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Quantum computing for the biological sciences is an area of rapidly growing interest, but specific industrial applications remain elusive. Quantum Markov chain Monte Carlo has been proposed as a method for accelerating a broad class of…

We investigate the use of quantum computing algorithms on real quantum hardware to tackle the computationally intensive task of feature selection for light-weight medical image datasets. Feature selection is often formulated as a k of n…

Quantum Physics · Physics 2025-02-27 Merlin A. Nau , Luca A. Nutricati , Bruno Camino , Paul A. Warburton , Andreas K. Maier

This study investigates quantum computing's role in B-cell epitope prediction using Quantum Support Vector Machine (QSVM) and Variational Quantum Classifier (VQC). It highlights the potential of quantum machine learning in bioinformatics,…

Quantum Physics · Physics 2025-04-17 Chi-Chuan Hwang , Yi-Ang Hong

Quantum computing technology is advancing rapidly. Yet, even accounting for these trends, a quantum leap would be needed for quantum computers to meaningfully impact deep learning over the coming decade or two. We arrive at this conclusion…

Quantum Physics · Physics 2025-11-04 Hans Gundlach , Hrvoje Kukina , Jayson Lynch , Neil Thompson

Harnessing the potential computational advantage of quantum computers for machine learning tasks relies on the uploading of classical data onto quantum computers through what are commonly referred to as quantum encodings. The choice of such…

Quantum Physics · Physics 2024-12-24 Arthur J. Parzygnat , Tai-Danae Bradley , Andrew Vlasic , Anh Pham

Prime factorization is a difficult problem with classical computing, whose exponential hardness is the foundation of Rivest-Shamir-Adleman (RSA) cryptography. With programmable quantum devices, adiabatic quantum computing has been proposed…

Quantum Physics · Physics 2022-07-01 Jian Lin , Zhengfeng Zhang , Junping Zhang , Xiaopeng Li

Qualitative structure-activity relationship (QSAR) is important for drug discovery and offers valuable insights into the biological interactions of potential drug candidates. It has been demonstrated that QSAR can be accurately predicted by…

Quantum Physics · Physics 2025-01-24 Wei-Yin Chiang , Po-Yu Kao , Tzu-Lan Yeh , Ya-Chu Yang , Yen-Chu Lin , Alex Zhavoronkov

Quantum annealing is a promising paradigm for building practical quantum computers. Compared to other approaches, quantum annealing technology has been scaled up to a larger number of qubits. On the other hand, deep learning has been…

Quantum Physics · Physics 2021-07-07 Michele Sasdelli , Tat-Jun Chin

Kernel methods are a cornerstone of classical machine learning. The idea of using quantum computers to compute kernels has recently attracted attention. Quantum embedding kernels (QEKs) constructed by embedding data into the Hilbert space…

Identifying a biclique with the maximum number of edges bears considerable implications for numerous fields of application, such as detecting anomalies in E-commerce transactions, discerning protein-protein interactions in biology, and…

Quantum Physics · Physics 2023-09-12 Xiaofan Li , Prasenjit Mitra , Rui Zhou , Wolfgang Nejdl

Predicting the 3D structure of a macromolecule, such as a protein or an RNA molecule, is ranked top among the most difficult and attractive problems in bioinformatics and computational biology. Its importance comes from the relationship…

Biomolecules · Quantitative Biology 2016-12-14 Zhiyong Wang

Quantum computing holds great potential for advancing the limitations of machine learning algorithms to handle higher dimensions of data and reduce overall training parameters in deep learning (DL) models. This study uses a trainable…

Quantum Physics · Physics 2023-12-05 Hao-Yuan Chen , Yen-Jui Chang , Shih-Wei Liao , Ching-Ray Chang

Quantum kernel methods (QKMs) have emerged as a prominent framework for supervised quantum machine learning. Unlike variational quantum algorithms, which rely on gradient-based optimisation and may suffer from issues such as barren…

Quantum Physics · Physics 2026-04-10 John Tanner , Chon-Fai Kam , Jingbo Wang

AlphaFold 3 (AF3), the latest version of protein structure prediction software, goes beyond its predecessors by predicting protein-protein complexes. It could revolutionize drug discovery and protein engineering, marking a major step…

Biomolecules · Quantitative Biology 2024-06-07 JunJie Wee , Guo-Wei Wei

Quantum machine learning (QML) is a promising early use case for quantum computing. There has been progress in the last five years from theoretical studies and numerical simulations to proof of concepts. Use cases demonstrated on…

Quantum Physics · Physics 2024-04-30 Daniel Goldsmith , M M Hassan Mahmud

Quantum computing holds transformative potential for medical applications, yet efficiently preparing quantum states from complex medical data remains a fundamental challenge. This survey provides a comprehensive examination of current…

Quantum Physics · Physics 2025-08-08 Nikhil Kumar Rajput , Riya Bansal

The connection and eventual integration of High-Performance Computing (HPC) with Quantum Computing (QC) represents a transformative advancement in computational technology, promising significant enhancements in solving complex, previously…

Machine learning and quantum computing are being progressively explored to shed light on possible computational approaches to deal with hitherto unsolvable problems. Classical methods for machine learning are ubiquitous in pattern…

Quantum Physics · Physics 2024-07-10 Papri Saha

High-dimensional quantum systems are vital for quantum technologies and are essential in demonstrating practical quantum advantage in quantum computing, simulation and sensing. Since dimensionality grows exponentially with the number of…

Quantum Physics · Physics 2020-07-01 Nana Liu , Peter Wittek

A software product line models the variability of highly configurable systems. Complete exploration of all valid configurations (the configuration space) is infeasible as it grows exponentially with the number of features in the worst case.…

Quantum Physics · Physics 2023-07-28 Joshua Ammermann , Tim Bittner , Domenik Eichhorn , Ina Schaefer , Christoph Seidl
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