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Many ML models are opaque to humans, producing decisions too complex for humans to easily understand. In response, explainable artificial intelligence (XAI) tools that analyze the inner workings of a model have been created. Despite these…

Computers and Society · Computer Science 2021-06-17 Kiana Alikhademi , Brianna Richardson , Emma Drobina , Juan E. Gilbert

Although machine learning (ML) models of AI achieve high performances in medicine, they are not free of errors. Empowering clinicians to identify incorrect model recommendations is crucial for engendering trust in medical AI. Explainable AI…

Artificial Intelligence · Computer Science 2022-12-20 Isil Guzey , Ozlem Ucar , Nukhet Aladag Ciftdemir , Betul Acunas

The opaque nature of deep learning models remains a significant barrier to their clinical adoption in medical imaging. This paper presents a multimodal explainability framework that bridges the gap between convolutional neural network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Paul Valery Nguezet , Elie Tagne Fute , Yusuf Brima , Benoit Martin Azanguezet , Marcellin Atemkeng

Explainability is critical for deep learning applications in healthcare which are mandated to provide interpretations to both patients and doctors according to legal regulations and responsibilities. Explainable AI methods, such as feature…

Image and Video Processing · Electrical Eng. & Systems 2023-11-01 Jinze Zhao

Modern AI systems frequently rely on opaque black-box models, most notably Deep Neural Networks, whose performance stems from complex architectures with millions of learned parameters. While powerful, their complexity poses a major…

Machine Learning · Computer Science 2026-02-23 David Dembinsky , Adriano Lucieri , Stanislav Frolov , Hiba Najjar , Ko Watanabe , Andreas Dengel

The increasing complexity of Artificial Intelligence models poses challenges to interpretability, particularly in the healthcare sector. This study investigates the impact of deep learning model complexity and Explainable AI (XAI) efficacy,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Mateusz Cedro , Marcin Chlebus

A main drawback of eXplainable Artificial Intelligence (XAI) approaches is the feature independence assumption, hindering the study of potential variable dependencies. This leads to approximating black box behaviors by analyzing the effects…

Artificial Intelligence · Computer Science 2024-10-16 Martina Cinquini , Riccardo Guidotti

Artificial Intelligence in Medicine has made significant progress with emerging applications in medical imaging, patient care, and other areas. While these applications have proven successful in retrospective studies, very few of them were…

Artificial Intelligence · Computer Science 2023-08-11 Nicoletta Prentzas , Antonis Kakas , Constantinos S. Pattichis

Deep learning models show significant potential for advancing AI-assisted medical diagnostics, particularly in detecting lung cancer through medical image modalities such as chest X-rays. However, the black-box nature of these models poses…

Machine Learning · Computer Science 2025-03-31 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

Artificial intelligence models encounter significant challenges due to their black-box nature, particularly in safety-critical domains such as healthcare, finance, and autonomous vehicles. Explainable Artificial Intelligence (XAI) addresses…

Artificial Intelligence · Computer Science 2025-03-14 Melkamu Mersha , Khang Lam , Joseph Wood , Ali AlShami , Jugal Kalita

Explainability is a key requirement for computer-aided diagnosis systems in clinical decision-making. Multiple instance learning with attention pooling provides instance-level explainability, however for many clinical applications a deeper,…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Ario Sadafi , Oleksandra Adonkina , Ashkan Khakzar , Peter Lienemann , Rudolf Matthias Hehr , Daniel Rueckert , Nassir Navab , Carsten Marr

Deep learning models have achieved remarkable success across diverse domains. However, the intricate nature of these models often impedes a clear understanding of their decision-making processes. This is where Explainable AI (XAI) becomes…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Soham Mitra , Atri Sukul , Swalpa Kumar Roy , Pravendra Singh , Vinay Verma

While deep learning has exhibited remarkable predictive capabilities in various medical image tasks, its inherent black-box nature has hindered its widespread implementation in real-world healthcare settings. Our objective is to unveil the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Han Yuan , Lican Kang , Yong Li

This study deliberates on the application of advanced AI techniques for brain tumor classification through MRI, wherein the training includes the present best deep learning models to enhance diagnosis accuracy and the potential of usability…

Recent advancement in machine learning algorithms reaches a point where medical devices can be equipped with artificial intelligence (AI) models for diagnostic support and routine automation in clinical settings. In medicine and healthcare,…

Machine Learning · Statistics 2025-02-21 Takeshi Abe , Yoshiyuki Asai

Developing and certifying safe - or so-called trustworthy - AI has become an increasingly salient issue, especially in light of upcoming regulation such as the EU AI Act. In this context, the black-box nature of machine learning models…

The integration of artificial intelligence into business processes has significantly enhanced decision-making capabilities across various industries such as finance, healthcare, and retail. However, explaining the decisions made by these AI…

Artificial Intelligence · Computer Science 2024-10-29 Arne Grobrugge , Nidhi Mishra , Johannes Jakubik , Gerhard Satzger

This study explores the integration of multiple Explainable AI (XAI) techniques to enhance the interpretability of deep learning models for brain tumour detection. A custom Convolutional Neural Network (CNN) was developed and trained on the…

Artificial Intelligence · Computer Science 2026-02-06 Patrick McGonagle , William Farrelly , Kevin Curran

The field of explainable artificial intelligence (XAI) aims to explain how black-box machine learning models work. Much of the work centers around the holy grail of providing post-hoc feature attributions to any model architecture. While…

Machine Learning · Computer Science 2023-11-15 Brian Barr , Noah Fatsi , Leif Hancox-Li , Peter Richter , Daniel Proano , Caleb Mok

Attribution methods correspond to a class of explainability methods (XAI) that aim to assess how individual inputs contribute to a model's decision-making process. We have identified a significant limitation in one type of attribution…

Artificial Intelligence · Computer Science 2024-06-11 Sabine Muzellec , Thomas Fel , Victor Boutin , Léo andéol , Rufin VanRullen , Thomas Serre