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Optic deconvolution in light microscopy (LM) refers to recovering the object details from images, revealing the ground truth of samples. Traditional explicit methods in LM rely on the point spread function (PSF) during image acquisition.…

Quantitative Methods · Quantitative Biology 2026-03-24 Rui Li , Mikhail Kudryashev , Artur Yakimovich

Recent developments in fluorescence microscopy allow capturing high-resolution 3D images over time for living model organisms. To be able to image even large specimens, techniques like multi-view light-sheet imaging record different…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Canyu Yang , Dennis Eschweiler , Johannes Stegmaier

Multi-focus image fusion (MFF) is a popular technique to generate an all-in-focus image, where all objects in the scene are sharp. However, existing methods pay little attention to defocus spread effects of the real-world multi-focus…

Computer Vision and Pattern Recognition · Computer Science 2021-02-02 Shuang Xu , Lizhen Ji , Zhe Wang , Pengfei Li , Kai Sun , Chunxia Zhang , Jiangshe Zhang

The objective of image super-resolution is to reconstruct a high-resolution (HR) image with the prior knowledge from one or several low-resolution (LR) images. However, in the real world, due to the limited complementary information, the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-16 Jing Sun , Qiangqiang Yuan , Huanfeng Shen , Jie Li , Liangpei Zhang

The process of acquiring microscopic images in life sciences often results in image degradation and corruption, characterised by the presence of noise and blur, which poses significant challenges in accurately analysing and interpreting the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Tomáš Chobola , Gesine Müller , Veit Dausmann , Anton Theileis , Jan Taucher , Jan Huisken , Tingying Peng

Volumetric biological imaging often involves compromising high temporal resolution at the expense of high spatial resolution when popular scanning methods are used to capture 3D information. We introduce an integrated experimental and image…

The resolution of optical imaging is classically limited by the width of the point-spread function, which in turn is determined by the Rayleigh length. Recently, spatial-mode demultiplexing (SPADE) has been proposed as a method to achieve…

Quantum Physics · Physics 2025-02-26 Giuseppe Buonaiuto , Cosmo Lupo

Deep-learning (DL)-based image deconvolution (ID) has exhibited remarkable recovery performance, surpassing traditional linear methods. However, unlike traditional ID approaches that rely on analytical properties of the point spread…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Romario Gualdrón-Hurtado , Roman Jacome , Sergio Urrea , Henry Arguello , Luis Gonzalez

We develop a novel algorithm for large-scale holographic reconstruction of 3D particle fields. Our method is based on a multiple-scattering beam propagation method (BPM) combined with sparse regularization that enables recovering dense 3D…

Optics · Physics 2021-05-24 Hao Wang , Waleed Tahir , Jiabei Zhu , Lei Tian

In this paper we study the high-dimensional super-resolution imaging problem. Here we are given an image of a number of point sources of light whose locations and intensities are unknown. The image is pixelized and is blurred by a known…

Optimization and Control · Mathematics 2022-10-19 Bakytzhan Kurmanbek , Elina Robeva

In order to address the issue that medical image would suffer from severe blurring caused by the lack of high-frequency details in the process of image super-resolution reconstruction, a novel medical image super-resolution method based on…

Computer Vision and Pattern Recognition · Computer Science 2019-05-14 Kewen Liu , Yuan Ma , Hongxia Xiong , Zejun Yan , Zhijun Zhou , Panpan Fang , Chaoyang Liu

Accurate and fast 3D imaging of specular surfaces still poses major challenges for state-of-the-art optical measurement principles. Frequently used methods, such as phase-measuring deflectometry (PMD) or shape-from-polarization (SfP), rely…

Computer Vision and Pattern Recognition · Computer Science 2024-06-05 Jiazhang Wang , Oliver Cossairt , Florian Willomitzer

Photomultiplier tubes (PMTs) are widely used as photon sensors for neutrino and dark matter detection. Accurate charge and time information extracted from PMT waveforms is crucial for event reconstruction. An algorithm based on…

Instrumentation and Detectors · Physics 2026-03-23 Xingyi Lin , Jinghuan Xu , Yongbo Huang , Jingzhe Tang , Tianying Xiao , Yingke Li

We propose an image deconvolution algorithm when the data is contaminated by Poisson noise. The image to restore is assumed to be sparsely represented in a dictionary of waveforms such as the wavelet or curvelet transforms. Our key…

Applications · Statistics 2009-11-13 François-Xavier Dupé , Jalal Fadili , Jean Luc Starck

We present STARRED, a Point Spread Function (PSF) reconstruction, two-channel deconvolution, and light curve extraction method designed for high-precision photometric measurements in imaging time series. An improved resolution of the data…

Instrumentation and Methods for Astrophysics · Physics 2024-07-25 Martin Millon , Kevin Michalewicz , Frédéric Dux , Frédéric Courbin , Philip J. Marshall

Accurate blur estimation is essential for high-performance imaging across various applications. Blur is typically represented by the point spread function (PSF). In this paper, we propose a physics-informed PSF learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Liqun Chen , Yuxuan Li , Jun Dai , Jinwei Gu , Tianfan Xue

Deconvolution is the most widely used aberration correction technique in microscopy, however most techniques assume that the aberrations are the same for each point in the image, which is rarely true. Methods for tracking spatially varying…

Optics · Physics 2025-12-02 Jakub Czuchnowski , Chuan Li , Hongli Ni , Brandon Weissbourd , Jerome Mertz

Optical resolution photoacoustic microscopy (OR-PAM) leverages optical focusing and acoustic detection for microscopic optical absorption imaging. Intrinsically it owns high optical lateral resolution and poor acoustic axial resolution.…

Signal Processing · Electrical Eng. & Systems 2023-09-19 Yu-Hsiang Yu , Meng-Lin Li

Methods of three-dimensional deconvolution with a point-spread function as frequently employed in optical microscopy to reconstruct true three-dimensional distribution of objects are extended to holographic reconstructions. Two such schemes…

Optics · Physics 2017-08-09 Tatiana Latychevskaia , Fabian Gehri , Hans-Werner Fink

In the case of ground-based telescopes equipped with adaptive optics systems, the point spread function (PSF) is only poorly known or completely unknown. Moreover, an accurate modeling of the PSF is in general not available. Therefore in…

Numerical Analysis · Mathematics 2015-06-09 M. Prato , A. La Camera , S. Bonettini , S. Rebegoldi , M. Bertero , P. Boccacci