstream tasks like medical knowledge graph construction and clinical decision-making. However, the construction and application of knowledge extraction models lack automation,…

Artificial Intelligence · Computer Science 2023-10-05 Hongxin Ding , Peinie Zou , Zhiyuan Wang , Junfeng Zhao , Yasha Wang , Qiang Zhou

Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2026-04-09 Nusrat Sultana , Abdullah Muhammad Moosa , Kazi Afzalur Rahman , Sajal Chandra Banik

Foundation models are becoming valuable tools in medicine. Yet despite their promise, the best way to leverage Large Language Models (LLMs) in complex medical tasks remains an open question. We introduce a novel multi-agent framework, named…

Computation and Language · Computer Science 2024-10-31 Yubin Kim , Chanwoo Park , Hyewon Jeong , Yik Siu Chan , Xuhai Xu , Daniel McDuff , Hyeonhoon Lee , Marzyeh Ghassemi , Cynthia Breazeal , Hae Won Park

Beyond current conversational chatbots or task-oriented dialogue systems that have attracted increasing attention, we move forward to develop a dialogue system for automatic medical diagnosis that converses with patients to collect…

Computation and Language · Computer Science 2019-03-19 Lin Xu , Qixian Zhou , Ke Gong , Xiaodan Liang , Jianheng Tang , Liang Lin

Medical visual question answering (Med-VQA) is a crucial multimodal task in clinical decision support and telemedicine. Recent methods fail to fully leverage domain-specific medical knowledge, making it difficult to accurately associate…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Xianyao Zheng , Hong Yu , Hui Cui , Changming Sun , Xiangyu Li , Ran Su , Leyi Wei , Jia Zhou , Junbo Wang , Qiangguo Jin

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

Current AI approaches have frequently been used to help personalize many aspects of medical experiences and tailor them to a specific individuals' needs. However, while such systems consider medically-relevant information, they ignore…

Artificial Intelligence · Computer Science 2019-07-31 Mor Vered , Frank Dignum , Tim Miller