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The performance of deep reinforcement learning agents is fundamentally constrained by their neural network architecture, a choice traditionally made through expensive hyperparameter searches and then fixed throughout training. This work…

Machine Learning · Computer Science 2025-10-24 Iman Rahmani , Saman Yazdannik , Morteza Tayefi , Jafar Roshanian

Molecular docking is an important tool for structure-based drug design, accelerating the efficiency of drug development. Complex and dynamic binding processes between proteins and small molecules require searching and sampling over a wide…

Chemical Physics · Physics 2024-02-23 Runqiu Shu , Bowen Liu , Zhaoping Xiong , Xiaopeng Cui , Yunting Li , Wei Cui , Man-Hong Yung , Nan Qiao

Recent advancements in deep reinforcement learning (DRL) techniques have sparked its multifaceted applications in the automation sector. Managing complex decision-making problems with DRL encourages its use in the nuclear industry for tasks…

Artificial Intelligence · Computer Science 2026-02-19 Biswajit Sadhu , Trijit Sadhu , S. Anand

Synthesizable molecular design (also known as synthesizable molecular optimization) is a fundamental problem in drug discovery, and involves designing novel molecular structures to improve their properties according to drug-relevant oracle…

Machine Learning · Computer Science 2026-05-07 Dannong Wang , Jintai Chen , Yingzhou Lu , Minjie Shen , Lulu Chen , Zhiding Liang , Tianfan Fu , Xiao-Yang Liu

With the development of experimental quantum technology, quantum control has attracted increasing attention due to the realization of controllable artificial quantum systems. However, because quantum-mechanical systems are often too…

Quantum Physics · Physics 2022-12-22 Zhikang Wang

This paper introduces the QDQN-DPER framework to enhance the efficiency of quantum reinforcement learning (QRL) in solving sequential decision tasks. The framework incorporates prioritized experience replay and asynchronous training into…

Quantum Physics · Physics 2023-04-20 Samuel Yen-Chi Chen

Parameterised actions in reinforcement learning are composed of discrete actions with continuous action-parameters. This provides a framework for solving complex domains that require combining high-level actions with flexible control. The…

Machine Learning · Computer Science 2019-05-14 Craig J. Bester , Steven D. James , George D. Konidaris

Real-world reinforcement learning tasks often involve some form of partial observability where the observations only give a partial or noisy view of the true state of the world. Such tasks typically require some form of memory, where the…

Machine Learning · Computer Science 2022-11-11 Kevin Esslinger , Robert Platt , Christopher Amato

Deep Q-Network (DQN) based multi-agent systems (MAS) for reinforcement learning (RL) use various schemes where in the agents have to learn and communicate. The learning is however specific to each agent and communication may be…

Machine Learning · Computer Science 2020-08-11 Abdul Mueed Hafiz , Ghulam Mohiuddin Bhat

We present a novel algorithm to train a deep Q-learning agent using natural-gradient techniques. We compare the original deep Q-network (DQN) algorithm to its natural-gradient counterpart, which we refer to as NGDQN, on a collection of…

Machine Learning · Computer Science 2018-11-15 Ethan Knight , Osher Lerner

One of the major challenges in Deep Reinforcement Learning for control is the need for extensive training to learn the policy. Motivated by this, we present the design of the Control-Tutored Deep Q-Networks (CT-DQN) algorithm, a Deep…

Machine Learning · Computer Science 2022-12-05 Francesco De Lellis , Marco Coraggio , Giovanni Russo , Mirco Musolesi , Mario di Bernardo

Recently, multiagent deep reinforcement learning (DRL) has received increasingly wide attention. Existing multiagent DRL algorithms are inefficient when facing with the non-stationarity due to agents update their policies simultaneously in…

Multiagent Systems · Computer Science 2018-04-17 Yan Zheng , Jianye Hao , Zongzhang Zhang

Adaptive Operator Selection (AOS) is an approach that controls discrete parameters of an Evolutionary Algorithm (EA) during the run. In this paper, we propose an AOS method based on Double Deep Q-Learning (DDQN), a Deep Reinforcement…

Neural and Evolutionary Computing · Computer Science 2019-05-21 Mudita Sharma , Alexandros Komninos , Manuel Lopez Ibanez , Dimitar Kazakov

With the rapid increase in demand for mobile data, mobile network operators are trying to expand wireless network capacity by deploying wireless local area network (LAN) hotspots on to which they can offload their mobile traffic. However,…

Networking and Internet Architecture · Computer Science 2018-02-07 Cheng Zhang , Zhi Liu , Bo Gu , Kyoko Yamori , Yoshiaki Tanaka

This paper focuses on the impact of leveraging autonomous offensive approaches in Deep Reinforcement Learning (DRL) to train more robust agents by exploring the impact of applying adversarial learning to DRL for autonomous security in…

Cryptography and Security · Computer Science 2023-08-15 Luke Borchjes , Clement Nyirenda , Louise Leenen

In this paper, we propose a federated deep reinforcement learning framework to solve a multi-objective optimization problem, where we consider minimizing the expected long-term task completion delay and energy consumption of IoT devices.…

Networking and Internet Architecture · Computer Science 2021-04-26 Sheyda Zarandi , Hina Tabassum

In distributional reinforcement learning (RL), the estimated distribution of value function models both the parametric and intrinsic uncertainties. We propose a novel and efficient exploration method for deep RL that has two components. The…

Machine Learning · Computer Science 2019-05-16 Borislav Mavrin , Shangtong Zhang , Hengshuai Yao , Linglong Kong , Kaiwen Wu , Yaoliang Yu

In this paper, an operating system scheduling algorithm based on Double DQN (Double Deep Q network) is proposed, and its performance under different task types and system loads is verified by experiments. Compared with the traditional…

Machine Learning · Computer Science 2025-04-01 Xiaoxuan Sun , Yifei Duan , Yingnan Deng , Fan Guo , Guohui Cai , Yuting Peng

The aim of the inverse chemical design is to develop new molecules with given optimized molecular properties or objectives. Recently, generative deep learning (DL) networks are considered as the state-of-the-art in inverse chemical design…

Machine Learning · Computer Science 2019-10-10 Haoran Wei , Mariefel Olarte , Garrett B. Goh

Recent research has shown that although Reinforcement Learning (RL) can benefit from expert demonstration, it usually takes considerable efforts to obtain enough demonstration. The efforts prevent training decent RL agents with expert…

Machine Learning · Computer Science 2021-07-09 Si-An Chen , Voot Tangkaratt , Hsuan-Tien Lin , Masashi Sugiyama