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Purpose: Recent developments in computational pathology have been driven by advances in Vision Foundation Models, particularly the Segment Anything Model (SAM). This model facilitates nuclei segmentation through two primary methods:…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Xueyuan Li , Can Cui , Ruining Deng , Yucheng Tang , Quan Liu , Tianyuan Yao , Shunxing Bao , Naweed Chowdhury , Haichun Yang , Yuankai Huo

Vision foundation models like the Segment Anything Model (SAM), pretrained on large-scale natural image datasets, often struggle in medical image segmentation due to a lack of domain-specific adaptation. In clinical practice, fine-tuning…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Zelin Liu , Sicheng Dong , Bocheng Li , Yixuan Yang , Jiacheng Ruan , Chenxu Zhou , Suncheng Xiang

Semi-supervised learning (SSL) has achieved notable progress in medical image segmentation. To achieve effective SSL, a model needs to be able to efficiently learn from limited labeled data and effectively exploiting knowledge from abundant…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Juzheng Miao , Cheng Chen , Keli Zhang , Jie Chuai , Quanzheng Li , Pheng-Ann Heng

The Segment Anything Model (SAM) serves as a fundamental model for semantic segmentation and demonstrates remarkable generalization capabilities across a wide range of downstream scenarios. In this empirical study, we examine SAM's…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 An Wang , Mobarakol Islam , Mengya Xu , Yang Zhang , Hongliang Ren

The Segment Anything Model (SAM) exhibits impressive capabilities in zero-shot segmentation for natural images. Recently, SAM has gained a great deal of attention for its applications in medical image segmentation. However, to our best…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Pengfei Gu , Zihan Zhao , Hongxiao Wang , Yaopeng Peng , Yizhe Zhang , Nishchal Sapkota , Chaoli Wang , Danny Z. Chen

Segmentation is vital for ophthalmology image analysis. But its various modal images hinder most of the existing segmentation algorithms applications, as they rely on training based on a large number of labels or hold weak generalization…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Zhongxi Qiu , Yan Hu , Heng Li , Jiang Liu

The Segment Anything Model (SAM) is a new image segmentation tool trained with the largest available segmentation dataset. The model has demonstrated that, with prompts, it can create high-quality masks for general images. However, the…

Image and Video Processing · Electrical Eng. & Systems 2024-02-06 Yihao Liu , Jiaming Zhang , Zhangcong She , Amir Kheradmand , Mehran Armand

Automated segmentation is a fundamental medical image analysis task, which enjoys significant advances due to the advent of deep learning. While foundation models have been useful in natural language processing and some vision tasks for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Hanxue Gu , Haoyu Dong , Jichen Yang , Maciej A. Mazurowski

The recently released Segment Anything Model (SAM) has shown powerful zero-shot segmentation capabilities through a semi-automatic annotation setup in which the user can provide a prompt in the form of clicks or bounding boxes. There is…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Benjamin Towle , Xin Chen , Ke Zhou

We propose a straightforward yet highly effective few-shot fine-tuning strategy for adapting the Segment Anything (SAM) to anatomical segmentation tasks in medical images. Our novel approach revolves around reformulating the mask decoder…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Weiyi Xie , Nathalie Willems , Shubham Patil , Yang Li , Mayank Kumar

Segment Anything (SAM) has recently pushed the boundaries of segmentation by demonstrating zero-shot generalization and flexible prompting after training on over one billion masks. Despite this, its mask prediction accuracy often falls…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Zezhong Fan , Xiaohan Li , Topojoy Biswas , Kaushiki Nag , Kannan Achan

In this study, we evaluate the performance of the Segment Anything Model (SAM) in clinical radiotherapy. Our results indicate that SAM's 'segment anything' mode can achieve clinically acceptable segmentation results in most organs-at-risk…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Lian Zhang , Zhengliang Liu , Lu Zhang , Zihao Wu , Xiaowei Yu , Jason Holmes , Hongying Feng , Haixing Dai , Xiang Li , Quanzheng Li , Dajiang Zhu , Tianming Liu , Wei Liu

Weakly supervised instance segmentation using only bounding box annotations has recently attracted much research attention. Most of the current efforts leverage low-level image features as extra supervision without explicitly exploiting the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Ruihuang Li , Chenhang He , Yabin Zhang , Shuai Li , Liyi Chen , Lei Zhang

The development of high quality medical image segmentation algorithms depends on the availability of large datasets with pixel-level labels. The challenges of collecting such datasets, especially in case of 3D volumes, motivate to develop…

Computer Vision and Pattern Recognition · Computer Science 2021-08-10 Ekaterina Redekop , Alexey Chernyavskiy

The Segment Anything Model (SAM) is a powerful foundation model that introduced revolutionary advancements in natural image segmentation. However, its performance remains sub-optimal when delineating the intricate structure of biomedical…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Xiangru Li , Yifei Zhang , Liang Zhao

Medical image segmentation is a key task in the imaging workflow, influencing many image-based decisions. Traditional, fully-supervised segmentation models rely on large amounts of labeled training data, typically obtained through manual…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Tyler Ward , Meredith K. Owen , O'Kira Coleman , Brian Noehren , Abdullah-Al-Zubaer Imran

Segmentation of anatomical structures and pathological regions in medical images is essential for modern clinical diagnosis, disease research, and treatment planning. While significant advancements have been made in deep learning-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Taha Koleilat , Hojat Asgariandehkordi , Hassan Rivaz , Yiming Xiao

Robust and accurate segmentation of scenes has become one core functionality in various visual recognition and navigation tasks. This has inspired the recent development of Segment Anything Model (SAM), a foundation model for general mask…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Aoran Xiao , Weihao Xuan , Heli Qi , Yun Xing , Naoto Yokoya , Shijian Lu

Accurate tumor segmentation and classification in breast ultrasound (BUS) imaging remain challenging due to low contrast, speckle noise, and diverse lesion morphology. This study presents a multi-task deep learning framework that jointly…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Samuel E. Johnny , Bernes L. Atabonfack , Israel Alagbe , Assane Gueye

Radiological images such as computed tomography (CT) and X-rays render anatomy with intrinsic structures. Being able to reliably locate the same anatomical structure across varying images is a fundamental task in medical image analysis. In…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Ke Yan , Jinzheng Cai , Dakai Jin , Shun Miao , Dazhou Guo , Adam P. Harrison , Youbao Tang , Jing Xiao , Jingjing Lu , Le Lu
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