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Machine learning (ML) holds great promise for clinical applications but is often hindered by limited access to high-quality data due to privacy concerns, high costs, and long timelines associated with clinical trials. While large language…

Computation and Language · Computer Science 2026-03-27 Zerui Xu , Fang Wu , Yingzhou Lu , Yuanyuan Zhang , Yue Zhao

This paper presents a solver-friendly logic-based mixed-integer nonlinear programming model (LB-MINLP) to solve economic dispatch (ED) problems considering disjoint operating zones and valve-point effects. A simultaneous consideration of…

Optimization and Control · Mathematics 2018-10-15 Mahdi Pourakbari-Kasmaei , Mahmud Fotuhi-Firuzabad , Jose Roberto Sanches Mantovani

As multiple crises threaten the sustainability of our societies and pose at risk the planetary boundaries, complex challenges require timely, updated, and usable information. Natural-language processing (NLP) tools enhance and expand data…

Computers and Society · Computer Science 2025-02-05 Francesca Larosa , Sergio Hoyas , H. Alberto Conejero , Javier Garcia-Martinez , Francesco Fuso Nerini , Ricardo Vinuesa

Recent advancements in large language models (LLMs) have spurred interest in robotic navigation that incorporates complex spatial, mathematical, and conditional constraints from natural language into the planning problem. Such constraints…

Artificial Intelligence · Computer Science 2026-04-10 Amin Seffo , Aladin Djuhera , Masataro Asai , Holger Boche

Recently, Large Language Models (LLMs) have showcased their potential in various natural language processing tasks, including code generation. However, while significant progress has been made in adapting LLMs to generate code for several…

Machine Learning · Computer Science 2024-07-29 Erica Coppolillo , Francesco Calimeri , Giuseppe Manco , Simona Perri , Francesco Ricca

We establish a broad methodological foundation for mixed-integer optimization with learned constraints. We propose an end-to-end pipeline for data-driven decision making in which constraints and objectives are directly learned from data…

Optimization and Control · Mathematics 2023-10-30 Donato Maragno , Holly Wiberg , Dimitris Bertsimas , S. Ilker Birbil , Dick den Hertog , Adejuyigbe Fajemisin

Enhancing the mathematical reasoning of large language models (LLMs) demands high-quality training data, yet conventional methods face critical challenges in scalability, cost, and data reliability. To address these limitations, we propose…

Computation and Language · Computer Science 2025-08-27 Sirui Chen , Changxin Tian , Binbin Hu , Kunlong Chen , Ziqi Liu , Zhiqiang Zhang , Jun Zhou

Autonomous systems must solve motion planning problems subject to increasingly complex, time-sensitive, and uncertain missions. These problems often involve high-level task specifications, such as temporal logic or chance constraints, which…

Systems and Control · Electrical Eng. & Systems 2026-04-28 Junyang Cai , Weimin Huang , Brendan Long , Matthew Cleaveland , Jyotirmoy V. Deshmukh , Lars Lindemann , Bistra Dilkina

Large language models (LLMs) have substantially advanced machine learning research, including natural language processing, computer vision, data mining, etc., yet they still exhibit critical limitations in explainability, reliability,…

Machine Learning · Computer Science 2025-09-19 Xin Wang , Haoyang Li , Haibo Chen , Zeyang Zhang , Wenwu Zhu

Mixed Integer Linear Programming (MILP) is a fundamental class of NP-hard problems that has garnered significant attention from both academia and industry. The Branch-and-Bound (B\&B) method is the dominant approach for solving MILPs and…

Machine Learning · Computer Science 2025-11-27 Tongkai Lu , Shuai Ma , Chongyang Tao

Large Language Models (LLMs) have significantly advanced artificial intelligence by optimizing traditional Natural Language Processing (NLP) workflows, facilitating their integration into various systems. Many such NLP systems, including…

Computation and Language · Computer Science 2025-05-13 Jiliang Ni , Jiachen Pu , Zhongyi Yang , Kun Zhou , Hui Wang , Xiaoliang Xiao , Dakui Wang , Xin Li , Jingfeng Luo , Conggang Hu

In this paper, we propose two exact distributed algorithms to solve mixed integer linear programming (MILP) problems with multiple agents where data privacy is important for the agents. A key challenge is that, because of the non-convex…

Optimization and Control · Mathematics 2022-05-03 Mohammad Javad Feizollahi

Large Language Models (LLMs) have recently demonstrated impressive capabilities across various real-world applications. However, due to the current text-in-text-out paradigm, it remains challenging for LLMs to handle dynamic and complex…

Artificial Intelligence · Computer Science 2024-10-25 Timothy Wei , Annabelle Miin , Anastasia Miin

We address the optimal design of a large scale multi-agent system where each agent has discrete and/or continuous decision variables that need to be set so as to optimize the sum of linear local cost functions, in presence of linear local…

Optimization and Control · Mathematics 2017-06-28 Alessandro Falsone , Kostas Margellos , Maria Prandini

Dynamic programming (DP) is a fundamental method in operations research, but formulating DP models has traditionally required expert knowledge of both the problem context and DP techniques. Large Language Models (LLMs) offer the potential…

Artificial Intelligence · Computer Science 2026-04-02 Chenyu Zhou , Jingyuan Yang , Linwei Xin , Yitian Chen , Ziyan He , Dongdong Ge

Large language models (LLMs) enable system builders today to create competent NLP systems through prompting, where they only need to describe the task in natural language and provide a few examples. However, in other ways, LLMs are a step…

Computation and Language · Computer Science 2023-08-24 Vijay Viswanathan , Chenyang Zhao , Amanda Bertsch , Tongshuang Wu , Graham Neubig

We address the solution of Mixed Integer Linear Programming (MILP) models with strong relaxations that are derived from Dantzig-Wolfe decompositions and allow a pseudo-polynomial pricing algorithm. We exploit their network-flow…

Optimization and Control · Mathematics 2021-06-01 Vinícius L. de Lima , Manuel Iori , Flávio K. Miyazawa

Machine learning interatomic potentials (MLIPs) have become powerful tools to extend molecular simulations beyond the limits of quantum methods, offering near-quantum accuracy at much lower computational cost. Yet, developing reliable MLIPs…

Materials Science · Physics 2025-12-30 Adam Lahouari , Jutta Rogal , Mark E. Tuckerman

Mixed-Integer Linear Programming (MILP) is widely used in fields such as scheduling, logistics, and planning. Enhancing the performance of MILP solvers, particularly learning-based solvers, requires substantial amounts of high-quality data.…

Optimization and Control · Mathematics 2025-05-20 Tianxing Yang , Huigen Ye , Hua Xu

Mixed-integer programming (MIP) research is both mathematically sophisticated and engineering-intensive: testing an algorithmic hypothesis within a branch-and-cut solver requires substantial implementation, debugging, tuning, and…

Artificial Intelligence · Computer Science 2026-05-12 Liding Xu , Yugeng Zhou , Sebastian Pokutta