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Automated dermoscopic image analysis has witnessed rapid growth in diagnostic performance. Yet adoption faces resistance, in part, because no evidence is provided to support decisions. In this work, an approach for evidence-based…

Computer Vision and Pattern Recognition · Computer Science 2018-08-03 Noel C. F. Codella , Chung-Ching Lin , Allan Halpern , Michael Hind , Rogerio Feris , John R. Smith

Deep learning has achieved significant breakthroughs in medical imaging, but these advancements are often dependent on large, well-annotated datasets. However, obtaining such datasets poses a significant challenge, as it requires…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Siteng Ma , Honghui Du , Yu An , Jing Wang , Qinqin Wang , Haochang Wu , Aonghus Lawlor , Ruihai Dong

Microtubule networks (MTs) are a component of a cell that may indicate the presence of various chemical compounds and can be used to recognize properties such as treatment resistance. Therefore, the classification of MT images is of great…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 Aleksei Shpilman , Dmitry Boikiy , Marina Polyakova , Daniel Kudenko , Anton Burakov , Elena Nadezhdina

We propose a new deep learning approach for medical imaging that copes with the problem of a small training set, the main bottleneck of deep learning, and apply it for classification of healthy and cancer cells acquired by quantitative…

Image and Video Processing · Electrical Eng. & Systems 2018-12-31 Moran Rubin , Omer Stein , Nir A. Turko , Yoav Nygate , Darina Roitshtain , Lidor Karako , Itay Barnea , Raja Giryes , Natan T. Shaked

Medical image classification is crucial for diagnosis and treatment, benefiting significantly from advancements in artificial intelligence. The paper reviews recent progress in the field, focusing on three levels of solutions: basic,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-06 Loan Dao , Ngoc Quoc Ly

Recently, deep learning-based methods achieved promising performance in nuclei detection and classification applications. However, training deep learning-based methods requires a large amount of pixel-wise annotated data, which is…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Nazanin Moradinasab , Rebecca A. Deaton , Laura S. Shankman , Gary K. Owens , Donald E. Brown

Diagnosing diseases such as leukemia or anemia requires reliable counts of blood cells. Hematologists usually label and count microscopy images of blood cells manually. In many cases, however, cells in different maturity states are…

Machine Learning · Computer Science 2020-07-13 Yushan Liu , Markus M. Geipel , Christoph Tietz , Florian Buettner

While deep learning strategies achieve outstanding results in computer vision tasks, one issue remains: The current strategies rely heavily on a huge amount of labeled data. In many real-world problems, it is not feasible to create such an…

Computer Vision and Pattern Recognition · Computer Science 2021-10-14 Lars Schmarje , Monty Santarossa , Simon-Martin Schröder , Reinhard Koch

Automated and semi-automated techniques in biomedical electron microscopy (EM) enable the acquisition of large datasets at a high rate. Segmentation methods are therefore essential to analyze and interpret these large volumes of data, which…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Anusha Aswath , Ahmad Alsahaf , Ben N. G. Giepmans , George Azzopardi

Classification of HEp-2 cell patterns plays a significant role in the indirect immunofluorescence test for identifying autoimmune diseases in the human body. Many automatic HEp-2 cell classification methods have been proposed in recent…

Computer Vision and Pattern Recognition · Computer Science 2020-08-07 Saimunur Rahman , Lei Wang , Changming Sun , Luping Zhou

Deep learning is the current bet for image classification. Its greed for huge amounts of annotated data limits its usage in medical imaging context. In this scenario transfer learning appears as a prominent solution. In this report we aim…

Computer Vision and Pattern Recognition · Computer Science 2016-09-06 Afonso Menegola , Michel Fornaciali , Ramon Pires , Sandra Avila , Eduardo Valle

Deep Learning has shown outstanding results in computer vision tasks; healthcare is no exception. However, there is no straightforward way to expose the decision-making process of DL models. Good accuracy is not enough for skin cancer…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Rosa Y. G. Paccotacya-Yanque , Alceu Bissoto , Sandra Avila

Recent evolution in deep learning has proven its value for CT-based lung nodule classification. Most current techniques are intrinsically black-box systems, suffering from two generalizability issues in clinical practice. First,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-28 Hanxiao Zhang , Liang Chen , Xiao Gu , Minghui Zhang , Yulei Qin , Feng Yao , Zhexin Wang , Yun Gu , Guang-Zhong Yang

Intraoperative visualization of hemodynamics is crucial for accurate diagnosis and informed surgical decision-making. In neurosurgery, indocyanine green fluorescence imaging (ICG-FI) is the gold standard for assessing blood flow and…

Medical Physics · Physics 2025-10-20 Yan Shi , Denghui Zhao , Jingyi Yu , Wei Ni , Pengcheng Li , Yun Gu , Peng Miao , Shanbao Tong

How can we find interpretable, domain-appropriate models of natural phenomena given some complex, raw data such as images? Can we use such models to derive scientific insight from the data? In this paper, we propose some methods for…

Machine Learning · Computer Science 2024-02-06 Christopher J. Soelistyo , Alan R. Lowe

Deep learning has significantly advanced medical imaging analysis (MIA), achieving state-of-the-art performance across diverse clinical tasks. However, its success largely depends on large-scale, high-quality labeled datasets, which are…

Computer Vision and Pattern Recognition · Computer Science 2025-05-09 Cheng Jin , Zhengrui Guo , Yi Lin , Luyang Luo , Hao Chen

The increasing availability of biomedical data is helping to design more robust deep learning (DL) algorithms to analyze biomedical samples. Currently, one of the main limitations to train DL algorithms to perform a specific task is the…

Medical image classification is a critical problem for healthcare, with the potential to alleviate the workload of doctors and facilitate diagnoses of patients. However, two challenges arise when deploying deep learning models to real-world…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 An Yan , Yu Wang , Yiwu Zhong , Zexue He , Petros Karypis , Zihan Wang , Chengyu Dong , Amilcare Gentili , Chun-Nan Hsu , Jingbo Shang , Julian McAuley

Detection and differentiation of circulating tumor cells (CTCs) and non-CTCs in blood draws of cancer patients pose multiple challenges. While the gold standard relies on tedious manual evaluation of an automatically generated selection of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Hümeyra Husseini-Wüsthoff , Sabine Riethdorf , Andreas Schneeweiss , Andreas Trumpp , Klaus Pantel , Harriet Wikman , Maximilian Nielsen , René Werner

Convolutional Neural Networks (CNNs) have proven to be state-of-the-art models for supervised computer vision tasks, such as image classification. However, large labeled data sets are generally needed for the training and validation of such…

Machine Learning · Computer Science 2020-10-28 Patrick Hemmer , Niklas Kühl , Jakob Schöffer