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We present an investigation into diffusion models for molecular generation, with the aim of better understanding how their predictions compare to the results of physics-based calculations. The investigation into these models is driven by…

Diffusion models generate high-quality synthetic data. They operate by defining a continuous-time forward process which gradually adds Gaussian noise to data until fully corrupted. The corresponding reverse process progressively "denoises"…

RNA design shows growing applications in synthetic biology and therapeutics, driven by the crucial role of RNA in various biological processes. A fundamental challenge is to find functional RNA sequences that satisfy given structural…

Biomolecules · Quantitative Biology 2024-04-18 Han Huang , Ziqian Lin , Dongchen He , Liang Hong , Yu Li

Despite advances in diffusion-based text-to-music (TTM) methods, efficient, high-quality generation remains a challenge. We introduce Presto!, an approach to inference acceleration for score-based diffusion transformers via reducing both…

Diffusion models are widely recognized for generating high-quality and diverse images, but their poor real-time performance has led to numerous acceleration works, primarily focusing on UNet-based structures. With the more successful…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Pengtao Chen , Mingzhu Shen , Peng Ye , Jianjian Cao , Chongjun Tu , Christos-Savvas Bouganis , Yiren Zhao , Tao Chen

Recent progress in image-to-video (I2V) diffusion models has significantly advanced the field of generative inbetweening, which aims to generate semantically plausible frames between two keyframes. In particular, inference-time sampling…

Computer Vision and Pattern Recognition · Computer Science 2026-02-20 Wooseok Jeon , Seunghyun Shin , Dongmin Shin , Hae-Gon Jeon

Recent literature has effectively leveraged diffusion models trained on continuous variables as priors for solving inverse problems. Notably, discrete diffusion models with discrete latent codes have shown strong performance, particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Naoki Murata , Chieh-Hsin Lai , Yuhta Takida , Toshimitsu Uesaka , Bac Nguyen , Stefano Ermon , Yuki Mitsufuji

Diffusion models have become the go-to method for many generative tasks, particularly for image-to-image generation tasks such as super-resolution and inpainting. Current diffusion-based methods do not provide statistical guarantees…

Computer Vision and Pattern Recognition · Computer Science 2022-11-18 Eliahu Horwitz , Yedid Hoshen

Generative machine learning models are increasingly being used to design novel proteins for therapeutic and biotechnological applications. However, the current methods mostly focus on the design of proteins with a fixed backbone structure,…

Biomolecules · Quantitative Biology 2025-03-04 Petr Kouba , Joan Planas-Iglesias , Jiri Damborsky , Jiri Sedlar , Stanislav Mazurenko , Josef Sivic

Recent trends show recognition accuracy increasing even more profoundly. Inference process of Deep Convolutional Neural Networks (DCNN) has a large number of parameters, requires a large amount of computation, and can be very slow. The…

Computer Vision and Pattern Recognition · Computer Science 2017-09-15 Ryuji Kamiya , Takayoshi Yamashita , Mitsuru Ambai , Ikuro Sato , Yuji Yamauchi , Hironobu Fujiyoshi

Generative models, particularly diffusion models, have made significant success in data synthesis across various modalities, including images, videos, and 3D assets. However, current diffusion models are computationally intensive, often…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Yuanzhi Zhu , Hanshu Yan , Huan Yang , Kai Zhang , Junnan Li

Continuous visual autoregressive (AR) models have demonstrated promising performance in image generation. However, the heavy autoregressive inference burden imposes significant overhead. In Large Language Models (LLMs), speculative decoding…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Zili Wang , Robert Zhang , Kun Ding , Qi Yang , Fei Li , Shiming Xiang

Despite the remarkable generation capabilities of Diffusion Models (DMs), conducting training and inference remains computationally expensive. Previous works have been devoted to accelerating diffusion sampling, but achieving data-efficient…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Yize Li , Yihua Zhang , Sijia Liu , Xue Lin

Denoising Diffusion Probabilistic Models (DDPMs) have achieved impressive performance on various generation tasks. By modeling the reverse process of gradually diffusing the data distribution into a Gaussian distribution, generating a…

Computer Vision and Pattern Recognition · Computer Science 2022-05-31 Zhaoyang Lyu , Xudong XU , Ceyuan Yang , Dahua Lin , Bo Dai

For time-critical IoT applications using deep learning, inference acceleration through distributed computing is a promising approach to meet a stringent deadline. In this paper, we implement a working prototype of a new distributed…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Zhongtian Dong , Nan Li , Alexandros Iosifidis , Qi Zhang

Ensembles of Deep Neural Networks (DNNs) have achieved qualitative predictions but they are computing and memory intensive. Therefore, the demand is growing to make them answer a heavy workload of requests with available computational…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-08-31 Pierrick Pochelu , Serge G. Petiton , Bruno Conche

Latent Diffusion models (LDMs) have achieved remarkable results in synthesizing high-resolution images. However, the iterative sampling process is computationally intensive and leads to slow generation. Inspired by Consistency Models (song…

Computer Vision and Pattern Recognition · Computer Science 2023-10-09 Simian Luo , Yiqin Tan , Longbo Huang , Jian Li , Hang Zhao

Ultrasound reflection tomography is widely used to image large complex specimens that are only accessible from a single side, such as well systems and nuclear power plant containment walls. Typical methods for inverting the measurement rely…

Image and Video Processing · Electrical Eng. & Systems 2018-10-01 Hani Almansouri , S. V. Venkatakrishnan , Gregery T. Buzzard , Charles A. Bouman , Hector Santos-Villalobos

Large pretrained diffusion models have significantly enhanced the quality of generated videos, and yet their use in real-time streaming remains limited. Autoregressive models offer a natural framework for sequential frame synthesis but…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Jinxiu Liu , Xuanming Liu , Kangfu Mei , Yandong Wen , Ming-Hsuan Yang , Weiyang Liu

In recent years, motion generative models have undergone significant advancement, yet pose challenges in aligning with downstream objectives. Recent studies have shown that using differentiable rewards to directly align the preference of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Xiaofeng Tan , Wanjiang Weng , Haodong Lei , Hongsong Wang
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