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Understanding the spatial architecture of the tumor microenvironment (TME) is critical to advance precision oncology. We present ProteinPNet, a novel framework based on prototypical part networks that discovers TME motifs from spatial…

Machine Learning · Computer Science 2025-12-03 Louis McConnell , Jieran Sun , Theo Maffei , Raphael Gottardo , Marianna Rapsomaniki

As artificial intelligence increasingly drives critical decisions, the ability to genuinely explain how neural networks make predictions is essential for trust. Yet, most current explanation methods offer post-hoc rationalizations rather…

Machine Learning · Computer Science 2026-05-08 Corentin Lobet , Francesca Chiaromonte

Interpretable part-prototype models are computer vision models that are explainable by design. The models learn prototypical parts and recognise these components in an image, thereby combining classification and explanation. Despite the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-28 Meike Nauta , Christin Seifert

We introduce ProtoPool, an interpretable image classification model with a pool of prototypes shared by the classes. The training is more straightforward than in the existing methods because it does not require the pruning stage. It is…

Computer Vision and Pattern Recognition · Computer Science 2022-09-07 Dawid Rymarczyk , Łukasz Struski , Michał Górszczak , Koryna Lewandowska , Jacek Tabor , Bartosz Zieliński

In recent years there has been a considerable amount of research on local post hoc explanations for neural networks. However, work on building interpretable neural architectures has been relatively sparse. In this paper, we present a novel…

Machine Learning · Computer Science 2025-06-09 Isha Puri , Amit Dhurandhar , Tejaswini Pedapati , Kartikeyan Shanmugam , Dennis Wei , Kush R. Varshney

Interpretable deep learning models have received widespread attention in the field of image recognition. Due to the unique multi-instance learning of medical images and the difficulty in identifying decision-making regions, many…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Yitao Peng , Lianghua He , Die Hu , Yihang Liu , Longzhen Yang , Shaohua Shang

Part-prototype networks have recently become methods of interest as an interpretable alternative to many of the current black-box image classifiers. However, the interpretability of these methods from the perspective of human users has not…

Computer Vision and Pattern Recognition · Computer Science 2024-01-08 Omid Davoodi , Shayan Mohammadizadehsamakosh , Majid Komeili

Balancing predictive power and interpretability has long been a challenging research area, particularly in powerful yet complex models like neural networks, where nonlinearity obstructs direct interpretation. This paper introduces a novel…

Machine Learning · Computer Science 2025-02-20 Antoine Ledent , Peng Liu

Collaborative reasoning for understanding image-question pairs is a very critical but underexplored topic in interpretable visual question answering systems. Although very recent studies have attempted to use explicit compositional…

Computer Vision and Pattern Recognition · Computer Science 2019-12-30 Qingxing Cao , Bailin Li , Xiaodan Liang , Liang Lin

Interpretability is crucial for machine learning algorithms in high-stakes medical applications. However, high-performing neural networks typically cannot explain their predictions. Post-hoc explanation methods provide a way to understand…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Susu Sun , Stefano Woerner , Andreas Maier , Lisa M. Koch , Christian F. Baumgartner

This paper has proposed a new baseline deep learning model of more benefits for image classification. Different from the convolutional neural network(CNN) practice where filters are trained by back propagation to represent different…

Computer Vision and Pattern Recognition · Computer Science 2021-08-13 Yifei Li , Kuangyan Song , Yiming Sun , Liao Zhu

The adoption of Deep Learning algorithms in the medical imaging field is a prominent area of research, with high potential for advancing AI-based Computer-aided diagnosis (AI-CAD) solutions. However, current solutions face challenges due to…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Iury B. de A. Santos , André C. P. L. F. de Carvalho

Continual learning constrains models to learn new tasks over time without forgetting what they have already learned. A key challenge in this setting is catastrophic forgetting, where learning new information causes the model to lose its…

Machine Learning · Computer Science 2025-12-10 Federico Di Valerio , Michela Proietti , Alessio Ragno , Roberto Capobianco

State of the art algorithms for many pattern recognition problems rely on deep network models. Training these models requires a large labeled dataset and considerable computational resources. Also, it is difficult to understand the working…

Artificial Intelligence · Computer Science 2019-09-25 Heather Riley , Mohan Sridharan

Semantic image interpretation can vastly benefit from approaches that combine sub-symbolic distributed representation learning with the capability to reason at a higher level of abstraction. Logic Tensor Networks (LTNs) are a class of…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Simone Martone , Francesco Manigrasso , Lamberti Fabrizio , Lia Morra

Prototypical parts-based networks are becoming increasingly popular due to their faithful self-explanations. However, their similarity maps are calculated in the penultimate network layer. Therefore, the receptive field of the prototype…

Computer Vision and Pattern Recognition · Computer Science 2023-08-17 Mikołaj Sacha , Bartosz Jura , Dawid Rymarczyk , Łukasz Struski , Jacek Tabor , Bartosz Zieliński

Convolutional neural networks (CNNs) have shown exceptional performance for a range of medical imaging tasks. However, conventional CNNs are not able to explain their reasoning process, therefore limiting their adoption in clinical…

Computer Vision and Pattern Recognition · Computer Science 2022-08-02 Linde S. Hesse , Ana I. L. Namburete

Automated diagnosis with artificial intelligence has emerged as a promising area in the realm of medical imaging, while the interpretability of the introduced deep neural networks still remains an urgent concern. Although contemporary…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Binghua Li , Jie Mao , Zhe Sun , Chao Li , Qibin Zhao , Toshihisa Tanaka

Pretrained transformer-based Language Models (LMs) are well-known for their ability to achieve significant improvement on text classification tasks with their powerful word embeddings, but their black-box nature, which leads to a lack of…

Computation and Language · Computer Science 2024-12-23 Ximing Wen , Wenjuan Tan , Rosina O. Weber

We propose an efficient Stereographic Projection Neural Network (SPNet) for learning representations of 3D objects. We first transform a 3D input volume into a 2D planar image using stereographic projection. We then present a shallow 2D…

Computer Vision and Pattern Recognition · Computer Science 2019-01-25 Mohsen Yavartanoo , Eu Young Kim , Kyoung Mu Lee