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Magnetic resonance imaging (MRI) is a powerful medical imaging modality, but long acquisition times limit throughput, patient comfort, and clinical accessibility. Diffusion-based generative models serve as strong image priors for reducing…

Machine Learning · Computer Science 2026-02-13 Sriram Ravula , Brett Levac , Yamin Arefeen , Ajil Jalal , Alexandros G. Dimakis , Jonathan I. Tamir

The integration of positron emission tomography (PET) and magnetic resonance imaging (MRI) has been an ongoing research topic for the last 20 years. This paper gives an overview of the different developments and the technical problems…

Medical Physics · Physics 2015-10-19 Stefaan Vandenberghe , Paul Marsden

Magnetic Resonance Imaging (MRI), including diffusion MRI (dMRI), serves as a ``microscope'' for anatomical structures and routinely mitigates the influence of low signal-to-noise ratio scans by compromising temporal or spatial resolution.…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Chenxu Wu , Qingpeng Kong , Zihang Jiang , S. Kevin Zhou

Diffusion models have emerged as a leading methodology for image generation and have proven successful in the realm of magnetic resonance imaging (MRI) reconstruction. However, existing reconstruction methods based on diffusion models are…

Computer Vision and Pattern Recognition · Computer Science 2024-04-23 Zhuo-Xu Cui , Chentao Cao , Yue Wang , Sen Jia , Jing Cheng , Xin Liu , Hairong Zheng , Dong Liang , Yanjie Zhu

Low-dose Positron Emission Tomography (PET) reduces radiation exposure but suffers from severe noise and quantitative degradation. Diffusion-based denoising models achieve strong final reconstructions, yet their reverse trajectories are…

Image-generative artificial intelligence (AI) has garnered significant attention in recent years. In particular, the diffusion model, a core component of generative AI, produces high-quality images with rich diversity. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Sho Ozaki , Shizuo Kaji , Toshikazu Imae , Kanabu Nawa , Hideomi Yamashita , Keiichi Nakagawa

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Huidong Xie , Weijie Gan , Bo Zhou , Xiongchao Chen , Qiong Liu , Xueqi Guo , Liang Guo , Hongyu An , Ulugbek S. Kamilov , Ge Wang , Chi Liu

This study introduces a novel approach for image reconstruction based on a diffusion model conditioned on the native data domain. Our method is applied to multi-coil MRI and quantitative MRI reconstruction, leveraging the domain-conditioned…

Machine Learning · Computer Science 2023-09-06 Wanyu Bian , Albert Jang , Fang Liu

Image quality of PET reconstructions is degraded by subject motion occurring during the acquisition. MR-based motion correction approaches have been studied for PET/MR scanners and have been successful at capturing regular motion patterns,…

Multimodal image fusion aims to combine relevant information from images acquired with different sensors. In medical imaging, fused images play an essential role in both standard and automated diagnosis. In this paper, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2021-02-18 Farshad G. Veshki , Nora Ouzir , Sergiy A. Vorobyov , Esa Ollila

Generating multi-contrasts/modal MRI of the same anatomy enriches diagnostic information but is limited in practice due to excessive data acquisition time. In this paper, we propose a novel deep-learning model for joint reconstruction and…

Image and Video Processing · Electrical Eng. & Systems 2022-06-30 Wanyu Bian , Qingchao Zhang , Xiaojing Ye , Yunmei Chen

Magnetic resonance imaging (MRI) is a vital diagnostic tool, but its inherently long acquisition times reduce clinical efficiency and patient comfort. Recent advancements in deep learning, particularly diffusion models, have improved…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Yuxuan Zhang , Jinkui Hao , Bo Zhou

Reconstruction of PET images is an ill-posed inverse problem and often requires iterative algorithms to achieve good image quality for reliable clinical use in practice, at huge computational costs. In this paper, we consider the PET…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Jieqing Jiao , Sebastien Ourselin

Positron Emission Tomography (PET) image reconstruction is inherently challenged by Poisson noise and physical degradation factors, which are further exacerbated in limited-angle acquisitions. While deep learning methods demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Rüveyda Yilmaz , Yuli Wu , Johannes Stegmaier , Volkmar Schulz

Alzheimer's disease (AD) is the most prevalent form of dementia, and its early diagnosis is essential for slowing disease progression. Recent studies on multimodal neuroimaging fusion using MRI and PET have achieved promising results by…

Computer Vision and Pattern Recognition · Computer Science 2025-11-05 Delin Ma , Menghui Zhou , Jun Qi , Yun Yang , Po Yang

The rapid advancement of Artificial Intelligence (AI) in biomedical imaging and radiotherapy is hindered by the limited availability of large imaging data repositories. With recent research and improvements in denoising diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Rowan Bradbury , Katherine A. Vallis , Bartlomiej W. Papiez

Computed Tomography (CT) technology reduces radiation haz-ards to the human body through sparse sampling, but fewer sampling angles pose challenges for image reconstruction. Score-based generative models are widely used in sparse-view CT…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Junyan Zhang , Mengxiao Geng , Pinhuang Tan , Yi Liu , Zhili Liu , Bin Huang , Qiegen Liu

Diffusion model has been successfully applied to MRI reconstruction, including single and multi-coil acquisition of MRI data. Simultaneous multi-slice imaging (SMS), as a method for accelerating MR acquisition, can significantly reduce…

Image and Video Processing · Electrical Eng. & Systems 2024-08-22 Ting Zhao , Zhuoxu Cui , Sen Jia , Qingyong Zhu , Congcong Liu , Yihang Zhou , Yanjie Zhu , Dong Liang , Haifeng Wang

Recent advances in diffusion models have demonstrated exceptional performance in generative tasks across vari-ous fields. In positron emission tomography (PET), the reduction in tracer dose leads to information loss in sino-grams. Using…

Machine Learning · Computer Science 2024-11-11 Xingyu Ai , Bin Huang , Fang Chen , Liu Shi , Binxuan Li , Shaoyu Wang , Qiegen Liu

Multi-center positron emission tomography (PET) image synthesis aims at recovering low-dose PET images from multiple different centers. The generalizability of existing methods can still be suboptimal for a multi-center study due to domain…

Image and Video Processing · Electrical Eng. & Systems 2023-07-12 Zhiwen Yang , Yang Zhou , Hui Zhang , Bingzheng Wei , Yubo Fan , Yan Xu