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Dynamic networks have been increasingly used to characterize brain connectivity that varies during resting and task states. In such characterizations, a connectivity network is typically measured at each time point for a subject over a…

Methodology · Statistics 2023-03-23 Maoyu Zhang , Biao Cai , Wenlin Dai , Dehan Kong , Hongyu Zhao , Jingfei Zhang

This paper describes an approach of using dynamic Structural Equation Modeling (SEM) analysis to estimate the connectivity networks from resting-state fMRI data measured by a multiband EPI sequence. Two structural equation models were…

Neurons and Cognition · Quantitative Biology 2017-04-03 Jiancheng Zhuang

The predictive power of neural networks often costs model interpretability. Several techniques have been developed for explaining model outputs in terms of input features; however, it is difficult to translate such interpretations into…

Machine Learning · Computer Science 2017-08-17 Benjamin J. Lengerich , Sandeep Konam , Eric P. Xing , Stephanie Rosenthal , Manuela Veloso

Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…

Networks - collections of interacting elements or nodes - abound in the natural and manmade worlds. For many networks, complex spatiotemporal dynamics stem from patterns of physical interactions unknown to us. To infer these interactions,…

Quantitative Methods · Quantitative Biology 2015-05-13 Mark A. Kramer , Uri T. Eden , Sydney S. Cash , Eric D. Kolaczyk

The idea to estimate the statistical interdependence among (interacting) brain regions has motivated numerous researchers to investigate how the resulting connectivity patterns and networks may organize themselves under any conceivable…

Neurons and Cognition · Quantitative Biology 2021-02-03 Matteo Fraschini , Simone Maurizio La Cava , Luca Didaci , Luigi Barberini

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

A novel non-parametric estimator of the correlation between grouped measurements of a quantity is proposed in the presence of noise. This work is primarily motivated by functional brain network construction from fMRI data, where brain…

Methodology · Statistics 2023-02-16 Hanâ Lbath , Alexander Petersen , Wendy Meiring , Sophie Achard

Deformable image registration estimates voxel-wise correspondences between images through spatial transformations, and plays a key role in medical imaging. While deep learning methods have significantly reduced runtime, efficiently handling…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Tianran Li , Marius Staring , Yuchuan Qiao

Brain connectivity analysis is now at the foreground of neuroscience research. A connectivity network is characterized by a graph, where nodes represent neural elements such as neurons and brain regions, and links represent statistical…

Methodology · Statistics 2015-11-04 Yin Xia , Lexin Li

Brain decoding that classifies cognitive states using the functional fluctuations of the brain can provide insightful information for understanding the brain mechanisms of cognitive functions. Among the common procedures of decoding the…

Human-Computer Interaction · Computer Science 2024-07-12 Jianfei Zhu , Baichun Wei , Jiaru Tian , Feng Jiang , Chunzhi Yi

We propose a method that combines signals from many brain regions observed in functional Magnetic Resonance Imaging (fMRI) to predict the subject's behavior during a scanning session. Such predictions suffer from the huge number of brain…

Computer Vision and Pattern Recognition · Computer Science 2011-04-29 Vincent Michel , Alexandre Gramfort , Gaël Varoquaux , Evelyn Eger , Christine Keribin , Bertrand Thirion

Recently, there has been increased interest in fusing multimodal imaging to better understand brain organization. Specifically, accounting for knowledge of anatomical pathways connecting brain regions should lead to desirable outcomes such…

Applications · Statistics 2018-03-02 Ixavier A. Higgins , Suprateek Kundu , Ying Guo

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

Neurons and Cognition · Quantitative Biology 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

Today, the human brain can be studied as a whole. Electroencephalography, magnetoencephalography, or functional magnetic resonance imaging techniques provide functional connectivity patterns between different brain areas, and during…

Data Analysis, Statistics and Probability · Physics 2011-01-21 Mario Chavez , Miguel Valencia , Vito Latora , Jacques Martinerie

The human brain is a complex network comprised of functionally and anatomically interconnected brain regions. A growing number of studies have suggested that empirical estimates of brain networks may be useful for discovery of biomarkers of…

Neurons and Cognition · Quantitative Biology 2022-11-15 Andrew Hannum , Mario A. Lopez , Saúl A. Blanco , Richard F. Betzel

Attention Deficit Hyperactive Disorder (ADHD) is a common behavioral problem affecting children. In this work, we investigate the automatic classification of ADHD subjects using the resting state Functional Magnetic Resonance Imaging (fMRI)…

Neurons and Cognition · Quantitative Biology 2023-06-16 Soumyabrata Dey , Ravishankar Rao , Mubarak Shah

A central question in neuroscience is how self-organizing dynamic interactions in the brain emerge on their relatively static structural backbone. Due to the complexity of spatial and temporal dependencies between different brain areas,…

Neurons and Cognition · Quantitative Biology 2020-10-15 Simon Wein , Wilhelm Malloni , Ana Maria Tomé , Sebastian M. Frank , Gina-Isabelle Henze , Stefan Wüst , Mark W. Greenlee , Elmar W. Lang

Dynamic functional connectivity is an effective measure for the brain's responses to continuous stimuli. We propose an inferential method to detect the dynamic changes of brain networks based on time-varying graphical models. Whereas most…

Applications · Statistics 2020-06-23 Dingjue Ji , Junwei Lu , Yiliang Zhang , Hongyu Zhao , Siyuan Gao

Some evidence suggests that people with autism spectrum disorder exhibit patterns of brain functional dysconnectivity relative to their typically developing peers, but specific findings have yet to be replicated. To facilitate this…

Methodology · Statistics 2025-03-03 Hyoshin Kim , Sujit K. Ghosh , Emily C. Hector