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A major limitation in applying deep learning to artificial intelligence (AI) systems is the scarcity of high-quality curated datasets. We investigate strong augmentation based self-supervised learning (SSL) techniques to address this…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 John D. Miller , Vignesh A. Arasu , Albert X. Pu , Laurie R. Margolies , Weiva Sieh , Li Shen

Data-driven methods have shown tremendous progress in medical image analysis. In this context, deep learning-based supervised methods are widely popular. However, they require a large amount of training data and face issues in…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Ziang Xu , Jens Rittscher , Sharib Ali

A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to…

Computer Vision and Pattern Recognition · Computer Science 2020-11-02 Krishna Chaitanya , Ertunc Erdil , Neerav Karani , Ender Konukoglu

Deep learning models for radiology interpretation increasingly rely on multi-institutional data, yet privacy regulations and distribution shift across hospitals limit central data pooling. Federated learning (FL) allows hospitals to…

Machine Learning · Computer Science 2026-01-13 Anay Sinhal , Arpana Sinhal , Amit Sinhal

3D medical image segmentation methods have been successful, but their dependence on large amounts of voxel-level annotated data is a disadvantage that needs to be addressed given the high cost to obtain such annotation. Semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Yuyuan Liu , Yu Tian , Chong Wang , Yuanhong Chen , Fengbei Liu , Vasileios Belagiannis , Gustavo Carneiro

Supervised learning has proved effective for medical image analysis. However, it can utilize only the small labeled portion of data; it fails to leverage the large amounts of unlabeled data that is often available in medical image datasets.…

Computer Vision and Pattern Recognition · Computer Science 2020-04-28 Gaurav Fotedar , Nima Tajbakhsh , Shilpa Ananth , Xiaowei Ding

Collecting large-scale medical datasets with fully annotated samples for training of deep networks is prohibitively expensive, especially for 3D volume data. Recent breakthroughs in self-supervised learning (SSL) offer the ability to…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Duy M. H. Nguyen , Hoang Nguyen , Mai T. N. Truong , Tri Cao , Binh T. Nguyen , Nhat Ho , Paul Swoboda , Shadi Albarqouni , Pengtao Xie , Daniel Sonntag

Spatial transcriptomics (ST) provides spatially resolved measurements of gene expression, enabling characterization of the molecular landscape of human tissue beyond histological assessment as well as localized readouts that can be aligned…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Konstantin Hemker , Andrew H. Song , Cristina Almagro-Pérez , Guillaume Jaume , Sophia J. Wagner , Anurag Vaidya , Nikola Simidjievski , Mateja Jamnik , Faisal Mahmood

Limited labeled data hinder the application of deep learning in medical domain. In clinical practice, there are sufficient unlabeled data that are not effectively used, and semi-supervised learning (SSL) is a promising way for leveraging…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Along He , Tao Li , Yanlin Wu , Ke Zou , Huazhu Fu

In this paper, we propose a novel, effective and simpler end-to-end image clustering auto-encoder algorithm: ICAE. The algorithm uses PEDCC (Predefined Evenly-Distributed Class Centroids) as the clustering centers, which ensures the…

Computer Vision and Pattern Recognition · Computer Science 2021-08-24 Qiuyu Zhu , Zhengyong Wang

This article presents a general Bayesian learning framework for multi-modal groupwise image registration. The method builds on probabilistic modelling of the image generative process, where the underlying common anatomy and geometric…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Xinzhe Luo , Xin Wang , Linda Shapiro , Chun Yuan , Jianfeng Feng , Xiahai Zhuang

Challenges such as the lack of high-quality annotations, long-tailed data distributions, and inconsistent staining styles pose significant obstacles to training neural networks to detect abnormal cells in cytopathology robustly. This paper…

Computer Vision and Pattern Recognition · Computer Science 2025-06-27 Qiuyi Qi , Xin Li , Ming Kong , Zikang Xu , Bingdi Chen , Qiang Zhu , S Kevin Zhou

Semi-supervised learning (SSL) is a popular solution to alleviate the high annotation cost in medical image classification. As a main branch of SSL, consistency regularization engages in imposing consensus between the predictions of a…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Zhang Qixiang , Yang Yuxiang , Zu Chen , Zhang Jianjia , Wu Xi , Zhou Jiliu , Wang Yan

Medical image segmentation is a pivotal step in diagnostic and therapeutic processes, relying on high-quality annotated data that is often challenging and costly to obtain. Semi-supervised learning offers a promising approach to enhance…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Yuxuan Cheng , Chenxi Shao , Jie Ma , Yunfei Xie , Guoliang Li

Medical image segmentation has significantly benefitted thanks to deep learning architectures. Furthermore, semi-supervised learning (SSL) has recently been a growing trend for improving a model's overall performance by leveraging abundant…

Image and Video Processing · Electrical Eng. & Systems 2021-10-05 S. M. Kamrul Hasan , Cristian A. Linte

Developing artificial intelligence (AI) and machine learning (ML) models for medical imaging typically involves extensive training and testing on large datasets, consuming significant computational time, energy, and resources. There is a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Raj Hansini Khoiwal , Alan B. McMillan

We present a self-supervised algorithm for several classification tasks within hematoxylin and eosin (H&E) stained images of breast cancer. Our method is robust to stain variations inherent to the histology images acquisition process, which…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Alexandre Tiard , Alex Wong , David Joon Ho , Yangchao Wu , Eliram Nof , Alvin C. Goh , Stefano Soatto , Saad Nadeem

The existing barely-supervised medical image segmentation (BSS) methods, adopting a registration-segmentation paradigm, aim to learn from data with very few annotations to mitigate the extreme label scarcity problem. However, this paradigm…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Junming Su , Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane

Although the preservation of shape continuity and physiological anatomy is a natural assumption in the segmentation of medical images, it is often neglected by deep learning methods that mostly aim for the statistical modeling of input data…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 Yousef Yeganeh , Azade Farshad , Goktug Guevercin , Amr Abu-zer , Rui Xiao , Yongjian Tang , Ehsan Adeli , Nassir Navab

Deep convolutional neural networks have achieved remarkable progress on a variety of medical image computing tasks. A common problem when applying supervised deep learning methods to medical images is the lack of labeled data, which is very…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Xiaomeng Li , Lequan Yu , Hao Chen , Chi-Wing Fu , Lei Xing , Pheng-Ann Heng
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