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Quantitative susceptibility mapping (QSM) is a valuable magnetic resonance imaging (MRI) contrast mechanism that has demonstrated broad clinical applications. However, the image reconstruction of QSM is challenging due to its ill-posed…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Yang Gao , Xuanyu Zhu , Bradford A. Moffat , Rebecca Glarin , Alan H. Wilman , G. Bruce Pike , Stuart Crozier , Feng Liu , Hongfu Sun

Despite the promise of Convolutional neural network (CNN) based classification models for histopathological images, it is infeasible to quantify its uncertainties. Moreover, CNNs may suffer from overfitting when the data is biased. We show…

Computer Vision and Pattern Recognition · Computer Science 2021-11-09 Ponkrshnan Thiagarajan , Pushkar Khairnar , Susanta Ghosh

A major remaining challenge for magnetic resonance-based attenuation correction methods (MRAC) is their susceptibility to sources of MRI artifacts (e.g. implants, motion) and uncertainties due to the limitations of MRI contrast (e.g.…

Deep learning-based surrogate models have demonstrated remarkable advantages over classical solvers in terms of speed, often achieving speedups of 10 to 1000 times over traditional partial differential equation (PDE) solvers. However, a…

Machine Learning · Computer Science 2024-02-14 Tailin Wu , Willie Neiswanger , Hongtao Zheng , Stefano Ermon , Jure Leskovec

The search for relics from the inflation era in the form of B-mode polarization of the CMB is a major challenge in cosmology. The main obstacle appears to come from the complexity of Galactic foregrounds that need to be removed.…

The analysis of astronomical interferometric data is often performed on the images obtained after deconvolution of the interferometer's point spread function (PSF). This strategy can be understood (especially for cases of sparse arrays) as…

Instrumentation and Methods for Astrophysics · Physics 2015-06-18 I. Marti-Vidal , W. H. T. Vlemmings , S. Muller , S. Casey

In a recent article series, the authors have promoted convex optimization algorithms for radio-interferometric imaging in the framework of compressed sensing, which leverages sparsity regularization priors for the associated inverse problem…

Instrumentation and Methods for Astrophysics · Physics 2014-04-01 Rafael E. Carrillo , Jason D. McEwen , Yves Wiaux

In complex physical process characterization, such as the measurement of the regression rate for solid hybrid rocket fuels, where both the observation data and the model used have uncertainties originating from multiple sources, combining…

Machine Learning · Computer Science 2023-03-21 Georgios Georgalis , Kolos Retfalvi , Paul E. DesJardin , Abani Patra

On top of machine learning models, uncertainty quantification (UQ) functions as an essential layer of safety assurance that could lead to more principled decision making by enabling sound risk assessment and management. The safety and…

Machine Learning · Computer Science 2024-03-28 Venkat Nemani , Luca Biggio , Xun Huan , Zhen Hu , Olga Fink , Anh Tran , Yan Wang , Xiaoge Zhang , Chao Hu

We establish a unified statistical framework that underscores the crucial role statistical inference plays in Quantum Amplitude Estimation (QAE), a task essential to fields ranging from chemistry to finance and machine learning. We use this…

Quantum Physics · Physics 2026-01-14 Qilin Li , Atharva Vidwans , Yazhen Wang , Micheline B. Soley

We present an efficient approach to quantify the uncertainties associated with the numerical simulations of the laser-based powder bed fusion of metals processes. Our study focuses on a thermomechanical model of an Inconel 625 cantilever…

Computational Engineering, Finance, and Science · Computer Science 2024-03-21 Mihaela Chiappetta , Chiara Piazzola , Lorenzo Tamellini , Alessandro Reali , Ferdinando Auricchio , Massimo Carraturo

This paper is concerned with a lesser-studied problem in the context of model-based, uncertainty quantification (UQ), that of optimization/design/control under uncertainty. The solution of such problems is hindered not only by the usual…

Computation · Statistics 2016-02-17 Phaedon-Stelios Koutsourelakis

Image-based computational fluid dynamics (CFD) modeling enables derivation of hemodynamic information, which has become a paradigm in cardiovascular research and healthcare. Nonetheless, the predictive accuracy largely depends on precisely…

Fluid Dynamics · Physics 2021-07-20 Han Gao , Xueyu Zhu , Jian-Xun Wang

We develop an ultrawideband (UWB) inverse scattering technique for reconstructing continuous random media based on Bayesian compressive sensing. In addition to providing maximum a posteriori estimates of the unknown weights, Bayesian…

Data Analysis, Statistics and Probability · Physics 2014-11-27 A. E. Fouda , F. L. Teixeira

Uncertainty quantification (UQ) in deep learning regression is of wide interest, as it supports critical applications including sequential decision making and risk-sensitive tasks. In heteroskedastic regression, where the uncertainty of the…

Machine Learning · Computer Science 2026-03-03 Mikkel Jordahn , Jonas Vestergaard Jensen , James Harrison , Michael Riis Andersen , Mikkel N. Schmidt

Breast cancer remains the leading cause of cancer-related mortality among women worldwide, necessitating the meticulous examination of mammograms by radiologists to characterize abnormal lesions. This manual process demands high accuracy…

Image and Video Processing · Electrical Eng. & Systems 2024-11-25 Laia Domingo , Mahdi Chehimi

Reconstructing high-quality images from substantially undersampled k-space data for accelerated MRI presents a challenging ill-posed inverse problem. While supervised deep learning has revolutionized this field, it relies heavily on large…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Xinzhe Luo , Yingzhen Li , Chen Qin

Ultrasound imaging is one of the most widely used diagnostic modalities, offering real-time, radiation-free assessment across diverse clinical domains. However, interpretation of ultrasound images remains challenging due to high noise…

Image and Video Processing · Electrical Eng. & Systems 2025-11-10 Youssef Megahed , Robin Ducharme , Aylin Erman , Mark Walker , Steven Hawken , Adrian D. C. Chan

We present a simple and effective approach for posterior uncertainty quantification in deep operator networks (DeepONets); an emerging paradigm for supervised learning in function spaces. We adopt a frequentist approach based on randomized…

Machine Learning · Computer Science 2022-08-17 Yibo Yang , Georgios Kissas , Paris Perdikaris

Quantitative inversion algorithms allow for the reconstruction of electrical properties (such as permittivity, and conductivity) for every point in a scene. However, they are challenging to use on measured datasets due to the need to know…

Signal Processing · Electrical Eng. & Systems 2025-05-15 Zacharie Idriss , Raghu Raj
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