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Background. Pre-operative risk assessments used in clinical practice are limited in their ability to identify risk for post-operative mortality. We hypothesize that electrocardiograms contain hidden risk markers that can help prognosticate…
We augment linear Support Vector Machine (SVM) classifiers by adding three important features: (i) we introduce a regularization constraint to induce a sparse classifier; (ii) we devise a method that partitions the positive class into…
Identifying the seizure onset zone (SOZ) in patients with focal epilepsy is essential for surgical treatment and remains challenging due to its dependence on visual judgment by clinical experts. The development of machine learning can…
Predicting discharge medications right after a patient being admitted is an important clinical decision, which provides physicians with guidance on what type of medication regimen to plan for and what possible changes on initial medication…
Post-translational modifications (PTMs) have key roles in extending the functional diversity of proteins and as a result, regulating diverse cellular processes in prokaryotic and eukaryotic organisms. Phosphorylation modification is a vital…
The prediction of epileptic seizure has always been extremely challenging in medical domain. However, as the development of computer technology, the application of machine learning introduced new ideas for seizure forecasting. Applying…
Permeability is a central concept in the macroscopic description of flow through porous media, with applications spanning from oil recovery to hydrology. Traditional methods for determining the permeability tensor involving flow simulations…
Prognostic covariate adjustment (PROCOVA) is a two-sample two-stage estimation method used in randomized controlled trials. In the first stage, a prognostic score, defined as the conditional expectation of an outcome given covariates under…
Background: Pleural Mesothelioma (PM) is an unusual, belligerent tumor that rapidly develops into cancer in the pleura of the lungs. Pleural Mesothelioma is a common type of Mesothelioma that accounts for about 75% of all Mesothelioma…
Chronic pain (CP) and opioid use disorder (OUD) are common and interrelated chronic medical conditions. Currently, there is a paucity of evidence-based integrated treatments for CP and OUD among individuals receiving medication for opioid…
Recent developments in medical imaging with Deep Learning presents evidence of automated diagnosis and prognosis. It can also be a complement to currently available diagnosis methods. Deep Learning can be leveraged for diagnosis, severity…
The COVID-19 pandemic has left a lasting impact on individuals, with many experiencing persistent symptoms, including inflammation, in the post-acute phase of the disease. Detecting and monitoring these inflammatory biomarkers is critical…
We develop a novel algorithm to predict the occurrence of major abdominal surgery within 5 years following Crohn's disease diagnosis using a panel of 29 baseline covariates from the Swedish population registers. We model pseudo-observations…
Artificial intelligence and deep learning are increasingly applied in the clinical domain, particularly for early and accurate disease detection using medical imaging and sound. Due to limited trained personnel, there is a growing demand…
Pneumonia has been one of the fatal diseases and has the potential to result in severe consequences within a short period of time, due to the flow of fluid in lungs, which leads to drowning. If not acted upon by drugs at the right time,…
Prolonged length of stay (pLoS) is a significant factor associated with the risk of adverse in-hospital events. We develop and explain a predictive model for pLos using admission-level patient and hospital administrative data. The approach…
The infection of respiratory coronavirus disease 2019 (COVID-19) starts with the upper respiratory tract and as the virus grows, the infection can progress to lungs and develop pneumonia. The conventional way of COVID-19 diagnosis is…
Purpose: Subarachnoid haemorrhage is a potentially fatal consequence of intracranial aneurysm rupture, however, it is difficult to predict if aneurysms will rupture. Prophylactic treatment of an intracranial aneurysm also involves risk,…
Post-traumatic stress disorder (PTSD) is a significant mental health challenge that affects individuals exposed to traumatic events. Early detection and effective intervention for PTSD are crucial, as it can lead to long-term psychological…
Polyps are well-known cancer precursors identified by colonoscopy. However, variability in their size, location, and surface largely affect identification, localisation, and characterisation. Moreover, colonoscopic surveillance and removal…