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Fundamental understanding of the effect of microscopic parameters on the dynamics of probe particles in different complex environments has wide implications. Examples include diffusion of proteins in the biological hydrogels, porous media,…

Soft Condensed Matter · Physics 2019-09-11 Praveen Kumar , Ligesh Theeyancheri , Subhasish Chaki , Rajarshi Chakrabarti

Aims. Numerical test-particle simulations are a reliable and frequently used tool to test analytical transport theories and to predict mean-free paths. The comparison between solutions of the diffusion equation and the particle flux is used…

High Energy Astrophysical Phenomena · Physics 2016-02-17 R. C. Tautz , J. Bolte , A. Shalchi

We propose a model for the motion of a single active particle in a heterogeneous environment where the heterogeneity may arise due to the crowding, conformational fluctuations and/or slow rearrangement of the surroundings. Describing the…

Statistical Mechanics · Physics 2022-03-04 Koushik Goswami , Rajarshi Chakrabarti

Collectively coordinated cell migration plays a role in tissue embryogenesis, cancer, homeostasis and healing. To study these processes, different cell-based modelling approaches have been developed, ranging from lattice-based cellular…

Soft Condensed Matter · Physics 2023-05-19 Carine P. Beatrici , Cassio A. Kirch , Silke Henkes , François Graner , Leonardo G. Brunnet

The use of probe molecules to extract the local dynamical and structural properties of complex dynamical systems is an age-old technique both in simulations and experiments. A lot of important information which is not immediately accessible…

Soft Condensed Matter · Physics 2021-03-30 Anoop Mutneja , Smarajit Karmakar

Despite decades of research, the modeling of moving contact lines has remained a formidable challenge in fluid dynamics whose resolution will impact numerous industrial, biological, and daily life applications. On the one hand, molecular…

Soft Condensed Matter · Physics 2018-11-09 E. R. Smith , P. E. Theodorakis , R. V. Craster , O. K. Matar

Simulation ensembles are a common tool in physics for understanding how a model outcome depends on input parameters. We analyze an active particle system, where each particle can use energy from its surroundings to propel itself. A…

Human-Computer Interaction · Computer Science 2023-03-21 Marina Evers , Raphael Wittkowski , Lars Linsen

Molecular dynamics (MD) has become a powerful tool for studying biophysical systems, due to increasing computational power and availability of software. Although MD has made many contributions to better understanding these complex…

Computational Physics · Physics 2019-09-27 Yihang Wang , Joao Marcelo Lamim Ribeiro , Pratyush Tiwary

Cell motility in dense cell collectives is pivotal in various diseases like cancer metastasis and asthma. A central aspect in these phenomena is the heterogeneity in cell motility, but identifying the motility of individual cells is…

Several important aspects of software product quality can be evaluated using dynamic metrics that effectively capture and reflect the software's true runtime behavior. While the extent of research in this field is still relatively limited,…

Software Engineering · Computer Science 2021-01-12 Amjed Tahir , Stephen G. MacDonell

Cell motility is one of the most fundamental phenomena underlying biological processes that maintain living organisms alive. Here we introduce a simple model to describe the motility of cells which include not only time-correlated internal…

Biological Physics · Physics 2022-07-13 T. N. Azevedo , L. G. Rizzi

The evaluation of collective modes is fundamental in the analysis of molecular dynamics simulations. Several methods are available to extract that information, i.e normal mode analysis, principal component and spectral analysis of…

Computational Physics · Physics 2017-09-11 Vito Dario Camiola , Valentina Tozzini

Particle-in-cell methods with stochastic collision models are commonly used to simulate collisional plasma dynamics, with applications ranging from hypersonic flight to semiconductor manufacturing. Code verification of such methods is…

Computational Physics · Physics 2026-05-26 Brian A. Freno , William J. McDoniel , Christopher H. Moore , Neil R. Matula

Theoretical and experimental investigations of water vapor interaction with porous materials are carried out both at the macro level and at the micro level. At the macro level, the influence of the arrangement structure of individual pores…

Fluid Dynamics · Physics 2018-05-08 E. G. Nikonov , M. Pavluš , M. Popovičová

We present an effective method for estimating the motion of proteins from the motion of attached probe particles in single-molecule experiments. The framework naturally incorporates Langevin dynamics to compute the most probable trajectory…

Chemical Physics · Physics 2015-05-20 Makito Miyazaki , Takahiro Harada

Quantifying the outcomes of cells collisions is a crucial step in building the foundations of a kinetic theory of living matter. Here, we develop a mechanical theory of such collisions by first representing individual cells as extended…

Biological Physics · Physics 2019-12-11 Pierre Recho , Thibaut Putelat , Lev Truskinovsky

Active particles contain internal degrees of freedom with the ability to take in and dissipate energy and, in the process, execute systematic movement. Examples include all living organisms and their motile constituents such as molecular…

Soft Condensed Matter · Physics 2015-05-18 Sriram Ramaswamy

The chemical behaviour of single metal atoms largely depends on the local coordination environment, including interactions with the substrate and with the surrounding gas or liquid. However, the key instrumentation for studying such systems…

The ability of many living systems to actively self-propel underlies critical biomedical, environmental, and industrial processes. While such active transport is well-studied in uniform settings, environmental complexities such as geometric…

Biological Physics · Physics 2021-08-23 Alejandro Martínez-Calvo , Carolina Trenado-Yuste , Sujit S. Datta

Migration of cells can be characterized by two, prototypical types of motion: individual and collective migration. We propose a statistical-inference approach designed to detect the presence of cell-cell interactions that give rise to…

Cell Behavior · Quantitative Biology 2020-03-13 Elena Agliari , Pablo J. Sáez , Adriano Barra , Matthieu Piel , Pablo Vargas , Michele Castellana