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There has been devoted significant mathematical research to model the light propagation in tissue and to recover the absorption and scattering coefficients after photoacoustic inversion. Typically, the basic light propagation models…

Mathematical Physics · Physics 2012-07-02 Peter Elbau , Otmar Scherzer

Existing approaches to image reconstruction in photoacoustic computed tomography (PACT) with acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or cannot effectively mitigate the…

Medical Physics · Physics 2013-03-25 Chao Huang , Kun Wang , Liming Nie , Lihong V. Wang , Mark A. Anastasio

Optoacoustic tomography (OAT), also known as photoacoustic tomography, is a rapidly emerging hybrid imaging technique that possesses great potential for a wide range of biomedical imaging applications. In OAT, a laser is employed to…

Medical Physics · Physics 2016-12-21 Yang Lou , Kun Wang , Alexander. A. Oraevsky , Mark. A. Anastasio

Quantitative photoacoustic tomography (qPAT) is an imaging technique aimed at estimating chromophore concentrations inside tissues from photoacoustic images, which are formed by combining optical information and ultrasonic propagation. The…

Computational Physics · Physics 2019-12-23 Hwan Goh , Timo Lahivaara , Tanja Tarvainen , Aki Pulkkinen , Owen Dillon , Ruanui Nicholson , Jari Kaipio

Motion, e.g., due to patient movement or improper device calibration, is inevitable in many imaging modalities such as photoacoustic tomography (PAT) by a rotating system and can lead to undesirable motion artifacts in image…

Numerical Analysis · Mathematics 2016-09-28 Julianne Chung , Linh Nguyen

Quantitative photoacoustic computed tomography (qPACT) is a promising imaging modality for estimating physiological parameters such as blood oxygen saturation. However, developing robust qPACT reconstruction methods remains challenging due…

Medical Physics · Physics 2025-10-07 Refik Mert Cam , Seonyeong Park , Umberto Villa , Mark A. Anastasio

We consider the inverse problem of quantitative reconstruction of properties (e.g., bulk modulus, density) of visco-acoustic materials based on measurements of responding waves after stimulation of the medium. Numerical reconstruction is…

Analysis of PDEs · Mathematics 2022-09-20 Florian Faucher , Otmar Scherzer

Optoacoustic image formation is conventionally based upon ultrasound time-of-flight readings from multiple detection positions. Herein, we exploit acoustic scattering to physically encode the position of optical absorbers in the acquired…

Biological Physics · Physics 2019-10-30 Xose Luis Dean-Ben , Ali Ozbek , Hernan Lopez-Schier , Daniel Razansky

We introduce a mathematical model for ultrasound modulated optical tomography and present a simple reconstruction scheme for recovering the spatially varying optical absorption coefficient from scanning measurements with narrowly focused…

Analysis of PDEs · Mathematics 2010-04-12 Moritz Allmaras , Wolfgang Bangerth

Photoacoustic computed tomography (PACT), also known as optoacoustic tomography, is an emerging imaging modality that has great potential for a wide range of biomedical imaging applications. In this Note, we derive a hybrid reconstruction…

Analysis of PDEs · Mathematics 2015-06-11 Kun Wang , Mark A. Anastasio

We investigate the inverse source problem for the wave equation, arising in photo- and thermoacoustic tomography. There exist quite a few theoretically exact inversion formulas explicitly expressing solution of this problem in terms of the…

Analysis of PDEs · Mathematics 2018-08-01 Ngoc Do , Leonid Kunyansky

Ultrasound attenuation is caused by absorption and scattering in tissue and is thus a function of tissue composition, hence its imaging offers great potential for screening and differential diagnosis. In this paper we propose a novel method…

Signal Processing · Electrical Eng. & Systems 2019-10-15 Richard Rau , Ozan Unal , Dieter Schweizer , Valery Vishnevskiy , Orcun Goksel

The image reconstruction of partially coherent light is interpreted as the quantum state reconstruction. The efficient method based on maximum-likelihood estimation is proposed to acquire information from registered intensity measurements…

Optics · Physics 2011-07-22 M. Jezek , Z. Hradil

Photoacoustic tomography (PAT) is a novel and rapidly promising technique in the field of medical imaging, based on the generation of acoustic waves inside an object of interest by stimulating non-ionizing laser pulses. This acoustic wave…

Analysis of PDEs · Mathematics 2022-02-08 Hyungyeong Jung , Sunghwan Moon

The aim of this paper is to propose for the first time a reconstruction scheme and a stability result for recovering from acoustic-optic data absorption distributions with bounded variation. The paper extends earlier results on smooth…

Analysis of PDEs · Mathematics 2014-05-13 Habib Ammari , Loc Hoang Nguyen , Laurent Seppecher

In deep tissue photoacoustic imaging the spatial resolution is inherently limited by the acoustic wavelength. Recently, it was demonstrated that it is possible to surpass the acoustic diffraction limit by analyzing fluctuations in a set of…

The aim of this paper is to put the problem of vibroacoustic imaging into the mathematical framework of inverse problems (more precisely, coefficient identification in PDEs) and regularization. We present a model in frequency domain, prove…

Analysis of PDEs · Mathematics 2021-09-07 Barbara Kaltenbacher

Photoacoustic tomography (PAT) has the potential to recover morphological and functional tissue properties with high spatial resolution. However, previous attempts to solve the optical inverse problem with supervised machine learning were…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Melanie Schellenberg , Janek Gröhl , Kris K. Dreher , Jan-Hinrich Nölke , Niklas Holzwarth , Minu D. Tizabi , Alexander Seitel , Lena Maier-Hein

Acoustic-resolution optoacoustic microscopy (AR-OAM) retrieves anatomical and functional contrast from living tissues at depths not reachable with optical microscopy. The imaging performance of AR-OAM has been advanced with image…

We consider the problem of signal reconstruction for computed tomography (CT) under a nonlinear forward model that accounts for exponential signal attenuation, a polychromatic X-ray source, general measurement noise (e.g., Poisson shot…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Mengqi Lou , Kabir Aladin Verchand , Sara Fridovich-Keil , Ashwin Pananjady