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Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique that provides high-resolution cross-sectional images of the retina, which are useful for diagnosing and monitoring various retinal diseases. However, manual…
Optical link tomography (OLT) is a rapidly evolving field that allows the multi-span, end-to-end visualization of optical power along fiber links in multiple dimensions from network endpoints, solely by processing signals received at…
Localization-based imaging has revolutionized fluorescence optical microscopy and has also enabled unprecedented ultrasound images of microvascular structures in deep tissues. Herein, we introduce a new concept of localization optoacoustic…
The intensity levels allowed by safety standards (ANSI or ICNIRP) limit the amount of light that can be used in a clinical setting to image highly scattering or absorptive tissues with Optical Coherence Tomography (OCT). To achieve…
High-resolution Optical Coherence Tomography (OCT) images are crucial for ophthalmology studies but are limited by their relatively narrow field of view (FoV). Image mosaicking is a technique for aligning multiple overlapping images to…
The optic nerve head represents the intraocular section of the optic nerve (ONH), which is prone to damage by intraocular pressure. The advent of optical coherence tomography (OCT) has enabled the evaluation of novel optic nerve head…
Optical-coherence tomography (OCT) is a technique that employs light in order to measure the internal structure of semi-transparent, e.g. biological, samples. It is based on the interference pattern of low-coherence light. Quantum-OCT…
We apply three optical coherence tomography (OCT) image analysis techniques to extract morphometric information from OCT images obtained on peripheral nerves of rat. The accuracy of each technique is evaluated against histological…
Measurement of local temperature using label-free optical methods has gained importance as a pivotal tool in both fundamental and applied research. Yet, most of these approaches are limited to steady-state measurements of planar heat…
Retinal optical coherence tomography (OCT) and OCT angiography (OCTA) suffer from the degeneration of image quality due to speckle noise and bulk-motion noise, respectively. Because the cross-sectional retina has distinct features in OCT…
Non-contact measurement of the refractive index and thickness of multilayer biological tissues is of great significance for biomedical applications and can greatly improve medical diagnosis and treatment. In this work, we introduce a…
Objective: The advent of Electronic Medical Records (EMR) with large electronic imaging databases along with advances in deep neural networks with machine learning has provided a unique opportunity to achieve milestones in automated image…
Retinal optical coherence tomography (OCT) images provide crucial insights into the health of the posterior ocular segment. Therefore, the advancement of automated image analysis methods is imperative to equip clinicians and researchers…
The highest three-dimensional (3D) resolution possible in in-vivo retinal imaging is achieved by combining optical coherence tomography (OCT) and adaptive optics (AO). However, this combination brings important limitations, such as small…
Optical Coherence Tomography (OCT) provides high-resolution, 3D, and non-invasive visualization of retinal layers in vivo, serving as a critical tool for lesion localization and disease diagnosis. However, its widespread adoption is limited…
Automatic and accurate segmentation for retinal and choroidal layers of Optical Coherence Tomography (OCT) is crucial for detection of various ocular diseases. However, because of the variations in different equipments, OCT data obtained…
Acousto-optic tomography (AOT) enables optical-contrast imaging deep inside scattering samples via localized ultrasound modulation of scattered light. However, the resolution of AOT is inherently limited by the ultrasound focus size,…
Cardiovascular diseases (CVD) are the leading cause of death globally. Non-invasive, cost-effective imaging techniques play a crucial role in early detection and prevention of CVD. Optical coherence tomography (OCT) has gained recognition…
Whole-eye optical coherence tomography (WEOCT) has emerged as a transformative imaging modality capable of simultaneously capturing the anterior and posterior segments of the human eye. WEOCT enables comprehensive ocular biometry, which is…
Eye diseases are common in older Americans and can lead to decreased vision and blindness. Recent advancements in imaging technologies allow clinicians to capture high-quality images of the retinal blood vessels via Optical Coherence…