English
Related papers

Related papers: Instruction-tuning Aligns LLMs to the Human Brain

200 papers

Large Language Models (LLMs) have revolutionized the field of natural language processing, but they fall short in comprehending biological sequences such as proteins. To address this challenge, we propose InstructProtein, an innovative LLM…

Biomolecules · Quantitative Biology 2023-10-06 Zeyuan Wang , Qiang Zhang , Keyan Ding , Ming Qin , Xiang Zhuang , Xiaotong Li , Huajun Chen

People acquire concepts through rich physical and social experiences and use them to understand and navigate the world. In contrast, large language models (LLMs), trained solely through next-token prediction on text, exhibit strikingly…

Computation and Language · Computer Science 2025-11-11 Ningyu Xu , Qi Zhang , Chao Du , Qiang Luo , Xipeng Qiu , Xuanjing Huang , Menghan Zhang

Reasoning is a cognitive process of using evidence to reach a sound conclusion. The reasoning capability is essential for large language models (LLMs) to serve as the brain of the artificial general intelligence agent. Recent studies reveal…

Computation and Language · Computer Science 2023-09-06 Peiyi Wang , Lei Li , Liang Chen , Feifan Song , Binghuai Lin , Yunbo Cao , Tianyu Liu , Zhifang Sui

When we read, we make predictions about upcoming words; these predictions influence our reading behavior. The success of large language models (LLMs), which, like humans, make predictions about upcoming words, has motivated their use as…

Computation and Language · Computer Science 2026-05-27 Byung-Doh Oh , Tal Linzen

Large language models (LLMs) increasingly operate in environments where they encounter social information such as other agents' answers, tool outputs, or human recommendations. In humans, such inputs influence judgments in ways that depend…

Artificial Intelligence · Computer Science 2026-02-17 Anooshka Bajaj , Zoran Tiganj

Fine-tuning large language models (LLMs) on multi-task instruction-following data has been proven to be a powerful learning paradigm for improving their zero-shot capabilities on new tasks. Recent works about high-quality…

Computation and Language · Computer Science 2024-06-17 Wei Han , Hui Chen , Soujanya Poria

While Large Language Models (LLMs) have demonstrated exceptional multitasking abilities, fine-tuning these models on downstream, domain-specific datasets is often necessary to yield superior performance on test sets compared to their…

Computation and Language · Computer Science 2024-03-15 Haoran Yang , Yumeng Zhang , Jiaqi Xu , Hongyuan Lu , Pheng Ann Heng , Wai Lam

While a large body of literature suggests that large language models (LLMs) acquire rich linguistic representations, little is known about whether they adapt to linguistic biases in a human-like way. The present study probes this question…

Computation and Language · Computer Science 2023-05-29 Suet-Ying Lam , Qingcheng Zeng , Kexun Zhang , Chenyu You , Rob Voigt

Large language models (LLMs) have shown tremendous success in following user instructions and generating helpful responses. Nevertheless, their robustness is still far from optimal, as they may generate significantly inconsistent responses…

Computation and Language · Computer Science 2024-03-25 Yukun Zhao , Lingyong Yan , Weiwei Sun , Guoliang Xing , Shuaiqiang Wang , Chong Meng , Zhicong Cheng , Zhaochun Ren , Dawei Yin

In order for large language model (LLM)-based assistants to effectively adapt to evolving information needs, it must be possible to update their factual knowledge through continued training on new data. The standard recipe for doing so…

Computation and Language · Computer Science 2024-05-28 Zhengbao Jiang , Zhiqing Sun , Weijia Shi , Pedro Rodriguez , Chunting Zhou , Graham Neubig , Xi Victoria Lin , Wen-tau Yih , Srinivasan Iyer

Big models, exemplified by Large Language Models (LLMs), are models typically pre-trained on massive data and comprised of enormous parameters, which not only obtain significantly improved performance across diverse tasks but also present…

Artificial Intelligence · Computer Science 2023-09-06 Jing Yao , Xiaoyuan Yi , Xiting Wang , Jindong Wang , Xing Xie

To acquire instruction-following capabilities, large language models (LLMs) undergo instruction tuning, where they are trained on instruction-response pairs using next-token prediction (NTP). Efforts to improve instruction tuning often…

Computation and Language · Computer Science 2026-04-21 Yuxin Xiao , Shujian Zhang , Wenxuan Zhou , Marzyeh Ghassemi , Sanqiang Zhao

Pre-trained large language models (LLMs) can be tailored to adhere to human instructions through instruction tuning. However, due to shifts in the distribution of test-time data, they may not always execute instructions accurately,…

Computation and Language · Computer Science 2024-09-04 Hai Ye , Hwee Tou Ng

Recent work in large language modeling (LLMs) has used fine-tuning to align outputs with the preferences of a prototypical user. This work assumes that human preferences are static and homogeneous across individuals, so that aligning to a a…

A central goal of cognitive modeling is to develop models that not only predict human behavior but also provide insight into the underlying cognitive mechanisms. While neural network models trained on large-scale behavioral data often…

Artificial Intelligence · Computer Science 2026-02-03 Jian-Qiao Zhu , Hanbo Xie , Dilip Arumugam , Robert C. Wilson , Thomas L. Griffiths

Generative AI, especially via Large Language Models (LLMs), has transformed content creation across text, images, and music, showcasing capabilities in following instructions through prompting, largely facilitated by instruction tuning.…

Artificial Intelligence · Computer Science 2024-07-29 Amit Sheth , Vishal Pallagani , Kaushik Roy

Conversational human-likeness plays a central role in human-AI interaction, yet it has remained difficult to define, measure, and optimize. As a result, improvements in human-like behavior are largely driven by scale or broad supervised…

Artificial Intelligence · Computer Science 2026-01-08 Masum Hasan , Junjie Zhao , Ehsan Hoque

Large language models (LLMs) exhibit advanced reasoning skills, enabling robots to comprehend natural language instructions and strategically plan high-level actions through proper grounding. However, LLM hallucination may result in robots…

Artificial Intelligence · Computer Science 2025-02-12 Kaiqu Liang , Zixu Zhang , Jaime Fernández Fisac

Large language models (LLMs) are increasingly used in decision-making contexts, but when they present answers without signaling low confidence, users may unknowingly act on erroneous outputs. Prior work shows that LLMs maintain internal…

Computation and Language · Computer Science 2025-10-23 Mark Steyvers , Catarina Belem , Padhraic Smyth

Instruction-tuned Large Language Models (LLMs) have achieved remarkable performance across various benchmark tasks. While providing instructions to LLMs for guiding their generations is user-friendly, assessing their instruction-following…

Computation and Language · Computer Science 2024-06-25 Rem Hida , Junki Ohmura , Toshiyuki Sekiya