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Large language models (LLMs) have demonstrated remarkable capabilities in natural language understanding, reasoning, and problem-solving across various domains. However, their ability to perform complex, multi-step reasoning task-essential…

Prompt-based fine-tuning for pre-trained models has proven effective for many natural language processing tasks under few-shot settings in general domain. However, tuning with prompt in biomedical domain has not been investigated…

Computation and Language · Computer Science 2023-04-17 Haochun Wang , Chi Liu , Nuwa Xi , Sendong Zhao , Meizhi Ju , Shiwei Zhang , Ziheng Zhang , Yefeng Zheng , Bing Qin , Ting Liu

Prompt engineering is a crucial yet challenging task for optimizing the performance of large language models (LLMs) on customized tasks. This pioneering research introduces the Automatic Prompt Engineering Toolbox (APET), which enables…

Computation and Language · Computer Science 2024-07-17 Daan Kepel , Konstantina Valogianni

Recent studies have made remarkable progress in histopathology classification. Based on current successes, contemporary works proposed to further upgrade the model towards a more generalizable and robust direction through incrementally…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Yu Zhu , Kang Li , Lequan Yu , Pheng-Ann Heng

Large language models (LLMs) have demonstrated increasingly sophisticated performance in medical and other fields of knowledge. Traditional methods of creating specialist LLMs require extensive fine-tuning and training of models on large…

Computation and Language · Computer Science 2025-02-25 Sean Wu , Michael Koo , Fabien Scalzo , Ira Kurtz

The introduction of large language models (LLMs) has enhanced automation in software engineering tasks, including in Model Driven Engineering (MDE). However, using general-purpose LLMs for domain modeling has its limitations. One approach…

Software Engineering · Computer Science 2025-07-22 Vladyslav Bulhakov , Giordano d'Aloisio , Claudio Di Sipio , Antinisca Di Marco , Davide Di Ruscio

Time series foundation models are pre-trained on large datasets and are able to achieve state-of-the-art performance in diverse tasks. However, to date, there has been limited work demonstrating how well these models perform in medical…

Machine Learning · Computer Science 2024-11-21 Mingzhu Liu , Angela H. Chen , George H. Chen

Pre-trained models have been shown effective in many code intelligence tasks. These models are pre-trained on large-scale unlabeled corpus and then fine-tuned in downstream tasks. However, as the inputs to pre-training and downstream tasks…

Software Engineering · Computer Science 2022-07-26 Chaozheng Wang , Yuanhang Yang , Cuiyun Gao , Yun Peng , Hongyu Zhang , Michael R. Lyu

Large language models (LLMs) have shown great potential in medical question answering (MedQA), yet adapting them to biomedical reasoning remains challenging due to domain-specific complexity and limited supervision. In this work, we study…

Computation and Language · Computer Science 2025-11-12 Chenqian Le , Ziheng Gong , Chihang Wang , Haowei Ni , Panfeng Li , Xupeng Chen

Foundation models are large-scale machine learning models that are pre-trained on massive amounts of data and can be adapted for various downstream tasks. They have been extensively applied to tasks in Natural Language Processing and…

We introduce Scaffold Prompt Tuning (ScaPT), a novel prompt-based framework for adapting large-scale functional magnetic resonance imaging (fMRI) pre-trained models to downstream tasks, with high parameter efficiency and improved…

Neurons and Cognition · Quantitative Biology 2024-08-21 Zijian Dong , Yilei Wu , Zijiao Chen , Yichi Zhang , Yueming Jin , Juan Helen Zhou

Recent advances in prompt optimization have notably enhanced the performance of pre-trained language models (PLMs) on downstream tasks. However, the potential of optimized prompts on domain generalization has been under-explored. To explore…

Computation and Language · Computer Science 2024-10-22 Chengzhengxu Li , Xiaoming Liu , Zhaohan Zhang , Yichen Wang , Chen Liu , Yu Lan , Chao Shen

The progress in natural language processing (NLP) using large language models (LLMs) has greatly improved patient information extraction from clinical narratives. However, most methods based on the fine-tuning strategy have limited transfer…

Computation and Language · Computer Science 2024-03-20 Cheng Peng , Zehao Yu , Kaleb E Smith , Wei-Hsuan Lo-Ciganic , Jiang Bian , Yonghui Wu

Recent advancements in large language models, such as GPT-4, have demonstrated remarkable capabilities in processing standard queries. Despite these advancements, their performance substantially declines in \textbf{advanced mathematical…

Artificial Intelligence · Computer Science 2024-07-24 Bin Lei , Yi Zhang , Shan Zuo , Ali Payani , Caiwen Ding

Large language models (LLMs) have shown remarkable performance on many tasks in different domains. However, their performance in closed-book biomedical machine reading comprehension (MRC) has not been evaluated in depth. In this work, we…

Computation and Language · Computer Science 2024-10-28 Shubham Vatsal , Ayush Singh

GPT-3 and several other language models (LMs) can effectively address various natural language processing (NLP) tasks, including machine translation and text summarization. Recently, they have also been successfully employed in the business…

Artificial Intelligence · Computer Science 2023-04-17 Kiran Busch , Alexander Rochlitzer , Diana Sola , Henrik Leopold

Prompt learning is a new paradigm in the Natural Language Processing (NLP) field which has shown impressive performance on a number of natural language tasks with common benchmarking text datasets in full, few-shot, and zero-shot…

Computation and Language · Computer Science 2022-05-12 Niall Taylor , Yi Zhang , Dan Joyce , Alejo Nevado-Holgado , Andrey Kormilitzin

Large language models (LLMs) and prompt engineering hold significant potential for advancing computer programming education through personalized instruction. This paper explores this potential by investigating three critical research…

Artificial Intelligence · Computer Science 2024-07-09 Tianyu Wang , Nianjun Zhou , Zhixiong Chen

Molecular representation learning is crucial for the problem of molecular property prediction, where graph neural networks (GNNs) serve as an effective solution due to their structure modeling capabilities. Since labeled data is often…

Machine Learning · Computer Science 2023-09-26 Cameron Diao , Kaixiong Zhou , Zirui Liu , Xiao Huang , Xia Hu

Foundation models pre-trained on large-scale data have been widely witnessed to achieve success in various natural imaging downstream tasks. Parameter-efficient fine-tuning (PEFT) methods aim to adapt foundation models to new domains by…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Wenqiang Zu , Shenghao Xie , Qing Zhao , Guoqi Li , Lei Ma