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Related papers: FedECA: Federated External Control Arms for Causal…

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Clustered Federated Learning has emerged as an effective approach for handling heterogeneous data across clients by partitioning them into clusters with similar or identical data distributions. However, most existing methods, including the…

Machine Learning · Computer Science 2026-03-03 Jonas Kirch , Sebastian Becker , Tiago Koketsu Rodrigues , Stefan Harmeling

We are interested in estimating the effect of a treatment applied to individuals at multiple sites, where data is stored locally for each site. Due to privacy constraints, individual-level data cannot be shared across sites; the sites may…

Machine Learning · Computer Science 2023-04-04 Ruoxuan Xiong , Allison Koenecke , Michael Powell , Zhu Shen , Joshua T. Vogelstein , Susan Athey

Federated Learning enables visual models to be trained on-device, bringing advantages for user privacy (data need never leave the device), but challenges in terms of data diversity and quality. Whilst typical models in the datacenter are…

Machine Learning · Computer Science 2020-07-20 Tzu-Ming Harry Hsu , Hang Qi , Matthew Brown

Federated learning is an approach to collaboratively training machine learning models for multiple parties that prohibit data sharing. One of the challenges in federated learning is non-IID data between clients, as a single model can not…

Machine Learning · Computer Science 2023-08-08 Peng Lan , Donglai Chen , Chong Xie , Keshu Chen , Jinyuan He , Juntao Zhang , Yonghong Chen , Yan Xu

Federated causal inference enables multi-site treatment effect estimation without sharing individual-level data, offering a privacy-preserving solution for real-world evidence generation. However, data heterogeneity across sites, manifested…

Machine Learning · Computer Science 2025-05-06 Haoyang Li , Jie Xu , Kyra Gan , Fei Wang , Chengxi Zang

Availability of large, diverse, and multi-national datasets is crucial for the development of effective and clinically applicable AI systems in the medical imaging domain. However, forming a global model by bringing these datasets together…

Machine Learning · Computer Science 2022-09-07 Ece Isik-Polat , Gorkem Polat , Altan Kocyigit , Alptekin Temizel

To date, the most popular federated learning algorithms use coordinate-wise averaging of the model parameters. We depart from this approach by differentiating client contributions according to the performance of local learning and its…

Machine Learning · Computer Science 2022-05-31 Adnan Ben Mansour , Gaia Carenini , Alexandre Duplessis , David Naccache

Machine learning has become integral to medical research and is increasingly applied in clinical settings to support diagnosis and decision-making; however, its effectiveness depends on access to large, diverse datasets, which are limited…

Machine Learning · Computer Science 2026-04-21 Ke Wan , Kensuke Tanioka , Toshio Shimokawa

It is increasingly common to augment randomized controlled trial with external controls from observational data, to evaluate the treatment effect of an intervention. Traditional approaches to treatment effect estimation involve ambiguous…

Methodology · Statistics 2025-03-28 Bo Liu , Laine Thomas , Rury R. Holman , Fan Li

Leveraging external controls -- relevant individual patient data under control from external trials or real-world data -- has the potential to reduce the cost of randomized controlled trials (RCTs) while increasing the proportion of trial…

Methodology · Statistics 2022-07-13 Yanyao Yi , Ying Zhang , Yu Du , Ting Ye

With the rapid development of the Internet of Things (IoT), AI model training on private data such as human sensing data is highly desired. Federated learning (FL) has emerged as a privacy-preserving distributed training framework for this…

Machine Learning · Computer Science 2026-01-27 Kaile Wang , Jiannong Cao , Yu Yang , Xiaoyin Li , Yinfeng Cao

Analyzing data from multiple sources offers valuable opportunities to improve the estimation efficiency of causal estimands. However, this analysis also poses many challenges due to population heterogeneity and data privacy constraints.…

Methodology · Statistics 2025-10-23 Rong Zhao , Jason Falvey , Xu Shi , Vernon M. Chinchilli , Chixiang Chen

Chemistry research has both high material and computational costs to conduct experiments. Institutions thus consider chemical data to be valuable and there have been few efforts to construct large public datasets for machine learning.…

Machine Learning · Computer Science 2022-05-10 Wei Zhu , Jiebo Luo , Andrew White

This paper studies inference on treatment effects in panel data settings with unobserved confounding. We model outcome variables through a factor model with random factors and loadings. Such factors and loadings may act as unobserved…

Econometrics · Economics 2023-12-05 Guido W. Imbens , Davide Viviano

Estimating counterfactual outcomes over time has the potential to unlock personalized healthcare by assisting decision-makers to answer ''what-iF'' questions. Existing causal inference approaches typically consider regular, discrete-time…

Machine Learning · Computer Science 2022-06-17 Nabeel Seedat , Fergus Imrie , Alexis Bellot , Zhaozhi Qian , Mihaela van der Schaar

Partially class-disjoint data (PCDD), a common yet under-explored data formation where each client contributes a part of classes (instead of all classes) of samples, severely challenges the performance of federated algorithms. Without full…

Machine Learning · Computer Science 2024-05-30 Ziqing Fan , Ruipeng Zhang , Jiangchao Yao , Bo Han , Ya Zhang , Yanfeng Wang

Counterfactual estimation over time is important in various applications, such as personalized medicine. However, time-dependent confounding bias in observational data still poses a significant challenge in achieving accurate and efficient…

Machine Learning · Computer Science 2026-03-13 Nghia D. Nguyen , Pablo Robles-Granda , Lav R. Varshney

Federated learning (FL) systems are susceptible to attacks from malicious actors who might attempt to corrupt the training model through various poisoning attacks. FL also poses new challenges in addressing group bias, such as ensuring fair…

Machine Learning · Computer Science 2023-06-08 Viktor Valadi , Xinchi Qiu , Pedro Porto Buarque de Gusmão , Nicholas D. Lane , Mina Alibeigi

Federated Learning (FL) enables distributed Artificial Intelligence (AI) across cloud-edge environments by allowing collaborative model training without centralizing data. In cross-device deployments, FL systems face strict communication…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-11 Daniel M. Jimenez-Gutierrez , Giovanni Giunta , Mehrdad Hassanzadeh , Aris Anagnostopoulos , Ioannis Chatzigiannakis , Andrea Vitaletti

In the field of brain science, data sharing across servers is becoming increasingly challenging due to issues such as industry competition, privacy security, and administrative procedure policies and regulations. Therefore, there is an…

Numerical Analysis · Mathematics 2024-04-19 Yukai Cai , Hang Liu , Xiulin Wang , Hongjin Li , Ziyi Wang , Chuanshuai Yang , Fengyu Cong