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In digital pathology, cell detection and classification are often prerequisites to quantify cell abundance and explore tissue spatial heterogeneity. However, these tasks are particularly challenging for multiplex immunohistochemistry (mIHC)…
Knowing a biomolecule's structure is inherently linked to and a prerequisite for any detailed understanding of its function. Significant effort has gone into developing technologies for structural characterization. These technologies do not…
Survival analysis, as a challenging task, requires integrating Whole Slide Images (WSIs) and genomic data for comprehensive decision-making. There are two main challenges in this task: significant heterogeneity and complex inter- and…
Composed Image Retrieval (CIR) retrieves target images using a multi-modal query that combines a reference image with text describing desired modifications. The primary challenge is effectively fusing this visual and textual information.…
Dataset distillation reduces the storage and computational consumption of training a network by generating a small surrogate dataset that encapsulates rich information of the original large-scale one. However, previous distillation methods…
Coupling a multi-capillary column (MCC) with an ion mobility (IM) spectrometer (IMS) opened a multitude of new application areas for gas analysis, especially in a medical context, as volatile organic compounds (VOCs) in exhaled breath can…
Definition bias is a negative phenomenon that can mislead models. Definition bias in information extraction appears not only across datasets from different domains but also within datasets sharing the same domain. We identify two types of…
Incomplete propagation data significantly hinders robust fake news detection. Recent approaches leverage large language models to simulate missing user interactions via role-playing, thereby enriching propagation with synthetic signals.…
This philosophical paper proposes a modified version of the scientific method, in which large databases are used instead of experimental observations as the necessary empirical ingredient. This change in the source of the empirical data…
Multiresolution analysis and matrix factorization are foundational tools in computer vision. In this work, we study the interface between these two distinct topics and obtain techniques to uncover hierarchical block structure in symmetric…
Delineating anatomical regions is a key task in medical image analysis. Manual segmentation achieves high accuracy but is labor-intensive and prone to variability, thus prompting the development of automated approaches. Recently, a breadth…
Multi-view representation learning aims to capture comprehensive information from multiple views of a shared context. Recent works intuitively apply contrastive learning to different views in a pairwise manner, which is still scalable:…
The development of molecular signatures for the prediction of time-to-event outcomes is a methodologically challenging task in bioinformatics and biostatistics. Although there are numerous approaches for the derivation of marker…
In this paper we introduce the SCoRe (Submodular Combinatorial Representation Learning) framework, a novel approach in representation learning that addresses inter-class bias and intra-class variance. SCoRe provides a new combinatorial…
The information bottleneck principle provides an information-theoretic method for representation learning, by training an encoder to retain all information which is relevant for predicting the label while minimizing the amount of other,…
Modern life largely transmits genetic information from mother to daughter through the duplication of single physically intact molecules that encode information. However, copying an extended molecule requires complex copying machinery and…
The efficacy of mathematical models heavily depends on the quality of the training data, yet collecting sufficient data is often expensive and challenging. Many modeling applications require inferring parameters only as a means to predict…
High-performance catalysts are crucial for sustainable energy conversion and human health. However, the discovery of catalysts faces challenges due to the absence of efficient approaches to navigating vast and high-dimensional structure and…
Estimating an individual's potential response to interventions from observational data is of high practical relevance for many domains, such as healthcare, public policy or economics. In this setting, it is often the case that combinations…
In order to define the process of restrosynthesis of a new organic molecule, it is often necessary to be able to draw inspiration from that of a molecule similar to the target one of which we know such a process. To compute such a…