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Accurate identification of protein-nucleotide binding sites is fundamental to deciphering molecular mechanisms and accelerating drug discovery. However, current computational methods often struggle with suboptimal performance due to…

Machine Learning · Computer Science 2026-03-17 Yiming Gao , Liuyi Xu , Pengshan Cui , Yining Qian , An-Yang Lu , Xianpeng Wang

In this article we provide a comprehensive review of the different evolutionary algorithm techniques used to address multimodal optimization problems, classifying them according to the nature of their approach. On the one hand there are…

Neural and Evolutionary Computing · Computer Science 2015-08-24 Noe Casas

Kernel methods are an important class of techniques in machine learning. To be effective, good feature maps are crucial for mapping non-linearly separable input data into a higher dimensional (feature) space, thus allowing the data to be…

Quantum Physics · Physics 2024-07-16 Rowan Pellow-Jarman , Anban Pillay , Ilya Sinayskiy , Francesco Petruccione

The user-level brokers in grids consider individual application QoS requirements and minimize their cost without considering demands from other users. This results in contention for resources and sub-optimal schedules. Meta-scheduling in…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-03-10 Saurabh Garg , Pramod Konugurthi , Rajkumar Buyya

Optimal Mixing (OM) is a variation operator that integrates local search with genetic recombination. EAs with OM are capable of state-of-the-art optimization in discrete spaces, offering significant advantages over classic…

Neural and Evolutionary Computing · Computer Science 2025-06-19 Anton Bouter , Dirk Thierens , Peter A. N. Bosman

A genetic algorithm is suitable for exploring large search spaces as it finds an approximate solution. Because of this advantage, genetic algorithm is effective in exploring vast and unknown space such as molecular search space. Though the…

Neural and Evolutionary Computing · Computer Science 2021-12-24 Yurim Lee , Gydam Choi , Minsung Yoon , Cheongwon Kim

Genetic algorithms are modeled after the biological evolutionary processes that use natural selection to select the best species to survive. They are heuristics based and low cost to compute. Genetic algorithms use selection, crossover, and…

Neural and Evolutionary Computing · Computer Science 2020-05-28 Mee Seong Im , Venkat R. Dasari

This research introduces a novel methodology for optimizing Bayesian Neural Networks (BNNs) by synergistically integrating them with traditional machine learning algorithms such as Random Forests (RF), Gradient Boosting (GB), and Support…

Machine Learning · Computer Science 2023-10-10 Peiwen Tan

This paper provides an in-depth empirical analysis of several evolutionary algorithms on the one-dimensional spin glass model with power-law interactions. The considered spin glass model provides a mechanism for tuning the effective range…

Disordered Systems and Neural Networks · Physics 2009-07-29 Martin Pelikan , Helmut G. Katzgraber

Quantum algorithms are emerging tools in the design of functional materials due to their powerful solution space search capability. How to balance the high price of quantum computing resources and the growing computing needs has become an…

Quantum Physics · Physics 2024-05-13 Zhihao Xu , Wenjie Shang , Seongmin Kim , Alexandria Bobbitt , Eungkyu Lee , Tengfei Luo

The Simple Genetic Algorithm, the Univariate Marginal Distribution Algorithm, the Extended Compact Genetic Algorithm, and the Hierarchical Bayesian Optimization Algorithm are all well known Evolutionary Algorithms. In this report we present…

Neural and Evolutionary Computing · Computer Science 2015-06-29 José C. Pereira , Fernando G. Lobo

We investigate a family of $(\mu+\lambda)$ Genetic Algorithms (GAs) which creates offspring either from mutation or by recombining two randomly chosen parents. By scaling the crossover probability, we can thus interpolate from a fully…

Neural and Evolutionary Computing · Computer Science 2021-02-16 Furong Ye , Hao Wang , Carola Doerr , Thomas Bäck

The potential benefit of migrating software design from Structured to Object Oriented Paradigm is manifolded including modularity, manageability and extendability. This design migration should be automated as it will reduce the time…

Software Engineering · Computer Science 2018-01-04 Md. Selim , Saeed Siddik , Alim Ul Gias , M. Abdullah-Al-Wadud , Shah Mostafa Khaled

Evolutionary algorithms rely very heavily on randomized behavior. Execution speed, therefore, depends strongly on how we implement randomness, such as our choice of pseudorandom number generator, or the algorithms used to map pseudorandom…

Neural and Evolutionary Computing · Computer Science 2024-12-04 Vincent A. Cicirello

The 0-1 knapsack problem is a well-known combinatorial optimisation problem. Approximation algorithms have been designed for solving it and they return provably good solutions within polynomial time. On the other hand, genetic algorithms…

Neural and Evolutionary Computing · Computer Science 2014-04-04 Jun He , Feidun He , Hongbin Dong

Inspired by the effectiveness of genetic algorithms and the importance of synthesizability in molecular design, we present SynGA, a simple genetic algorithm that operates directly over synthesis routes. Our method features custom crossover…

Machine Learning · Computer Science 2026-03-03 Alston Lo , Connor W. Coley , Wojciech Matusik

We propose a gate-based Quantum Genetic Algorithm (QGA) for real-valued global optimization. In this model, individuals are represented by quantum circuits whose measurement outcomes are decoded into real-valued vectors through binary…

Quantum Physics · Physics 2025-11-10 Leandro C. Souza , Laurent E. Dardenne , Renato Portugal

In this paper the approach to solving several combinatorial optimization problems using the local search and the genetic algorithm techniques is proposed. Initially this approach was developed in purpose to overcome some difficulties…

Neural and Evolutionary Computing · Computer Science 2010-04-30 Anton Bondarenko

The paper presents a method for failure free genetic algorithm optimization of a system controller. Genetic algorithms present a powerful tool that facilitates producing near-optimal system controllers. Applied to such methods of…

Neural and Evolutionary Computing · Computer Science 2007-05-23 E. S. Sazonov , D. Del Gobbo , P. Klinkhachorn , R. L. Klein

Back-propagation algorithm is one of the most widely used and popular techniques to optimize the feed forward neural network training. Nature inspired meta-heuristic algorithms also provide derivative-free solution to optimize complex…

Neural and Evolutionary Computing · Computer Science 2012-09-13 Sudarshan Nandy , Partha Pratim Sarkar , Achintya Das
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