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Related papers: Unleashing the Power of Prompt-driven Nucleus Inst…

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Segment Anything Model (SAM), a prompt-driven foundation model for natural image segmentation, has demonstrated impressive zero-shot performance. However, SAM does not work when directly applied to medical image segmentation, since SAM…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Bin Xie , Hao Tang , Bin Duan , Dawen Cai , Yan Yan , Gady Agam

Large foundation models, known for their strong zero-shot generalization, have excelled in visual and language applications. However, applying them to medical image segmentation, a domain with diverse imaging types and target labels,…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Junde Wu , Jiayuan Zhu , Yueming Jin , Min Xu

Training segmentation models for medical images continues to be challenging due to the limited availability of data annotations. Segment Anything Model (SAM) is a foundation model that is intended to segment user-defined objects of interest…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Maciej A. Mazurowski , Haoyu Dong , Hanxue Gu , Jichen Yang , Nicholas Konz , Yixin Zhang

End-to-end medical image segmentation is of great value for computer-aided diagnosis dominated by task-specific models, usually suffering from poor generalization. With recent breakthroughs brought by the segment anything model (SAM) for…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Xian Lin , Yangyang Xiang , Li Yu , Zengqiang Yan

Segment Anything Model (SAM) has gained significant recognition in the field of semantic segmentation due to its versatile capabilities and impressive performance. Despite its success, SAM faces two primary limitations: (1) it relies…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Yuchen Li , Li Zhang , Youwei Liang , Pengtao Xie

Recently, foundation models trained on massive datasets to adapt to a wide range of tasks have attracted considerable attention and are actively being explored within the computer vision community. Among these, the Segment Anything Model…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Hyung-Il Kim , Kimin Yun , Jun-Seok Yun , Yuseok Bae

Medical image processing usually requires a model trained with carefully crafted datasets due to unique image characteristics and domain-specific challenges, especially in pathology. Primitive detection and segmentation in digitized tissue…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Abu Bakor Hayat Arnob , Xiangxue Wang , Yiping Jiao , Xiao Gan , Wenlong Ming , Jun Xu

Purpose: Recent developments in computational pathology have been driven by advances in Vision Foundation Models, particularly the Segment Anything Model (SAM). This model facilitates nuclei segmentation through two primary methods:…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Xueyuan Li , Can Cui , Ruining Deng , Yucheng Tang , Quan Liu , Tianyuan Yao , Shunxing Bao , Naweed Chowdhury , Haichun Yang , Yuankai Huo

Histopathology nuclei segmentation is crucial for quantitative tissue analysis and cancer diagnosis. Although existing segmentation methods have achieved strong performance, they are often computationally heavy and show limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Muhammad Hassan Maqsood , Yanming Zhu , Alfred Lam , Getamesay Dagnaw , Xuefei Yin , Alan Wee-Chung Liew

The Segment Anything Model (SAM) has revolutionized image segmentation through its innovative prompt-based approach, yet the critical role of prompt engineering in its success remains underexplored. This paper presents the first…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Yidong Jiang

The universal model emerges as a promising trend for medical image segmentation, paving up the way to build medical imaging large model (MILM). One popular strategy to build universal models is to encode each task as a one-hot vector and…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Yiwen Ye , Yutong Xie , Jianpeng Zhang , Ziyang Chen , Yong Xia

Medical image segmentation is a crucial and time-consuming task in clinical care, where mask precision is extremely important. The Segment Anything Model (SAM) offers a promising approach, as it provides an interactive interface based on…

Computer Vision and Pattern Recognition · Computer Science 2025-04-30 Julien Khlaut , Elodie Ferreres , Daniel Tordjman , Hélène Philippe , Tom Boeken , Pierre Manceron , Corentin Dancette

Semantic segmentation is a core task in computer vision. Existing methods are generally divided into two categories: automatic and interactive. Interactive approaches, exemplified by the Segment Anything Model (SAM), have shown promise as…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Yimu Pan , Sitao Zhang , Alison D. Gernand , Jeffery A. Goldstein , James Z. Wang

Accurate nuclear instance segmentation is a pivotal task in computational pathology, supporting data-driven clinical insights and facilitating downstream translational applications. While large vision foundation models have shown promise…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Wen Zhang , Qin Ren , Wenjing Liu , Haibin Ling , Chenyu You

Foundation models have shown strong performance in multi-object segmentation with visual prompts, yet histopathology images remain challenging due to high cellular density, heterogeneity, and the gap between pixel-level supervision and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yonghuang Wu , Wenwen Zeng , Xuan Xie , Chengqian Zhao , Guoqing Wu , Jinhua Yu

The Segment Anything Model (SAM) made an eye-catching debut recently and inspired many researchers to explore its potential and limitation in terms of zero-shot generalization capability. As the first promptable foundation model for…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 Dongjie Cheng , Ziyuan Qin , Zekun Jiang , Shaoting Zhang , Qicheng Lao , Kang Li

With the proposal of the Segment Anything Model (SAM), fine-tuning SAM for medical image segmentation (MIS) has become popular. However, due to the large size of the SAM model and the significant domain gap between natural and medical…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Jinfeng Wang , Sifan Song , Xinkun Wang , Yiyi Wang , Yiyi Miao , Jionglong Su , S. Kevin Zhou

Nuclei instance segmentation is critical in computational pathology for cancer diagnosis and prognosis. Recently, the Segment Anything Model has demonstrated exceptional performance in various segmentation tasks, leveraging its rich priors…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Jingze Su , Tianle Zhu , Jiaxin Cai , Zhiyi Wang , Qi Li , Xiao Zhang , Tong Tong , Shu Wang , Wenxi Liu

Segment Anything Models (SAMs) like SEEM and SAM have demonstrated great potential in learning to segment anything. The core design of SAMs lies with Promptable Segmentation, which takes a handcrafted prompt as input and returns the…

Computer Vision and Pattern Recognition · Computer Science 2024-01-10 Jiaxing Huang , Kai Jiang , Jingyi Zhang , Han Qiu , Lewei Lu , Shijian Lu , Eric Xing

The emerging scale segmentation model, Segment Anything (SAM), exhibits impressive capabilities in zero-shot segmentation for natural images. However, when applied to medical images, SAM suffers from noticeable performance drop. To make SAM…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Xinrong Hu , Xiaowei Xu , Yiyu Shi