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The joint analysis of biomedical data in Alzheimer's Disease (AD) is important for better clinical diagnosis and to understand the relationship between biomarkers. However, jointly accounting for heterogeneous measures poses important…

Methodology · Statistics 2018-08-14 Luigi Antelmi , Nicholas Ayache , Philippe Robert , Marco Lorenzi

We consider a parametric modelling approach for survival data where covariates are allowed to enter the model through multiple distributional parameters, i.e., scale and shape. This is in contrast with the standard convention of having a…

Methodology · Statistics 2021-11-17 Fatima-Zahra Jaouimaa , Il Do Ha , Kevin Burke

This work addresses the challenge of making generative models suitable for resource-constrained environments like mobile wireless communication systems. We propose a generative model that integrates Autoregressive (AR) parameterization into…

Signal Processing · Electrical Eng. & Systems 2026-05-19 Kathrin Klein , Benedikt Böck , Nurettin Turan , Wolfgang Utschick

Generalized additive models (GAMs, Hastie & Tibshirani, 1990; Wood, 2017) are an extension of the generalized linear model that allows the effects of covariates to be modelled as smooth functions. GAMs are increasingly used in many areas of…

Computation · Statistics 2024-12-24 Gavin L. Simpson

We propose a partially linear additive Gaussian graphical model (PLA-GGM) for the estimation of associations between random variables distorted by observed confounders. Model parameters are estimated using an $L_1$-regularized maximal…

Machine Learning · Computer Science 2019-06-11 Sinong Geng , Minhao Yan , Mladen Kolar , Oluwasanmi Koyejo

We develop a generalized method of moments (GMM) approach for fast parameter estimation in a new class of Dirichlet latent variable models with mixed data types. Parameter estimation via GMM has been demonstrated to have computational and…

Statistics Theory · Mathematics 2016-03-24 Shiwen Zhao , Barbara E. Engelhardt , Sayan Mukherjee , David B. Dunson

We propose Dirichlet Process mixtures of Generalized Linear Models (DP-GLM), a new method of nonparametric regression that accommodates continuous and categorical inputs, and responses that can be modeled by a generalized linear model. We…

Machine Learning · Statistics 2010-07-16 Lauren A. Hannah , David M. Blei , Warren B. Powell

In multi-state life insurance, an adequate balance between analytic tractability, computational efficiency, and statistical flexibility is of great importance. This might explain the popularity of Markov chain modelling, where matrix…

Probability · Mathematics 2024-04-25 Jamaal Ahmad , Mogens Bladt , Christian Furrer

Multiple cause-of-death data provides a valuable source of information that can be used to enhance health standards by predicting health related trajectories in societies with large populations. These data are often available in large…

Computation and Language · Computer Science 2017-05-11 Hamid Reza Hassanzadeh , Ying Sha , May D. Wang

Longitudinal studies frequently incorporate covariates that evolve over time, creating complex dependence structures between outcomes and predictors. When covariates are time dependent, standard power analysis tools--largely developed for…

Methodology · Statistics 2026-05-29 Niloofar Ramezani , Oliver Hurst

In this paper we propose a new class of Dynamic Mixture Models (DAMMs) being able to sequentially adapt the mixture components as well as the mixture composition using information coming from the data. The information driven nature of the…

Methodology · Statistics 2023-01-12 Leopoldo Catania

Admixture mapping is a popular tool to identify regions of the genome associated with traits in a recently admixed population. Existing methods have been developed primarily for identification of a single locus influencing a dichotomous…

Applications · Statistics 2011-11-24 Bin Zhu , Allison E. Ashley-Koch , David B. Dunson

There is a great need for technologies that can predict the mortality of patients in intensive care units with both high accuracy and accountability. We present joint end-to-end neural network architectures that combine long short-term…

Computation and Language · Computer Science 2017-09-12 Yohan Jo , Lisa Lee , Shruti Palaskar

In modern computer experiment applications, one often encounters the situation where various models of a physical system are considered, each implemented as a simulator on a computer. An important question in such a setting is determining…

Methodology · Statistics 2023-05-08 John C. Yannotty , Thomas J. Santner , Richard J. Furnstahl , Matthew T. Pratola

In various data situations joint models are an efficient tool to analyze relationships between time dependent covariates and event times or to correct for event-dependent dropout occurring in regression analysis. Joint modeling connects a…

Methodology · Statistics 2018-10-25 Colin Griesbach , Andreas Mayr , Elisabeth Waldmann

Assessing climate-driven mortality risk has become an emerging area of research in recent decades. In this paper, we propose a novel approach to explicitly incorporate climate-driven effects into both single- and multi-population stochastic…

Applications · Statistics 2025-06-03 Jiacheng Min , Han Li , Thomas Nagler , Shuanming Li

Many common clustering methods cannot be used for clustering multivariate longitudinal data in cases where variables exhibit high autocorrelations. In this article, a copula kernel mixture model (CKMM) is proposed for clustering data of…

Methodology · Statistics 2025-06-23 Xi Zhang , Orla A. Murphy , Paul D. McNicholas

In this paper, we discuss a family of robust, high-dimensional regression models for quantile and composite quantile regression, both with and without an adaptive lasso penalty for variable selection. We reformulate these quantile…

Computation · Statistics 2020-06-29 Matthew Pietrosanu , Jueyu Gao , Linglong Kong , Bei Jiang , Di Niu

Several mixed-effects models for longitudinal data have been proposed to accommodate the non-linearity of late-life cognitive trajectories and assess the putative influence of covariates on it. No prior research provides a side-by-side…

Applications · Statistics 2024-03-07 Maude Wagner , Donald R. Hedeker , Tianhao Wang , Graciela Muniz-Terrera , Ana W. Capuano

Predicting the evolution of mortality rates plays a central role for life insurance and pension funds.Various stochastic frameworks have been developed to model mortality patterns taking into account the main stylized facts driving these…

Applications · Statistics 2021-11-17 Karim Barigou , Pierre-Olivier Goffard , Stéphane Loisel , Yahia Salhi