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Diabetic Retinopathy (DR) is among the worlds leading vision loss causes in diabetic patients. DR is a microvascular disease that affects the eye retina, which causes vessel blockage and therefore cuts the main source of nutrition for the…

Image and Video Processing · Electrical Eng. & Systems 2021-06-24 Israa Odeh , Mouhammd Alkasassbeh , Mohammad Alauthman

Diabetic retinopathy (DR) and diabetic macular edema (DME) are the leading causes of permanent blindness in the working-age population. Automatic grading of DR and DME helps ophthalmologists design tailored treatments to patients, thus is…

Image and Video Processing · Electrical Eng. & Systems 2019-11-05 Xiaomeng Li , Xiaowei Hu , Lequan Yu , Lei Zhu , Chi-Wing Fu , Pheng-Ann Heng

This article aims to classify diabetic retinopathy (DR) disease into five different classes using an ensemble approach based on two popular pre-trained convolutional neural networks: VGG16 and Inception V3. The proposed model aims to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-02 Susmita Ghosh , Abhiroop Chatterjee

Noisy data and the similarity in the ocular appearances caused by different ophthalmic pathologies pose significant challenges for an automated expert system to accurately detect retinal diseases. In addition, the lack of knowledge…

Image and Video Processing · Electrical Eng. & Systems 2021-10-20 Sharif Amit Kamran , Alireza Tavakkoli , Stewart Lee Zuckerbrod

Purpose: As visual inspection is an inherent process during radiological screening, the associated eye gaze data can provide valuable insights into relevant clinical decisions. As deep learning has become the state-of-the-art for…

Image and Video Processing · Electrical Eng. & Systems 2025-02-18 Zirui Qiu , Hassan Rivaz , Yiming Xiao

Retinal optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) are promising tools for the (early) diagnosis of Alzheimer's disease (AD). These non-invasive imaging techniques are cost-effective and more…

Image and Video Processing · Electrical Eng. & Systems 2022-09-09 Yasemin Turkan , F. Boray Tek

Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Aniket Joshi , Gaurav Mishra , Jayanthi Sivaswamy

Automatic classification of Diabetic Retinopathy (DR) can assist ophthalmologists in devising personalized treatment plans, making it a critical component of clinical practice. However, imbalanced data distribution in the dataset becomes a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Abdul Hannan , Zahid Mahmood , Rizwan Qureshi , Hazrat Ali

Objective: Optical coherence tomography (OCT) and its angiography (OCTA) have several advantages for the early detection and diagnosis of diabetic retinopathy (DR). However, automated, complete DR classification frameworks based on both OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-09-28 Pengxiao Zang , Liqin Gao , Tristan T. Hormel , Jie Wang , Qisheng You , Thomas S. Hwang , Yali Jia

Objective: Diabetic macular edema (DME) is the leading cause of severe visual impairment in patients with diabetes. Quantification of retinal fluid, particularly intraretinal fluid (IRF) and subretinal fluid (SRF), plays a critical role in…

Image and Video Processing · Electrical Eng. & Systems 2026-04-27 Zijun Lei , Zikang Xu , Liang Zhang , Ge Song , Hanyu Guo , Dan Cao , Yujia Zhou , Qianjin Feng

We describe a new approach to automated Glaucoma detection in 3D Spectral Domain Optical Coherence Tomography (OCT) optic nerve scans. First, we gathered a unique and diverse multi-ethnic dataset of OCT scans consisting of glaucoma and…

Age-related Macular Degeneration (AMD) and Diabetic Macular Edema (DME) are the major causes of vision loss in developed countries. Alteration of retinal layer structure and appearance of exudate are the most significant signs of these…

Image and Video Processing · Electrical Eng. & Systems 2019-03-19 Elahe Mousavi , Rahele Kafieh , Hossein Rabbani

Early identification of patients at risk of cardiovascular diseases (CVD) is crucial for effective preventive care, reducing healthcare burden, and improving patients' quality of life. This study demonstrates the potential of retinal…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Cynthia Maldonado-Garcia , Arezoo Zakeri , Alejandro F Frangi , Nishant Ravikumar

Optical coherence tomography (OCT) based measurements of retinal layer thickness, such as the retinal nerve fibre layer (RNFL) and the ganglion cell with inner plexiform layer (GCIPL) are commonly used for the diagnosis and monitoring of…

Computer Vision and Pattern Recognition · Computer Science 2019-10-25 Stefan Maetschke , Bhavna Antony , Hiroshi Ishikawa , Gadi Wollstein , Joel S. Schuman , Rahil Garnavi

Automatic clinical diagnosis of retinal diseases has emerged as a promising approach to facilitate discovery in areas with limited access to specialists. We propose a novel visual-assisted diagnosis hybrid model based on the support vector…

Computer Vision and Pattern Recognition · Computer Science 2018-07-05 C. -H. Huck Yang , Jia-Hong Huang , Fangyu Liu , Fang-Yi Chiu , Mengya Gao , Weifeng Lyu , I-Hung Lin M. D. , Jesper Tegner

The treatment of age-related macular degeneration (AMD) requires continuous eye exams using optical coherence tomography (OCT). The need for treatment is determined by the presence or change of disease-specific OCT-based biomarkers.…

Image and Video Processing · Electrical Eng. & Systems 2026-03-12 Timo Kepp , Helge Sudkamp , Claus von der Burchard , Hendrik Schenke , Peter Koch , Gereon Hüttmann , Johann Roider , Mattias P. Heinrich , Heinz Handels

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects cognitive functions such as memory, thinking, and behavior. In this disease, there is a critical phase, mild cognitive impairment, that is really…

Signal Processing · Electrical Eng. & Systems 2024-04-02 Arezoo Borji , Taha-Hossein Hejazi , Abbas Seifi

This research paper addresses the critical challenge of diabetic retinopathy (DR), a severe complication of diabetes leading to potential blindness. The proposed methodology leverages transfer learning with convolutional neural networks…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Manoj S H , Arya A Bosale

Retinopathy represents a group of retinal diseases that, if not treated timely, can cause severe visual impairments or even blindness. Many researchers have developed autonomous systems to recognize retinopathy via fundus and optical…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Taimur Hassan , Bilal Hassan , Muhammad Usman Akram , Shahrukh Hashmi , Abdel Hakim Taguri , Naoufel Werghi

Automatic clinical diagnosis of retinal diseases has emerged as a promising approach to facilitate discovery in areas with limited access to specialists. Based on the fact that fundus structure and vascular disorders are the main…

Computer Vision and Pattern Recognition · Computer Science 2018-11-05 C. -H. Huck Yang , Fangyu Liu , Jia-Hong Huang , Meng Tian , Hiromasa Morikawa , I-Hung Lin , Yi-Chieh Liu , Hao-Hsiang Yang , Jesper Tegner