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Tackling pattern recognition problems in areas such as computer vision, bioinformatics, speech or text recognition is often done best by taking into account task-specific statistical relations between output variables. In structured…

Machine Learning · Statistics 2016-03-14 Rein Houthooft , Filip De Turck

Prediction of one-dimensional protein structures such as secondary structures and contact numbers is useful for the three-dimensional structure prediction and important for the understanding of sequence-structure relationship. Here we…

Biomolecules · Quantitative Biology 2007-05-23 Akira R. Kinjo , Ken Nishikawa

Background: Deep learning techniques, particularly neural networks, have revolutionized computational physics, offering powerful tools for solving complex partial differential equations (PDEs). However, ensuring stability and efficiency…

Artificial Intelligence · Computer Science 2024-07-11 A. Noorizadegan , R. Cavoretto , D. L. Young , C. S. Chen

User response prediction is a crucial component for personalized information retrieval and filtering scenarios, such as recommender system and web search. The data in user response prediction is mostly in a multi-field categorical format…

Information Retrieval · Computer Science 2018-07-03 Yanru Qu , Bohui Fang , Weinan Zhang , Ruiming Tang , Minzhe Niu , Huifeng Guo , Yong Yu , Xiuqiang He

Protein secondary structure prediction (PSSP) is essential for protein function analysis. However, for low homologous proteins, the PSSP suffers from insufficient input features. In this paper, we explicitly import external self-supervised…

Quantitative Methods · Quantitative Biology 2021-08-10 Qin Wang , Jun Wei , Boyuan Wang , Zhen Li1 , Sheng Wang , Shuguang Cu

Beta-turn prediction is useful in protein function studies and experimental design. Although recent approaches using machine-learning techniques such as SVM, neural networks, and K-NN have achieved good results for beta-turn pre-diction,…

Biomolecules · Quantitative Biology 2018-08-14 Chao Fang , Yi Shang , Dong Xu

Deep neural networks dominate modern machine learning, while alternative function approximators remain comparatively underexplored at scale. In this work, we revisit kernel methods as drop-in components for standard deep learning pipelines.…

Machine Learning · Computer Science 2026-05-05 Jean-Marc Mercier , Gabriele Santin

Nowadays we witness a miniaturisation trend in the semiconductor industry backed up by groundbreaking discoveries and designs in nanoscale characterisation and fabrication. To facilitate the trend and produce ever smaller, faster and…

Neural and Evolutionary Computing · Computer Science 2021-03-30 Karolos-Alexandros Tsakalos , Georgios Ch. Sirakoulis , Andrew Adamatzky , Jim Smith

Support vector machines (SVMs) are widely used and constitute one of the best examined and used machine learning models for two-class classification. Classification in SVM is based on a score procedure, yielding a deterministic…

Machine Learning · Statistics 2023-10-11 Sandra Benítez-Peña , Rafael Blanquero , Emilio Carrizosa , Pepa Ramírez-Cobo

Motivated by the problem of learning with small sample sizes, this paper shows how to incorporate into support-vector machines (SVMs) those properties that have made convolutional neural networks (CNNs) successful. Particularly important is…

Machine Learning · Computer Science 2022-10-25 Tao Liu , P. R. Kumar , Ruida Zhou , Xi Liu

Any applied mathematical model contains parameters. The paper proposes to use kernel learning for the parametric analysis of the model. The approach consists in setting a distribution on the parameter space, obtaining a finite training…

Optimization and Control · Mathematics 2025-01-27 Vladimir Norkin , Alois Pichler

In this work, we design a machine learning based method, online adaptive primal support vector regression (SVR), to model the implied volatility surface (IVS). The algorithm proposed is the first derivation and implementation of an online…

Machine Learning · Statistics 2018-06-08 Yaxiong Zeng , Diego Klabjan

Motivation: In a predictive modeling setting, if sufficient details of the system behavior are known, one can build and use a simulation for making predictions. When sufficient system details are not known, one typically turns to machine…

Machine Learning · Statistics 2019-08-14 Timo M. Deist , Andrew Patti , Zhaoqi Wang , David Krane , Taylor Sorenson , David Craft

We develop scalable randomized kernel methods for jointly associating data from multiple sources and simultaneously predicting an outcome or classifying a unit into one of two or more classes. The proposed methods model nonlinear…

Methodology · Statistics 2023-04-11 Sandra E. Safo , Han Lu

Recommender Systems (RS) shape the filtering and curation of online content, yet we have limited understanding of how predictable their recommendation outputs are. We propose data-driven metrics that quantify the predictability of…

Information Retrieval · Computer Science 2026-04-01 Andrés Abeliuk , Alfonso Valderrama , Simón Campos , Marcelo Mendoza

This article proposes a performance analysis of kernel least squares support vector machines (LS-SVMs) based on a random matrix approach, in the regime where both the dimension of data $p$ and their number $n$ grow large at the same rate.…

Machine Learning · Statistics 2016-09-09 Zhenyu Liao , Romain Couillet

The need for consistent treatment of uncertainty has recently triggered increased interest in probabilistic deep learning methods. However, most current approaches have severe limitations when it comes to inference, since many of these…

A novel kernel-based support vector machine (SVM) for graph classification is proposed. The SVM feature space mapping consists of a sequence of graph convolutional layers, which generates a vector space representation for each vertex,…

Machine Learning · Computer Science 2020-08-05 Padraig Corcoran

The problem of determining which nucleotides of an RNA sequence are paired or unpaired in the secondary structure of an RNA, which we call RNA state inference, can be studied by different machine learning techniques. Successful state…

Biomolecules · Quantitative Biology 2024-07-09 Devin Willmott , David Murrugarra , Qiang Ye

Machine learning is capable of discriminating phases of matter, and finding associated phase transitions, directly from large data sets of raw state configurations. In the context of condensed matter physics, most progress in the field of…

Statistical Mechanics · Physics 2017-12-06 Pedro Ponte , Roger G. Melko