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One of the advantages of spectral computed tomography (CT) is it can achieve accurate material components using the material decomposition methods. The image-based material decomposition is a common method to obtain specific material…

Image and Video Processing · Electrical Eng. & Systems 2019-10-18 Weiwen Wu , Peijun Chen , Vince Vardhanabhuti , Weifei Wu , Hengyong Yu

Material decomposition in X-ray imaging uses the energy-dependence of attenuation to virtually decompose an object into specific constituent materials. X-ray phase contrast imaging is a developing technique that can enhance image contrast…

Dual-energy X-ray Computed Tomography (DECT) constitutes an advanced technology which enables automatic decomposition of materials in clinical images without manual segmentation using the dependency of the X-ray linear attenuation with…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Hang Xu , Alexandre Bousse , Alessandro Perelli

Background: Dual-energy CT (DECT) and material decomposition play vital roles in quantitative medical imaging. However, the decomposition process may suffer from significant noise amplification, leading to severely degraded image…

Multi-energy CT has long demonstrated its ability to enhance image quality with material decomposition. Yet, it has largely been limited to applications that already have high contrast. More recently, x-ray phase-contrast (XPC) imaging has…

Medical Physics · Physics 2025-08-19 Giavanna Jadick , Patrick La Rivière

This paper proposes a novel approach to spectral computed tomography (CT) material decomposition that uses the recent advances in generative diffusion models (DMs) for inverse problems. Spectral CT and more particularly photon-counting CT…

Material decomposition for imaging multiple contrast agents in a single acquisition has been made possible by spectral CT: a modality which incorporates multiple photon energy spectral sensitivities into a single data collection. This work…

Medical Physics · Physics 2020-08-11 Matthew Tivnan , Steven Tilley , J. Webster Stayman

Many spectral CT applications require accurate material decomposition. Existing material decomposition algorithms are often susceptible to significant noise magnification or, in the case of one-step model-based approaches, hampered by slow…

Medical Physics · Physics 2025-07-22 Xiao Jiang , Grace J. Gang , J. Webster Stayman

This study describes a new approach for material decomposition in x-ray imaging, utilising phase contrast to both increase sensitivity to weakly-attenuating samples and to act as a complementary measurement to attenuation, therefore…

X-ray energy spectrum plays an essential role in imaging and related tasks. Due to the high photon flux of clinical CT scanners, most of the spectrum estimation methods are indirect and are usually suffered from various limitations. The…

Medical Physics · Physics 2016-04-19 Wei Zhao , Qiude Zhang , Tianye Niu

Dual-energy computed tomography (CT) is to reconstruct images of an object from two projection datasets generated from two distinct x-ray source energy spectra. It can provide more accurate attenuation quantification than conventional CT…

Medical Physics · Physics 2018-05-15 Wenxiang Cong , Daniel Harrison , Yan Xi , Ge Wang

X-ray energy spectrum plays an essential role in computed tomography (CT) imaging and related tasks. Due to the high photon flux of clinical CT scanners, most of spectrum estimation methods are indirect and usually suffered from various…

Medical Physics · Physics 2017-06-14 Wei Zhao , Lei Xing , Qiude Zhang , Qingguo Xie , Tianye Niu

In this work, we introduce a new deep learning approach based on diffusion posterior sampling (DPS) to perform material decomposition from spectral CT measurements. This approach combines sophisticated prior knowledge from unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2024-02-07 Xiao Jiang , Grace J. Gang , J. Webster Stayman

Computed Tomography (CT) is widely used in engineering and medicine for imaging the interior of objects, patients, or animals. If the employed X-ray source is monoenergetic, image reconstruction essentially means the inversion of a ray…

Optimization and Control · Mathematics 2022-06-08 Georgios Papanikos , Benedikt Wirth

Photon-counting CT (PCCT) offers improved diagnostic performance through better spatial and energy resolution, but developing high-quality image reconstruction methods that can deal with these large datasets is challenging. Model-based…

Medical Physics · Physics 2022-08-09 Alma Eguizabal , Ozan Öktem , Mats U. Persson

Dual-energy computed tomography (DECT) enables material-specific imaging through acquisitions at two different X-ray energy spectra. Material decomposition from DECT data is an ill-posed inverse problem that is highly sensitive to noise…

Dual-energy computed tomography (DECT) has been widely used to obtain quantitative elemental composition of imaged subjects for personalized and precise medical diagnosis. Compared with DECT leveraging advanced X-ray source and/or detector…

Medical Physics · Physics 2024-08-28 Qiaoxin Li , Ruifeng Chen , Peng Wang , Guotao Quan , Yanfeng Du , Dong Liang , Yinsheng Li

Spectral photon-counting X-ray CT (sCT) opens up new possibilities for the quantitative measurement of materials in an object, compared to conventional energy-integrating CT or dual energy CT. However, achieving reliable and accurate…

Image and Video Processing · Electrical Eng. & Systems 2020-07-15 Bingqing Xie , Pei Niu , Ting Su , Valérie Kaftandjian , Loic Boussel , Philippe Douek Feng Yang , Philippe Duvauchelle , Yuemin Zhu

Dual energy CT (DECT) enhances tissue characterization because it can produce images of basis materials such as soft-tissue and bone. DECT is of great interest in applications to medical imaging, security inspection and nondestructive…

Medical Physics · Physics 2018-09-05 Qiaoqiao Ding , Tianye Niu , Xiaoqun Zhang , Yong Long

By acquiring two sets of tomographic measurements at distinct X-ray spectra, the dual-energy CT (DECT) enables quantitative material-specific imaging. However, the conventionally decomposed material basis images may encounter severe image…

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