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Multi-modal large language models (MLLMs) have demonstrated remarkable success in vision and visual-language tasks within the natural image domain. Owing to the significant diversities between the natural and remote sensing (RS) images, the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Wei Zhang , Miaoxin Cai , Tong Zhang , Yin Zhuang , Xuerui Mao

Recent medical multimodal foundation models are built as multimodal LLMs (MLLMs) by connecting a CLIP-pretrained vision encoder to an LLM using LLaVA-style finetuning. This two-stage, decoupled approach introduces a projection layer that…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Ashwin Kumar , Robbie Holland , Corey Barrett , Jangwon Kim , Maya Varma , Zhihong Chen , Yunhe Gao , Greg Zaharchuk , Tara Taghavi , Krishnaram Kenthapadi , Akshay Chaudhari

Large vision language models (VLMs) have progressed incredibly from research to applicability for general-purpose use cases. LLaVA-Med, a pioneering large language and vision assistant for biomedicine, can perform multi-modal biomedical…

Medical image segmentation is crucial for clinical diagnosis, yet existing models are limited by their reliance on explicit human instructions and lack the active reasoning capabilities to understand complex clinical questions. While recent…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Yu Huang , Zelin Peng , Yichen Zhao , Piao Yang , Xiaokang Yang , Wei Shen

Multimodal Large Language Model (MLLM) has recently garnered attention as a prominent research focus. By harnessing powerful LLM, it facilitates a transition of conversational generative AI from unimodal text to performing multimodal tasks.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Xuechen Guo , Wenhao Chai , Shi-Yan Li , Gaoang Wang

Multimodal Large Language Models (MLLMs) have achieved notable success in enhancing translation performance by integrating multimodal information. However, existing research primarily focuses on image-guided methods, whose applicability is…

Computation and Language · Computer Science 2026-03-04 Yexing Du , Youcheng Pan , Zekun Wang , Zheng Chu , Yichong Huang , Kaiyuan Liu , Bo Yang , Yang Xiang , Ming Liu , Bing Qin

Medical imaging provides essential visual insights for diagnosis, and multimodal large language models (MLLMs) are increasingly utilized for its analysis due to their strong generalization capabilities; however, the underlying factors…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Zhenyang Cai , Junying Chen , Rongsheng Wang , Weihong Wang , Yonglin Deng , Dingjie Song , Yize Chen , Zixu Zhang , Benyou Wang

CLIP and BiomedCLIP are examples of vision-language foundation models and offer strong cross-modal embeddings; however, they are not optimized for fine-grained medical retrieval tasks, such as retrieving clinically relevant radiology…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Zhaohui Liang , Sivaramakrishnan Rajaraman , Niccolo Marini , Zhiyun Xue , Sameer Antani

Connecting text and visual modalities plays an essential role in generative intelligence. For this reason, inspired by the success of large language models, significant research efforts are being devoted to the development of Multimodal…

Computer Vision and Pattern Recognition · Computer Science 2024-06-07 Davide Caffagni , Federico Cocchi , Luca Barsellotti , Nicholas Moratelli , Sara Sarto , Lorenzo Baraldi , Lorenzo Baraldi , Marcella Cornia , Rita Cucchiara

Large Language Models (LLMs) represent a class of deep learning models adept at understanding natural language and generating coherent responses to various prompts or queries. These models far exceed the complexity of conventional neural…

Machine Learning · Computer Science 2024-12-05 Minghao Shao , Abdul Basit , Ramesh Karri , Muhammad Shafique

The global demand for radiologists is increasing rapidly due to a growing reliance on medical imaging services, while the supply of radiologists is not keeping pace. Advances in computer vision and image processing technologies present…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Shehroz S. Khan , Petar Przulj , Ahmed Ashraf , Ali Abedi

Large vision-language models (VLMs) have evolved from general-purpose applications to specialized use cases such as in the clinical domain, demonstrating potential for decision support in radiology. One promising application is assisting…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Zhifan Jiang , Dong Yang , Vishwesh Nath , Abhijeet Parida , Nishad P. Kulkarni , Ziyue Xu , Daguang Xu , Syed Muhammad Anwar , Holger R. Roth , Marius George Linguraru

In recent years, multimodal large language models (MLLMs) have made significant strides by training on vast high-quality image-text datasets, enabling them to generally understand images well. However, the inherent difficulty in explicitly…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Yuanze Lin , Yunsheng Li , Dongdong Chen , Weijian Xu , Ronald Clark , Philip Torr , Lu Yuan

Multi-modal large language models (MLLMs) have shown impressive capabilities as a general-purpose interface for various visual and linguistic tasks. However, building a unified MLLM for multi-task learning in the medical field remains a…

Computer Vision and Pattern Recognition · Computer Science 2024-11-04 Xun Zhu , Ying Hu , Fanbin Mo , Miao Li , Ji Wu

Several medical Multimodal Large Languange Models (MLLMs) have been developed to address tasks involving visual images with textual instructions across various medical modalities, achieving impressive results. Most current medical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Lehan Wang , Haonan Wang , Honglong Yang , Jiaji Mao , Zehong Yang , Jun Shen , Xiaomeng Li

The integration of deep learning-based glaucoma detection with large language models (LLMs) presents an automated strategy to mitigate ophthalmologist shortages and improve clinical reporting efficiency. However, applying general LLMs to…

Multiagent Systems · Computer Science 2025-12-18 Philip R. Liu , Sparsh Bansal , Jimmy Dinh , Aditya Pawar , Ramani Satishkumar , Shail Desai , Neeraj Gupta , Xin Wang , Shu Hu

Medical Visual Question Answering (Med-VQA) represents a critical and challenging subtask within the general VQA domain. Despite significant advancements in general VQA, multimodal large language models (MLLMs) still exhibit substantial…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Hongyu Ge , Longkun Hao , Zihui Xu , Zhenxin Lin , Bin Li , Shoujun Zhou , Hongjin Zhao , Yihang Liu

Vision-Language Models (VLMs), such as CLIP, have demonstrated remarkable zero-shot capabilities in various computer vision tasks. However, their application to medical imaging remains challenging due to the high variability and complexity…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Xusheng Liang , Lihua Zhou , Nianxin Li , Miao Xu , Ziyang Song , Dong Yi , Jinlin Wu , Jiawei Ma , Hongbin Liu , Zhen Lei , Jiebo Luo

Accurate and interpretable multi-disease diagnosis remains a critical challenge in medical research, particularly when leveraging heterogeneous multimodal medical data. Current approaches often rely on single-modal data, limiting their…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Yuting Zhang , Kaishen Yuan , Hao Lu , Yutao Yue , Jintai Chen , Kaishun Wu

Longitudinal chest X-ray (CXR) interpretation requires reasoning over disease evolution across multiple patient visits, yet most existing medical VQA benchmarks focus on single images or short-horizon image pairs. We introduce MI-CXR, a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Sunghwan Steve Cho , Yunseok Han , Jaeyoung Do